Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7YFN

Core module of the NuA4 complex in S. cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000011	biological_process	vacuole inheritance
A	0000142	cellular_component	cellular bud neck contractile ring
A	0000166	molecular_function	nucleotide binding
A	0000785	cellular_component	chromatin
A	0000812	cellular_component	Swr1 complex
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005856	cellular_component	cytoskeleton
A	0005884	cellular_component	actin filament
A	0006281	biological_process	DNA repair
A	0006338	biological_process	chromatin remodeling
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006897	biological_process	endocytosis
A	0009306	biological_process	protein secretion
A	0015629	cellular_component	actin cytoskeleton
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030010	biological_process	establishment of cell polarity
A	0030476	biological_process	ascospore wall assembly
A	0030479	cellular_component	actin cortical patch
A	0031011	cellular_component	Ino80 complex
A	0032432	cellular_component	actin filament bundle
A	0035267	cellular_component	NuA4 histone acetyltransferase complex
A	0042802	molecular_function	identical protein binding
A	0071944	cellular_component	cell periphery
A	1902404	biological_process	mitotic actomyosin contractile ring contraction
B	0000785	cellular_component	chromatin
B	0000812	cellular_component	Swr1 complex
B	0003682	molecular_function	chromatin binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0006281	biological_process	DNA repair
B	0006325	biological_process	chromatin organization
B	0006338	biological_process	chromatin remodeling
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006974	biological_process	DNA damage response
B	0010468	biological_process	regulation of gene expression
B	0016514	cellular_component	SWI/SNF complex
B	0031011	cellular_component	Ino80 complex
B	0035267	cellular_component	NuA4 histone acetyltransferase complex
B	0042393	molecular_function	histone binding
B	0051382	biological_process	kinetochore assembly
D	0003674	molecular_function	molecular_function
D	0003682	molecular_function	chromatin binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0006281	biological_process	DNA repair
D	0006325	biological_process	chromatin organization
D	0006351	biological_process	DNA-templated transcription
D	0006974	biological_process	DNA damage response
D	0035267	cellular_component	NuA4 histone acetyltransferase complex
D	0065003	biological_process	protein-containing complex assembly
E	0000122	biological_process	negative regulation of transcription by RNA polymerase II
E	0000785	cellular_component	chromatin
E	0000812	cellular_component	Swr1 complex
E	0003714	molecular_function	transcription corepressor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005694	cellular_component	chromosome
E	0006281	biological_process	DNA repair
E	0006325	biological_process	chromatin organization
E	0006338	biological_process	chromatin remodeling
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006974	biological_process	DNA damage response
E	0035267	cellular_component	NuA4 histone acetyltransferase complex
E	0051276	biological_process	chromosome organization
F	0000786	cellular_component	nucleosome
F	0004402	molecular_function	histone acetyltransferase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0006281	biological_process	DNA repair
F	0006338	biological_process	chromatin remodeling
F	0006351	biological_process	DNA-templated transcription
F	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0006974	biological_process	DNA damage response
F	0016239	biological_process	positive regulation of macroautophagy
F	0032777	cellular_component	piccolo histone acetyltransferase complex
F	0035267	cellular_component	NuA4 histone acetyltransferase complex
T	0000124	cellular_component	SAGA complex
T	0004402	molecular_function	histone acetyltransferase activity
T	0004672	molecular_function	protein kinase activity
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0006281	biological_process	DNA repair
T	0006325	biological_process	chromatin organization
T	0006351	biological_process	DNA-templated transcription
T	0006355	biological_process	regulation of DNA-templated transcription
T	0006357	biological_process	regulation of transcription by RNA polymerase II
T	0033554	biological_process	cellular response to stress
T	0035267	cellular_component	NuA4 histone acetyltransferase complex
T	0045944	biological_process	positive regulation of transcription by RNA polymerase II
T	0046695	cellular_component	SLIK (SAGA-like) complex
T	0110078	cellular_component	TTT Hsp90 cochaperone complex
T	0140861	biological_process	DNA repair-dependent chromatin remodeling

Functional Information from PROSITE/UniProt

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
A	TYR53-GLY63

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
A	TRP356-GLU364

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApMNPksNR

Chain	Residue	Details
A	LEU104-ARG116
B	LEU109-ARG121

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Site: {"description":"Not methylated","evidences":[{"source":"PubMed","id":"10496983","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	62
Details	Domain: {"description":"Myb-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00133","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	39
Details	Repeat: {"description":"HEAT 13","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	38
Details	Repeat: {"description":"HEAT 14","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	37
Details	Repeat: {"description":"HEAT 15","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	37
Details	Repeat: {"description":"HEAT 27","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	32
Details	Domain: {"description":"FATC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00534","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00535","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	6
Details	Region: {"description":"G-loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	8
Details	Region: {"description":"Catalytic loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)