Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

7Z22

Connexin43 gap junction channel structure in nanodisc

Functional Information from GO Data
ChainGOidnamespacecontents
A0000132biological_processestablishment of mitotic spindle orientation
A0000139cellular_componentGolgi membrane
A0003161biological_processcardiac conduction system development
A0005243molecular_functiongap junction channel activity
A0005515molecular_functionprotein binding
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005794cellular_componentGolgi apparatus
A0005886cellular_componentplasma membrane
A0005921cellular_componentgap junction
A0005922cellular_componentconnexin complex
A0005925cellular_componentfocal adhesion
A0007154biological_processcell communication
A0007165biological_processsignal transduction
A0007267biological_processcell-cell signaling
A0007283biological_processspermatogenesis
A0007507biological_processheart development
A0008013molecular_functionbeta-catenin binding
A0008104biological_processprotein localization
A0010628biological_processpositive regulation of gene expression
A0010644biological_processcell communication by electrical coupling
A0014047biological_processglutamate secretion
A0014704cellular_componentintercalated disc
A0015075molecular_functionmonoatomic ion transmembrane transporter activity
A0015562molecular_functionefflux transmembrane transporter activity
A0015631molecular_functiontubulin binding
A0016020cellular_componentmembrane
A0016264biological_processgap junction assembly
A0016324cellular_componentapical plasma membrane
A0022857molecular_functiontransmembrane transporter activity
A0030054cellular_componentcell junction
A0030308biological_processnegative regulation of cell growth
A0030660cellular_componentGolgi-associated vesicle membrane
A0032277biological_processnegative regulation of gonadotropin secretion
A0034220biological_processmonoatomic ion transmembrane transport
A0034634molecular_functionglutathione transmembrane transporter activity
A0034775biological_processglutathione transmembrane transport
A0035633biological_processmaintenance of blood-brain barrier
A0042908biological_processxenobiotic transport
A0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
A0044291cellular_componentcell-cell contact zone
A0045121cellular_componentmembrane raft
A0045216biological_processcell-cell junction organization
A0046849biological_processbone remodeling
A0055077molecular_functiongap junction hemi-channel activity
A0060348biological_processbone development
A0070160cellular_componenttight junction
A0070161cellular_componentanchoring junction
A0086014biological_processatrial cardiac muscle cell action potential
A0086064biological_processcell communication by electrical coupling involved in cardiac conduction
A0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
A0120162biological_processpositive regulation of cold-induced thermogenesis
A0140115biological_processexport across plasma membrane
A1901164biological_processnegative regulation of trophoblast cell migration
A1903522biological_processregulation of blood circulation
A1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
A1904646biological_processcellular response to amyloid-beta
A1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
A1905332biological_processpositive regulation of morphogenesis of an epithelium
A1905772biological_processpositive regulation of mesodermal cell differentiation
A2000648biological_processpositive regulation of stem cell proliferation
B0000132biological_processestablishment of mitotic spindle orientation
B0000139cellular_componentGolgi membrane
B0003161biological_processcardiac conduction system development
B0005243molecular_functiongap junction channel activity
B0005515molecular_functionprotein binding
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0005794cellular_componentGolgi apparatus
B0005886cellular_componentplasma membrane
B0005921cellular_componentgap junction
B0005922cellular_componentconnexin complex
B0005925cellular_componentfocal adhesion
B0007154biological_processcell communication
B0007165biological_processsignal transduction
B0007267biological_processcell-cell signaling
B0007283biological_processspermatogenesis
B0007507biological_processheart development
B0008013molecular_functionbeta-catenin binding
B0008104biological_processprotein localization
B0010628biological_processpositive regulation of gene expression
B0010644biological_processcell communication by electrical coupling
B0014047biological_processglutamate secretion
B0014704cellular_componentintercalated disc
B0015075molecular_functionmonoatomic ion transmembrane transporter activity
B0015562molecular_functionefflux transmembrane transporter activity
B0015631molecular_functiontubulin binding
B0016020cellular_componentmembrane
B0016264biological_processgap junction assembly
B0016324cellular_componentapical plasma membrane
B0022857molecular_functiontransmembrane transporter activity
B0030054cellular_componentcell junction
B0030308biological_processnegative regulation of cell growth
B0030660cellular_componentGolgi-associated vesicle membrane
B0032277biological_processnegative regulation of gonadotropin secretion
B0034220biological_processmonoatomic ion transmembrane transport
B0034634molecular_functionglutathione transmembrane transporter activity
