7Z68

Pseudomonas aeruginosa Elastase in complex with a Thiol based inhibitor (R-and S-configured)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0006508	biological_process	proteolysis

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEVSHGF

Chain	Residue	Details
A	VAL137-PHE146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000305|PubMed:1899664

Chain	Residue	Details
A	GLU141

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:1899664

Chain	Residue	Details
A	HIS223

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:1899664, ECO:0000269|Ref.16, ECO:0000269|Ref.17

Chain	Residue	Details
A	ASP136
A	HIS140
A	HIS144
A	GLU164
A	GLU172
A	GLU175
A	ASP183
A	LEU185

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