7YRR

Cryo-EM structure of IGF1R with two IGF1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
C	0008083	molecular_function	growth factor activity
D	0005179	molecular_function	hormone activity
D	0005576	cellular_component	extracellular region
D	0008083	molecular_function	growth factor activity

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCFRsCDlrrLemyC

Chain	Residue	Details
C	CYS47-CYS61

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	186
Details	Domain: {"description":"Fibronectin type-III 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"9690478","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	18
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	40
Details	Region: {"description":"A"}

Chain

Residue

Details

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