Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7YLX

yeast TRiC-plp2-actin complex at S4 closed TRiC state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005886	cellular_component	plasma membrane
A	0006457	biological_process	protein folding
A	0016887	molecular_function	ATP hydrolysis activity
A	0051082	molecular_function	unfolded protein binding
A	0140662	molecular_function	ATP-dependent protein folding chaperone
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0006457	biological_process	protein folding
B	0016887	molecular_function	ATP hydrolysis activity
B	0051082	molecular_function	unfolded protein binding
B	0140662	molecular_function	ATP-dependent protein folding chaperone
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005832	cellular_component	chaperonin-containing T-complex
D	0006457	biological_process	protein folding
D	0016887	molecular_function	ATP hydrolysis activity
D	0051082	molecular_function	unfolded protein binding
D	0140662	molecular_function	ATP-dependent protein folding chaperone
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005832	cellular_component	chaperonin-containing T-complex
E	0006457	biological_process	protein folding
E	0016887	molecular_function	ATP hydrolysis activity
E	0051082	molecular_function	unfolded protein binding
E	0140662	molecular_function	ATP-dependent protein folding chaperone
G	0005524	molecular_function	ATP binding
G	0006457	biological_process	protein folding
G	0016887	molecular_function	ATP hydrolysis activity
G	0051082	molecular_function	unfolded protein binding
G	0140662	molecular_function	ATP-dependent protein folding chaperone
H	0000166	molecular_function	nucleotide binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005832	cellular_component	chaperonin-containing T-complex
H	0006457	biological_process	protein folding
H	0016887	molecular_function	ATP hydrolysis activity
H	0051082	molecular_function	unfolded protein binding
H	0140662	molecular_function	ATP-dependent protein folding chaperone
Q	0000166	molecular_function	nucleotide binding
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005832	cellular_component	chaperonin-containing T-complex
Q	0006457	biological_process	protein folding
Q	0016887	molecular_function	ATP hydrolysis activity
Q	0051082	molecular_function	unfolded protein binding
Q	0140662	molecular_function	ATP-dependent protein folding chaperone
Z	0000166	molecular_function	nucleotide binding
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005832	cellular_component	chaperonin-containing T-complex
Z	0006457	biological_process	protein folding
Z	0016887	molecular_function	ATP hydrolysis activity
Z	0051082	molecular_function	unfolded protein binding
Z	0140662	molecular_function	ATP-dependent protein folding chaperone
a	0000166	molecular_function	nucleotide binding
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005737	cellular_component	cytoplasm
a	0005832	cellular_component	chaperonin-containing T-complex
a	0005886	cellular_component	plasma membrane
a	0006457	biological_process	protein folding
a	0016887	molecular_function	ATP hydrolysis activity
a	0051082	molecular_function	unfolded protein binding
a	0140662	molecular_function	ATP-dependent protein folding chaperone
b	0000166	molecular_function	nucleotide binding
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005832	cellular_component	chaperonin-containing T-complex
b	0006457	biological_process	protein folding
b	0016887	molecular_function	ATP hydrolysis activity
b	0051082	molecular_function	unfolded protein binding
b	0140662	molecular_function	ATP-dependent protein folding chaperone
d	0000166	molecular_function	nucleotide binding
d	0005524	molecular_function	ATP binding
d	0005737	cellular_component	cytoplasm
d	0005832	cellular_component	chaperonin-containing T-complex
d	0006457	biological_process	protein folding
d	0016887	molecular_function	ATP hydrolysis activity
d	0051082	molecular_function	unfolded protein binding
d	0140662	molecular_function	ATP-dependent protein folding chaperone
e	0000166	molecular_function	nucleotide binding
e	0005524	molecular_function	ATP binding
e	0005737	cellular_component	cytoplasm
e	0005832	cellular_component	chaperonin-containing T-complex
e	0006457	biological_process	protein folding
e	0016887	molecular_function	ATP hydrolysis activity
e	0051082	molecular_function	unfolded protein binding
e	0140662	molecular_function	ATP-dependent protein folding chaperone
g	0005524	molecular_function	ATP binding
g	0006457	biological_process	protein folding
g	0016887	molecular_function	ATP hydrolysis activity
g	0051082	molecular_function	unfolded protein binding
g	0140662	molecular_function	ATP-dependent protein folding chaperone
h	0000166	molecular_function	nucleotide binding
h	0005524	molecular_function	ATP binding
h	0005737	cellular_component	cytoplasm
h	0005832	cellular_component	chaperonin-containing T-complex
h	0006457	biological_process	protein folding
h	0016887	molecular_function	ATP hydrolysis activity
h	0051082	molecular_function	unfolded protein binding
h	0140662	molecular_function	ATP-dependent protein folding chaperone
p	0003779	molecular_function	actin binding
p	0005515	molecular_function	protein binding
p	0005737	cellular_component	cytoplasm
p	0006457	biological_process	protein folding
p	0009968	biological_process	negative regulation of signal transduction
p	0019236	biological_process	response to pheromone
p	0030036	biological_process	actin cytoskeleton organization
p	0031683	molecular_function	G-protein beta/gamma-subunit complex binding
p	0045944	biological_process	positive regulation of transcription by RNA polymerase II
p	0051726	biological_process	regulation of cell cycle
p	0071444	biological_process	cellular response to pheromone
p	1903333	biological_process	negative regulation of protein folding
q	0000166	molecular_function	nucleotide binding
q	0005524	molecular_function	ATP binding
q	0005737	cellular_component	cytoplasm
q	0005832	cellular_component	chaperonin-containing T-complex
q	0006457	biological_process	protein folding
q	0016887	molecular_function	ATP hydrolysis activity
q	0051082	molecular_function	unfolded protein binding
q	0140662	molecular_function	ATP-dependent protein folding chaperone
z	0000166	molecular_function	nucleotide binding
z	0005524	molecular_function	ATP binding
z	0005737	cellular_component	cytoplasm
z	0005832	cellular_component	chaperonin-containing T-complex
z	0006457	biological_process	protein folding
z	0016887	molecular_function	ATP hydrolysis activity
z	0051082	molecular_function	unfolded protein binding
z	0140662	molecular_function	ATP-dependent protein folding chaperone

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	34
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTIlAgelmkeakpfleegisshLIMK

Chain	Residue	Details
H	VAL94-LYS127

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. LTsMGPcGrnKII

Chain	Residue	Details
Q	LEU43-ILE55
Z	GLU34-LEU46
B	LYS34-LEU46
A	LYS41-LEU53
D	ARG36-ILE48
E	LYS62-LEU74
G	ARG36-LEU48

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. ITNDAATMLreLdIvHP

Chain	Residue	Details
Q	ILE64-PRO80
Z	LEU55-PRO71
B	VAL56-PRO72
A	VAL62-PRO78
D	ILE57-PRO73
G	LEU57-PRO73
H	ILE62-PRO78

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QKidMGDGT

Chain	Residue	Details
Q	GLN92-THR100
Z	GLN83-THR91
B	GLN84-THR92
A	GLN90-THR98
D	GLN85-THR93
E	GLN111-THR119
G	GLN85-THR93
H	GLN90-THR98

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"12872131","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)