B0034775biological_processglutathione transmembrane transport
B0035633biological_processmaintenance of blood-brain barrier
B0042908biological_processxenobiotic transport
B0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
B0044291cellular_componentcell-cell contact zone
B0045121cellular_componentmembrane raft
B0045216biological_processcell-cell junction organization
B0046849biological_processbone remodeling
B0055077molecular_functiongap junction hemi-channel activity
B0060348biological_processbone development
B0070160cellular_componenttight junction
B0070161cellular_componentanchoring junction
B0086014biological_processatrial cardiac muscle cell action potential
B0086064biological_processcell communication by electrical coupling involved in cardiac conduction
B0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
B0120162biological_processpositive regulation of cold-induced thermogenesis
B0140115biological_processexport across plasma membrane
B1901164biological_processnegative regulation of trophoblast cell migration
B1903522biological_processregulation of blood circulation
B1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
B1904646biological_processcellular response to amyloid-beta
B1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
B1905332biological_processpositive regulation of morphogenesis of an epithelium
B1905772biological_processpositive regulation of mesodermal cell differentiation
B2000648biological_processpositive regulation of stem cell proliferation
C0000132biological_processestablishment of mitotic spindle orientation
C0000139cellular_componentGolgi membrane
C0003161biological_processcardiac conduction system development
C0005243molecular_functiongap junction channel activity
C0005515molecular_functionprotein binding
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005783cellular_componentendoplasmic reticulum
C0005789cellular_componentendoplasmic reticulum membrane
C0005794cellular_componentGolgi apparatus
C0005886cellular_componentplasma membrane
C0005921cellular_componentgap junction
C0005922cellular_componentconnexin complex
C0005925cellular_componentfocal adhesion
C0007154biological_processcell communication
C0007165biological_processsignal transduction
C0007267biological_processcell-cell signaling
C0007283biological_processspermatogenesis
C0007507biological_processheart development
C0008013molecular_functionbeta-catenin binding
C0008104biological_processprotein localization
C0010628biological_processpositive regulation of gene expression
C0010644biological_processcell communication by electrical coupling
C0014047biological_processglutamate secretion
C0014704cellular_componentintercalated disc
C0015075molecular_functionmonoatomic ion transmembrane transporter activity
C0015562molecular_functionefflux transmembrane transporter activity
C0015631molecular_functiontubulin binding
C0016020cellular_componentmembrane
C0016264biological_processgap junction assembly
C0016324cellular_componentapical plasma membrane
C0022857molecular_functiontransmembrane transporter activity
C0030054cellular_componentcell junction
C0030308biological_processnegative regulation of cell growth
C0030660cellular_componentGolgi-associated vesicle membrane
C0032277biological_processnegative regulation of gonadotropin secretion
C0034220biological_processmonoatomic ion transmembrane transport
C0034634molecular_functionglutathione transmembrane transporter activity
C0034775biological_processglutathione transmembrane transport
C0035633biological_processmaintenance of blood-brain barrier
C0042908biological_processxenobiotic transport
C0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
C0044291cellular_componentcell-cell contact zone
C0045121cellular_componentmembrane raft
C0045216biological_processcell-cell junction organization
C0046849biological_processbone remodeling
C0055077molecular_functiongap junction hemi-channel activity
C0060348biological_processbone development
C0070160cellular_componenttight junction
C0070161cellular_componentanchoring junction
C0086014biological_processatrial cardiac muscle cell action potential
C0086064biological_processcell communication by electrical coupling involved in cardiac conduction
C0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
C0120162biological_processpositive regulation of cold-induced thermogenesis
C0140115biological_processexport across plasma membrane
C1901164biological_processnegative regulation of trophoblast cell migration
C1903522biological_processregulation of blood circulation
C1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
C1904646biological_processcellular response to amyloid-beta
C1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
C1905332biological_processpositive regulation of morphogenesis of an epithelium
C1905772biological_processpositive regulation of mesodermal cell differentiation
C2000648biological_processpositive regulation of stem cell proliferation
D0000132biological_processestablishment of mitotic spindle orientation
D0000139cellular_componentGolgi membrane
D0003161biological_processcardiac conduction system development
D0005243molecular_functiongap junction channel activity
D0005515molecular_functionprotein binding
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005783cellular_componentendoplasmic reticulum
