7ZEG
Human cytosolic 5' nucleotidase IIIB in complex with 3,4-diF-Bn7GMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0000288 | biological_process | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008253 | molecular_function | 5'-nucleotidase activity |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0000288 | biological_process | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008253 | molecular_function | 5'-nucleotidase activity |
| B | 0009117 | biological_process | nucleotide metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:Q9W197 |
| Chain | Residue | Details |
| A | ASP41 | |
| B | ASP41 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:Q9W197 |
| Chain | Residue | Details |
| A | ASP43 | |
| B | ASP43 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9W197 |
| Chain | Residue | Details |
| A | ASP41 | |
| A | ASP43 | |
| A | GLU88 | |
| A | ASP230 | |
| B | ASP41 | |
| B | ASP43 | |
| B | GLU88 | |
| B | ASP230 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9H0P0 |
| Chain | Residue | Details |
| A | SER156 | |
| A | LYS205 | |
| B | SER156 | |
| B | LYS205 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS256 | |
| B | LYS256 |
