7Z8L

Cytoplasmic dynein light intermediate chain (B1) bound to the motor domain (A2).

Functional Information from GO Data

Chain	GOid	namespace	contents
f	0000166	molecular_function	nucleotide binding
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005524	molecular_function	ATP binding
f	0005576	cellular_component	extracellular region
f	0005737	cellular_component	cytoplasm
f	0005813	cellular_component	centrosome
f	0005829	cellular_component	cytosol
f	0005856	cellular_component	cytoskeleton
f	0005868	cellular_component	cytoplasmic dynein complex
f	0005874	cellular_component	microtubule
f	0005881	cellular_component	cytoplasmic microtubule
f	0005938	cellular_component	cell cortex
f	0007018	biological_process	microtubule-based movement
f	0007052	biological_process	mitotic spindle organization
f	0007097	biological_process	nuclear migration
f	0008090	biological_process	retrograde axonal transport
f	0008569	molecular_function	minus-end-directed microtubule motor activity
f	0016020	cellular_component	membrane
f	0030175	cellular_component	filopodium
f	0030286	cellular_component	dynein complex
f	0031122	biological_process	cytoplasmic microtubule organization
f	0032388	biological_process	positive regulation of intracellular transport
f	0033962	biological_process	P-body assembly
f	0034063	biological_process	stress granule assembly
f	0035578	cellular_component	azurophil granule lumen
f	0042802	molecular_function	identical protein binding
f	0045505	molecular_function	dynein intermediate chain binding
f	0051293	biological_process	establishment of spindle localization
f	0051301	biological_process	cell division
f	0051959	molecular_function	dynein light intermediate chain binding
f	0060236	biological_process	regulation of mitotic spindle organization
f	0070062	cellular_component	extracellular exosome
f	0090235	biological_process	regulation of metaphase plate congression
f	0120162	biological_process	positive regulation of cold-induced thermogenesis
f	1904115	cellular_component	axon cytoplasm
f	1905832	biological_process	positive regulation of spindle assembly
q	0000166	molecular_function	nucleotide binding
q	0000226	biological_process	microtubule cytoskeleton organization
q	0000776	cellular_component	kinetochore
q	0005524	molecular_function	ATP binding
q	0005770	cellular_component	late endosome
q	0005813	cellular_component	centrosome
q	0005829	cellular_component	cytosol
q	0005856	cellular_component	cytoskeleton
q	0005868	cellular_component	cytoplasmic dynein complex
q	0005874	cellular_component	microtubule
q	0007018	biological_process	microtubule-based movement
q	0016020	cellular_component	membrane
q	0030286	cellular_component	dynein complex
q	0032388	biological_process	positive regulation of intracellular transport
q	0042802	molecular_function	identical protein binding
q	0045504	molecular_function	dynein heavy chain binding
q	0051642	biological_process	centrosome localization
q	1990090	biological_process	cellular response to nerve growth factor stimulus

Functional Information from PROSITE/UniProt

site_id	PS00639
Number of Residues	11
Details	THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. INHGLMMVGPS

Chain	Residue	Details
f	ILE2216-SER2226

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	272
Details	Region: {"description":"AAA 2","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	21
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	249
Details	Region: {"description":"AAA 3","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	269
Details	Region: {"description":"AAA 4","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	229
Details	Region: {"description":"AAA 5","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	216
Details	Region: {"description":"AAA 6","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	79
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	35
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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