D0005789cellular_componentendoplasmic reticulum membrane
D0005794cellular_componentGolgi apparatus
D0005886cellular_componentplasma membrane
D0005921cellular_componentgap junction
D0005922cellular_componentconnexin complex
D0005925cellular_componentfocal adhesion
D0007154biological_processcell communication
D0007165biological_processsignal transduction
D0007267biological_processcell-cell signaling
D0007283biological_processspermatogenesis
D0007507biological_processheart development
D0008013molecular_functionbeta-catenin binding
D0008104biological_processprotein localization
D0010628biological_processpositive regulation of gene expression
D0010644biological_processcell communication by electrical coupling
D0014047biological_processglutamate secretion
D0014704cellular_componentintercalated disc
D0015075molecular_functionmonoatomic ion transmembrane transporter activity
D0015562molecular_functionefflux transmembrane transporter activity
D0015631molecular_functiontubulin binding
D0016020cellular_componentmembrane
D0016264biological_processgap junction assembly
D0016324cellular_componentapical plasma membrane
D0022857molecular_functiontransmembrane transporter activity
D0030054cellular_componentcell junction
D0030308biological_processnegative regulation of cell growth
D0030660cellular_componentGolgi-associated vesicle membrane
D0032277biological_processnegative regulation of gonadotropin secretion
D0034220biological_processmonoatomic ion transmembrane transport
D0034634molecular_functionglutathione transmembrane transporter activity
D0034775biological_processglutathione transmembrane transport
D0035633biological_processmaintenance of blood-brain barrier
D0042908biological_processxenobiotic transport
D0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
D0044291cellular_componentcell-cell contact zone
D0045121cellular_componentmembrane raft
D0045216biological_processcell-cell junction organization
D0046849biological_processbone remodeling
D0055077molecular_functiongap junction hemi-channel activity
D0060348biological_processbone development
D0070160cellular_componenttight junction
D0070161cellular_componentanchoring junction
D0086014biological_processatrial cardiac muscle cell action potential
D0086064biological_processcell communication by electrical coupling involved in cardiac conduction
D0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
D0120162biological_processpositive regulation of cold-induced thermogenesis
D0140115biological_processexport across plasma membrane
D1901164biological_processnegative regulation of trophoblast cell migration
D1903522biological_processregulation of blood circulation
D1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
D1904646biological_processcellular response to amyloid-beta
D1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
D1905332biological_processpositive regulation of morphogenesis of an epithelium
D1905772biological_processpositive regulation of mesodermal cell differentiation
D2000648biological_processpositive regulation of stem cell proliferation
E0000132biological_processestablishment of mitotic spindle orientation
E0000139cellular_componentGolgi membrane
E0003161biological_processcardiac conduction system development
E0005243molecular_functiongap junction channel activity
E0005515molecular_functionprotein binding
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005739cellular_componentmitochondrion
E0005783cellular_componentendoplasmic reticulum
E0005789cellular_componentendoplasmic reticulum membrane
E0005794cellular_componentGolgi apparatus
E0005886cellular_componentplasma membrane
E0005921cellular_componentgap junction
E0005922cellular_componentconnexin complex
E0005925cellular_componentfocal adhesion
E0007154biological_processcell communication
E0007165biological_processsignal transduction
E0007267biological_processcell-cell signaling
E0007283biological_processspermatogenesis
E0007507biological_processheart development
E0008013molecular_functionbeta-catenin binding
E0008104biological_processprotein localization
E0010628biological_processpositive regulation of gene expression
E0010644biological_processcell communication by electrical coupling
E0014047biological_processglutamate secretion
E0014704cellular_componentintercalated disc
E0015075molecular_functionmonoatomic ion transmembrane transporter activity
E0015562molecular_functionefflux transmembrane transporter activity
E0015631molecular_functiontubulin binding
E0016020cellular_componentmembrane
E0016264biological_processgap junction assembly
E0016324cellular_componentapical plasma membrane
E0022857molecular_functiontransmembrane transporter activity
E0030054cellular_componentcell junction
E0030308biological_processnegative regulation of cell growth
E0030660cellular_componentGolgi-associated vesicle membrane
E0032277biological_processnegative regulation of gonadotropin secretion
E0034220biological_processmonoatomic ion transmembrane transport
E0034634molecular_functionglutathione transmembrane transporter activity
E0034775biological_processglutathione transmembrane transport
E0035633biological_processmaintenance of blood-brain barrier
E0042908biological_processxenobiotic transport
E0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
E0044291cellular_componentcell-cell contact zone
