7Z0S

Structure of the Escherichia coli formate hydrogenlyase complex (anaerobic preparation, without formate dehydrogenase H)

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0006007	biological_process	glucose catabolic process
B	0009061	biological_process	anaerobic respiration
B	0009326	cellular_component	formate dehydrogenase complex
B	0015944	biological_process	formate oxidation
B	0019645	biological_process	anaerobic electron transport chain
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0005886	cellular_component	plasma membrane
C	0006007	biological_process	glucose catabolic process
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0009061	biological_process	anaerobic respiration
C	0009326	cellular_component	formate dehydrogenase complex
C	0015944	biological_process	formate oxidation
C	0016491	molecular_function	oxidoreductase activity
C	0019645	biological_process	anaerobic electron transport chain
C	0042773	biological_process	ATP synthesis coupled electron transport
C	1902600	biological_process	proton transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006007	biological_process	glucose catabolic process
D	0009061	biological_process	anaerobic respiration
D	0009326	cellular_component	formate dehydrogenase complex
D	0015944	biological_process	formate oxidation
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0019645	biological_process	anaerobic electron transport chain
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0016151	molecular_function	nickel cation binding
E	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
E	0048038	molecular_function	quinone binding
E	0051287	molecular_function	NAD binding
F	0003954	molecular_function	NADH dehydrogenase activity
F	0006007	biological_process	glucose catabolic process
F	0009060	biological_process	aerobic respiration
F	0009061	biological_process	anaerobic respiration
F	0009326	cellular_component	formate dehydrogenase complex
F	0015944	biological_process	formate oxidation
F	0016020	cellular_component	membrane
F	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
F	0019645	biological_process	anaerobic electron transport chain
F	0046872	molecular_function	metal ion binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	0005515	molecular_function	protein binding
G	0006007	biological_process	glucose catabolic process
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0009061	biological_process	anaerobic respiration
G	0009326	cellular_component	formate dehydrogenase complex
G	0015944	biological_process	formate oxidation
G	0016491	molecular_function	oxidoreductase activity
G	0019645	biological_process	anaerobic electron transport chain
G	0046872	molecular_function	metal ion binding
G	0048038	molecular_function	quinone binding
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CvSCKlCGiACP

Chain	Residue	Details
B	CYS82-PRO93
F	CYS40-PRO51
F	CYS75-PRO86

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. VHRGmEKLaEtR

Chain	Residue	Details
E	VAL216-ARG227

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GVLQeYrDIIKLLgRQ

Chain	Residue	Details
D	GLY38-GLN53

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLAEAEq.ELqeG

Chain	Residue	Details
D	PRO194-GLY207

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GtDKIVPVDVYiPgCPP

Chain	Residue	Details
G	GLY131-PRO147

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	407
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	59
Details	Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	59
Details	Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	29
Details	Domain: {"description":"4Fe-4S ferredoxin-type 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	32
Details	Domain: {"description":"4Fe-4S ferredoxin-type 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	100
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	29
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---