E0045121cellular_componentmembrane raft
E0045216biological_processcell-cell junction organization
E0046849biological_processbone remodeling
E0055077molecular_functiongap junction hemi-channel activity
E0060348biological_processbone development
E0070160cellular_componenttight junction
E0070161cellular_componentanchoring junction
E0086014biological_processatrial cardiac muscle cell action potential
E0086064biological_processcell communication by electrical coupling involved in cardiac conduction
E0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
E0120162biological_processpositive regulation of cold-induced thermogenesis
E0140115biological_processexport across plasma membrane
E1901164biological_processnegative regulation of trophoblast cell migration
E1903522biological_processregulation of blood circulation
E1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
E1904646biological_processcellular response to amyloid-beta
E1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
E1905332biological_processpositive regulation of morphogenesis of an epithelium
E1905772biological_processpositive regulation of mesodermal cell differentiation
E2000648biological_processpositive regulation of stem cell proliferation
F0000132biological_processestablishment of mitotic spindle orientation
F0000139cellular_componentGolgi membrane
F0003161biological_processcardiac conduction system development
F0005243molecular_functiongap junction channel activity
F0005515molecular_functionprotein binding
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005783cellular_componentendoplasmic reticulum
F0005789cellular_componentendoplasmic reticulum membrane
F0005794cellular_componentGolgi apparatus
F0005886cellular_componentplasma membrane
F0005921cellular_componentgap junction
F0005922cellular_componentconnexin complex
F0005925cellular_componentfocal adhesion
F0007154biological_processcell communication
F0007165biological_processsignal transduction
F0007267biological_processcell-cell signaling
F0007283biological_processspermatogenesis
F0007507biological_processheart development
F0008013molecular_functionbeta-catenin binding
F0008104biological_processprotein localization
F0010628biological_processpositive regulation of gene expression
F0010644biological_processcell communication by electrical coupling
F0014047biological_processglutamate secretion
F0014704cellular_componentintercalated disc
F0015075molecular_functionmonoatomic ion transmembrane transporter activity
F0015562molecular_functionefflux transmembrane transporter activity
F0015631molecular_functiontubulin binding
F0016020cellular_componentmembrane
F0016264biological_processgap junction assembly
F0016324cellular_componentapical plasma membrane
F0022857molecular_functiontransmembrane transporter activity
F0030054cellular_componentcell junction
F0030308biological_processnegative regulation of cell growth
F0030660cellular_componentGolgi-associated vesicle membrane
F0032277biological_processnegative regulation of gonadotropin secretion
F0034220biological_processmonoatomic ion transmembrane transport
F0034634molecular_functionglutathione transmembrane transporter activity
F0034775biological_processglutathione transmembrane transport
F0035633biological_processmaintenance of blood-brain barrier
F0042908biological_processxenobiotic transport
F0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
F0044291cellular_componentcell-cell contact zone
F0045121cellular_componentmembrane raft
F0045216biological_processcell-cell junction organization
F0046849biological_processbone remodeling
F0055077molecular_functiongap junction hemi-channel activity
F0060348biological_processbone development
F0070160cellular_componenttight junction
F0070161cellular_componentanchoring junction
F0086014biological_processatrial cardiac muscle cell action potential
F0086064biological_processcell communication by electrical coupling involved in cardiac conduction
F0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
F0120162biological_processpositive regulation of cold-induced thermogenesis
F0140115biological_processexport across plasma membrane
F1901164biological_processnegative regulation of trophoblast cell migration
F1903522biological_processregulation of blood circulation
F1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
F1904646biological_processcellular response to amyloid-beta
F1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
F1905332biological_processpositive regulation of morphogenesis of an epithelium
F1905772biological_processpositive regulation of mesodermal cell differentiation
F2000648biological_processpositive regulation of stem cell proliferation
G0000132biological_processestablishment of mitotic spindle orientation
G0000139cellular_componentGolgi membrane
G0003161biological_processcardiac conduction system development
G0005243molecular_functiongap junction channel activity
G0005515molecular_functionprotein binding
G0005654cellular_componentnucleoplasm
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005783cellular_componentendoplasmic reticulum
G0005789cellular_componentendoplasmic reticulum membrane
G0005794cellular_componentGolgi apparatus
G0005886cellular_componentplasma membrane
G0005921cellular_componentgap junction
G0005922cellular_componentconnexin complex
G0005925cellular_componentfocal adhesion
G0007154biological_processcell communication
G0007165biological_processsignal transduction
G0007267biological_processcell-cell signaling
G0007283biological_processspermatogenesis
G0007507biological_processheart development
G0008013molecular_functionbeta-catenin binding
G0008104biological_processprotein localization
G0010628biological_processpositive regulation of gene expression
G0010644biological_processcell communication by electrical coupling
G0014047biological_processglutamate secretion
G0014704cellular_componentintercalated disc
G0015075molecular_functionmonoatomic ion transmembrane transporter activity
G0015562molecular_functionefflux transmembrane transporter activity
G0015631molecular_functiontubulin binding
G0016020cellular_componentmembrane
G0016264biological_processgap junction assembly
G0016324cellular_componentapical plasma membrane
G0022857molecular_functiontransmembrane transporter activity
G0030054cellular_componentcell junction
G0030308biological_processnegative regulation of cell growth
G0030660cellular_componentGolgi-associated vesicle membrane
G0032277biological_processnegative regulation of gonadotropin secretion
G0034220biological_processmonoatomic ion transmembrane transport
G0034634molecular_functionglutathione transmembrane transporter activity
G0034775biological_processglutathione transmembrane transport
G0035633biological_processmaintenance of blood-brain barrier
G0042908biological_processxenobiotic transport
G0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
G0044291cellular_componentcell-cell contact zone
G0045121cellular_componentmembrane raft
G0045216biological_processcell-cell junction organization
G0046849biological_processbone remodeling
G0055077molecular_functiongap junction hemi-channel activity
G0060348biological_processbone development
G0070160cellular_componenttight junction
G0070161cellular_componentanchoring junction
G0086014biological_processatrial cardiac muscle cell action potential
G0086064biological_processcell communication by electrical coupling involved in cardiac conduction
G0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
G0120162biological_processpositive regulation of cold-induced thermogenesis
G0140115biological_processexport across plasma membrane
G1901164biological_processnegative regulation of trophoblast cell migration
G1903522biological_processregulation of blood circulation
G1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
G1904646biological_processcellular response to amyloid-beta
G1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
G1905332biological_processpositive regulation of morphogenesis of an epithelium
G1905772biological_processpositive regulation of mesodermal cell differentiation
G2000648biological_processpositive regulation of stem cell proliferation
H0000132biological_processestablishment of mitotic spindle orientation
H0000139cellular_componentGolgi membrane
H0003161biological_processcardiac conduction system development
H0005243molecular_functiongap junction channel activity
H0005515molecular_functionprotein binding
H0005654cellular_componentnucleoplasm
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005783cellular_componentendoplasmic reticulum
H0005789cellular_componentendoplasmic reticulum membrane
H0005794cellular_componentGolgi apparatus
H0005886cellular_componentplasma membrane
H0005921cellular_componentgap junction
H0005922cellular_componentconnexin complex
H0005925cellular_componentfocal adhesion
H0007154biological_processcell communication
H0007165biological_processsignal transduction
H0007267biological_processcell-cell signaling
H0007283biological_processspermatogenesis
H0007507biological_processheart development
H0008013molecular_functionbeta-catenin binding
H0008104biological_processprotein localization
H0010628biological_processpositive regulation of gene expression
H0010644biological_processcell communication by electrical coupling
H0014047biological_processglutamate secretion
H0014704cellular_componentintercalated disc
H0015075molecular_functionmonoatomic ion transmembrane transporter activity
H0015562molecular_functionefflux transmembrane transporter activity
H0015631molecular_functiontubulin binding
H0016020cellular_componentmembrane
H0016264biological_processgap junction assembly
H0016324cellular_componentapical plasma membrane
H0022857molecular_functiontransmembrane transporter activity
H0030054cellular_componentcell junction
H0030308biological_processnegative regulation of cell growth
H0030660cellular_componentGolgi-associated vesicle membrane
H0032277biological_processnegative regulation of gonadotropin secretion
H0034220biological_processmonoatomic ion transmembrane transport
H0034634molecular_functionglutathione transmembrane transporter activity
H0034775biological_processglutathione transmembrane transport
H0035633biological_processmaintenance of blood-brain barrier
H0042908biological_processxenobiotic transport
H0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
H0044291cellular_componentcell-cell contact zone
H0045121cellular_componentmembrane raft
H0045216biological_processcell-cell junction organization
H0046849biological_processbone remodeling
H0055077molecular_functiongap junction hemi-channel activity
H0060348biological_processbone development
H0070160cellular_componenttight junction
H0070161cellular_componentanchoring junction
H0086014biological_processatrial cardiac muscle cell action potential
H0086064biological_processcell communication by electrical coupling involved in cardiac conduction
H0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
H0120162biological_processpositive regulation of cold-induced thermogenesis
H0140115biological_processexport across plasma membrane
H1901164biological_processnegative regulation of trophoblast cell migration
H1903522biological_processregulation of blood circulation
H1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
H1904646biological_processcellular response to amyloid-beta
H1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
H1905332biological_processpositive regulation of morphogenesis of an epithelium
H1905772biological_processpositive regulation of mesodermal cell differentiation
H2000648biological_processpositive regulation of stem cell proliferation
I0000132biological_processestablishment of mitotic spindle orientation
I0000139cellular_componentGolgi membrane
I0003161biological_processcardiac conduction system development
I0005243molecular_functiongap junction channel activity
I0005515molecular_functionprotein binding
I0005654cellular_componentnucleoplasm
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005783cellular_componentendoplasmic reticulum
I0005789cellular_componentendoplasmic reticulum membrane
I0005794cellular_componentGolgi apparatus
I0005886cellular_componentplasma membrane
I0005921cellular_componentgap junction
I0005922cellular_componentconnexin complex
I0005925cellular_componentfocal adhesion
I0007154biological_processcell communication
I0007165biological_processsignal transduction
I0007267biological_processcell-cell signaling
I0007283biological_processspermatogenesis
I0007507biological_processheart development
I0008013molecular_functionbeta-catenin binding
I0008104biological_processprotein localization
I0010628biological_processpositive regulation of gene expression
I0010644biological_processcell communication by electrical coupling
I0014047biological_processglutamate secretion
I0014704cellular_componentintercalated disc
I0015075molecular_functionmonoatomic ion transmembrane transporter activity
I0015562molecular_functionefflux transmembrane transporter activity
I0015631molecular_functiontubulin binding
I0016020cellular_componentmembrane
I0016264biological_processgap junction assembly
I0016324cellular_componentapical plasma membrane
I0022857molecular_functiontransmembrane transporter activity
I0030054cellular_componentcell junction
I0030308biological_processnegative regulation of cell growth
I0030660cellular_componentGolgi-associated vesicle membrane
I0032277biological_processnegative regulation of gonadotropin secretion
I0034220biological_processmonoatomic ion transmembrane transport
I0034634molecular_functionglutathione transmembrane transporter activity
I0034775biological_processglutathione transmembrane transport
I0035633biological_processmaintenance of blood-brain barrier
I0042908biological_processxenobiotic transport
I0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
I0044291cellular_componentcell-cell contact zone
I0045121cellular_componentmembrane raft
I0045216biological_processcell-cell junction organization
I0046849biological_processbone remodeling
I0055077molecular_functiongap junction hemi-channel activity
I0060348biological_processbone development
I0070160cellular_componenttight junction
I0070161cellular_componentanchoring junction
I0086014biological_processatrial cardiac muscle cell action potential
I0086064biological_processcell communication by electrical coupling involved in cardiac conduction
I0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
I0120162biological_processpositive regulation of cold-induced thermogenesis
I0140115biological_processexport across plasma membrane
I1901164biological_processnegative regulation of trophoblast cell migration
I1903522biological_processregulation of blood circulation
I1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
I1904646biological_processcellular response to amyloid-beta
I1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
I1905332biological_processpositive regulation of morphogenesis of an epithelium
I1905772biological_processpositive regulation of mesodermal cell differentiation
I2000648biological_processpositive regulation of stem cell proliferation
J0000132biological_processestablishment of mitotic spindle orientation
J0000139cellular_componentGolgi membrane
J0003161biological_processcardiac conduction system development
J0005243molecular_functiongap junction channel activity
J0005515molecular_functionprotein binding
J0005654cellular_componentnucleoplasm
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005783cellular_componentendoplasmic reticulum
J0005789cellular_componentendoplasmic reticulum membrane
J0005794cellular_componentGolgi apparatus
J0005886cellular_componentplasma membrane
J0005921cellular_componentgap junction
J0005922cellular_componentconnexin complex
J0005925cellular_componentfocal adhesion
J0007154biological_processcell communication
J0007165biological_processsignal transduction
J0007267biological_processcell-cell signaling
J0007283biological_processspermatogenesis
J0007507biological_processheart development
J0008013molecular_functionbeta-catenin binding
J0008104biological_processprotein localization
J0010628biological_processpositive regulation of gene expression
J0010644biological_processcell communication by electrical coupling
J0014047biological_processglutamate secretion
J0014704cellular_componentintercalated disc
J0015075molecular_functionmonoatomic ion transmembrane transporter activity
J0015562molecular_functionefflux transmembrane transporter activity
J0015631molecular_functiontubulin binding
J0016020cellular_componentmembrane
J0016264biological_processgap junction assembly
J0016324cellular_componentapical plasma membrane
J0022857molecular_functiontransmembrane transporter activity
J0030054cellular_componentcell junction
J0030308biological_processnegative regulation of cell growth
J0030660cellular_componentGolgi-associated vesicle membrane
J0032277biological_processnegative regulation of gonadotropin secretion
J0034220biological_processmonoatomic ion transmembrane transport
J0034634molecular_functionglutathione transmembrane transporter activity
J0034775biological_processglutathione transmembrane transport
J0035633biological_processmaintenance of blood-brain barrier
J0042908biological_processxenobiotic transport
J0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
J0044291cellular_componentcell-cell contact zone
J0045121cellular_componentmembrane raft
J0045216biological_processcell-cell junction organization
J0046849biological_processbone remodeling
J0055077molecular_functiongap junction hemi-channel activity
J0060348biological_processbone development
J0070160cellular_componenttight junction
J0070161cellular_componentanchoring junction
J0086014biological_processatrial cardiac muscle cell action potential
J0086064biological_processcell communication by electrical coupling involved in cardiac conduction
J0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
J0120162biological_processpositive regulation of cold-induced thermogenesis
J0140115biological_processexport across plasma membrane
J1901164biological_processnegative regulation of trophoblast cell migration
J1903522biological_processregulation of blood circulation
J1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
J1904646biological_processcellular response to amyloid-beta
J1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
J1905332biological_processpositive regulation of morphogenesis of an epithelium
J1905772biological_processpositive regulation of mesodermal cell differentiation
J2000648biological_processpositive regulation of stem cell proliferation
K0000132biological_processestablishment of mitotic spindle orientation
K0000139cellular_componentGolgi membrane
K0003161biological_processcardiac conduction system development
K0005243molecular_functiongap junction channel activity
K0005515molecular_functionprotein binding
K0005654cellular_componentnucleoplasm
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005783cellular_componentendoplasmic reticulum
K0005789cellular_componentendoplasmic reticulum membrane
K0005794cellular_componentGolgi apparatus
K0005886cellular_componentplasma membrane
K0005921cellular_componentgap junction
K0005922cellular_componentconnexin complex
K0005925cellular_componentfocal adhesion
K0007154biological_processcell communication
K0007165biological_processsignal transduction
K0007267biological_processcell-cell signaling
K0007283biological_processspermatogenesis
K0007507biological_processheart development
K0008013molecular_functionbeta-catenin binding
K0008104biological_processprotein localization
K0010628biological_processpositive regulation of gene expression
K0010644biological_processcell communication by electrical coupling
K0014047biological_processglutamate secretion
K0014704cellular_componentintercalated disc
K0015075molecular_functionmonoatomic ion transmembrane transporter activity
K0015562molecular_functionefflux transmembrane transporter activity
K0015631molecular_functiontubulin binding
K0016020cellular_componentmembrane
K0016264biological_processgap junction assembly
K0016324cellular_componentapical plasma membrane
K0022857molecular_functiontransmembrane transporter activity
K0030054cellular_componentcell junction
K0030308biological_processnegative regulation of cell growth
K0030660cellular_componentGolgi-associated vesicle membrane
K0032277biological_processnegative regulation of gonadotropin secretion
K0034220biological_processmonoatomic ion transmembrane transport
K0034634molecular_functionglutathione transmembrane transporter activity
K0034775biological_processglutathione transmembrane transport
K0035633biological_processmaintenance of blood-brain barrier
K0042908biological_processxenobiotic transport
K0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
K0044291cellular_componentcell-cell contact zone
K0045121cellular_componentmembrane raft
K0045216biological_processcell-cell junction organization
K0046849biological_processbone remodeling
K0055077molecular_functiongap junction hemi-channel activity
K0060348biological_processbone development
K0070160cellular_componenttight junction
K0070161cellular_componentanchoring junction
K0086014biological_processatrial cardiac muscle cell action potential
K0086064biological_processcell communication by electrical coupling involved in cardiac conduction
K0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
K0120162biological_processpositive regulation of cold-induced thermogenesis
K0140115biological_processexport across plasma membrane
K1901164biological_processnegative regulation of trophoblast cell migration
K1903522biological_processregulation of blood circulation
K1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
K1904646biological_processcellular response to amyloid-beta
K1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
K1905332biological_processpositive regulation of morphogenesis of an epithelium
K1905772biological_processpositive regulation of mesodermal cell differentiation
K2000648biological_processpositive regulation of stem cell proliferation
L0000132biological_processestablishment of mitotic spindle orientation
L0000139cellular_componentGolgi membrane
L0003161biological_processcardiac conduction system development
L0005243molecular_functiongap junction channel activity
L0005515molecular_functionprotein binding
L0005654cellular_componentnucleoplasm
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005783cellular_componentendoplasmic reticulum
L0005789cellular_componentendoplasmic reticulum membrane
L0005794cellular_componentGolgi apparatus
L0005886cellular_componentplasma membrane
L0005921cellular_componentgap junction
L0005922cellular_componentconnexin complex
L0005925cellular_componentfocal adhesion
L0007154biological_processcell communication
L0007165biological_processsignal transduction
L0007267biological_processcell-cell signaling
L0007283biological_processspermatogenesis
L0007507biological_processheart development
L0008013molecular_functionbeta-catenin binding
L0008104biological_processprotein localization
L0010628biological_processpositive regulation of gene expression
L0010644biological_processcell communication by electrical coupling
L0014047biological_processglutamate secretion
L0014704cellular_componentintercalated disc
L0015075molecular_functionmonoatomic ion transmembrane transporter activity
L0015562molecular_functionefflux transmembrane transporter activity
L0015631molecular_functiontubulin binding
L0016020cellular_componentmembrane
L0016264biological_processgap junction assembly
L0016324cellular_componentapical plasma membrane
L0022857molecular_functiontransmembrane transporter activity
L0030054cellular_componentcell junction
L0030308biological_processnegative regulation of cell growth
L0030660cellular_componentGolgi-associated vesicle membrane
L0032277biological_processnegative regulation of gonadotropin secretion
L0034220biological_processmonoatomic ion transmembrane transport
L0034634molecular_functionglutathione transmembrane transporter activity
L0034775biological_processglutathione transmembrane transport
L0035633biological_processmaintenance of blood-brain barrier
L0042908biological_processxenobiotic transport
L0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
L0044291cellular_componentcell-cell contact zone
L0045121cellular_componentmembrane raft
L0045216biological_processcell-cell junction organization
L0046849biological_processbone remodeling
L0055077molecular_functiongap junction hemi-channel activity
L0060348biological_processbone development
L0070160cellular_componenttight junction
L0070161cellular_componentanchoring junction
L0086014biological_processatrial cardiac muscle cell action potential
L0086064biological_processcell communication by electrical coupling involved in cardiac conduction
L0086075molecular_functiongap junction channel activity involved in cardiac conduction electrical coupling
L0120162biological_processpositive regulation of cold-induced thermogenesis
L0140115biological_processexport across plasma membrane
L1901164biological_processnegative regulation of trophoblast cell migration
L1903522biological_processregulation of blood circulation
L1903763molecular_functiongap junction channel activity involved in cell communication by electrical coupling
L1904646biological_processcellular response to amyloid-beta
L1904707biological_processpositive regulation of vascular associated smooth muscle cell proliferation
L1905332biological_processpositive regulation of morphogenesis of an epithelium
L1905772biological_processpositive regulation of mesodermal cell differentiation
L2000648biological_processpositive regulation of stem cell proliferation
Functional Information from PROSITE/UniProt
site_idPS00407
Number of Residues14
DetailsCONNEXINS_1 Connexins signature 1. CNTqQPGCenVCYD
ChainResidueDetails
ACYS54-ASP67

site_idPS00408
Number of Residues17
DetailsCONNEXINS_2 Connexins signature 2. Ckrd.PCphqVDCFLSRP
ChainResidueDetails
ACYS187-PRO203

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues252
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"UniProtKB","id":"P08050","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues960
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues732
DetailsTopological domain: {"description":"Extracellular","evidences":[{"source":"UniProtKB","id":"P08050","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues12
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P08050","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

238582

PDB entries from 2025-07-09

PDB statisticsPDBj update infoContact PDBjnumon