Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7YBU

Human propionyl-coenzyme A carboxylase

Functional Information from GO Data
ChainGOidnamespacecontents
A0004658molecular_functionpropionyl-CoA carboxylase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005739cellular_componentmitochondrion
A0005759cellular_componentmitochondrial matrix
A0005829cellular_componentcytosol
A0006631biological_processfatty acid metabolic process
A0009081biological_processbranched-chain amino acid metabolic process
A0009374molecular_functionbiotin binding
A0016885molecular_functionligase activity, forming carbon-carbon bonds
A0019626biological_processshort-chain fatty acid catabolic process
A0019899molecular_functionenzyme binding
A0046872molecular_functionmetal ion binding
A1901290biological_processsuccinyl-CoA biosynthetic process
A1902494cellular_componentcatalytic complex
B0004658molecular_functionpropionyl-CoA carboxylase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005739cellular_componentmitochondrion
B0005759cellular_componentmitochondrial matrix
B0005829cellular_componentcytosol
B0006631biological_processfatty acid metabolic process
B0009081biological_processbranched-chain amino acid metabolic process
B0009374molecular_functionbiotin binding
B0016885molecular_functionligase activity, forming carbon-carbon bonds
B0019626biological_processshort-chain fatty acid catabolic process
B0019899molecular_functionenzyme binding
B0046872molecular_functionmetal ion binding
B1901290biological_processsuccinyl-CoA biosynthetic process
B1902494cellular_componentcatalytic complex
C0004658molecular_functionpropionyl-CoA carboxylase activity
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005759cellular_componentmitochondrial matrix
C0005829cellular_componentcytosol
C0006631biological_processfatty acid metabolic process
C0009062biological_processfatty acid catabolic process
C0009081biological_processbranched-chain amino acid metabolic process
C0016874molecular_functionligase activity
C0019626biological_processshort-chain fatty acid catabolic process
C1902494cellular_componentcatalytic complex
D0004658molecular_functionpropionyl-CoA carboxylase activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005739cellular_componentmitochondrion
D0005759cellular_componentmitochondrial matrix
D0005829cellular_componentcytosol
D0006631biological_processfatty acid metabolic process
D0009081biological_processbranched-chain amino acid metabolic process
D0009374molecular_functionbiotin binding
D0016885molecular_functionligase activity, forming carbon-carbon bonds
D0019626biological_processshort-chain fatty acid catabolic process
D0019899molecular_functionenzyme binding
D0046872molecular_functionmetal ion binding
D1901290biological_processsuccinyl-CoA biosynthetic process
D1902494cellular_componentcatalytic complex
E0004658molecular_functionpropionyl-CoA carboxylase activity
E0005515molecular_functionprotein binding
E0005739cellular_componentmitochondrion
E0005759cellular_componentmitochondrial matrix
E0005829cellular_componentcytosol
E0006631biological_processfatty acid metabolic process
E0009062biological_processfatty acid catabolic process
E0009081biological_processbranched-chain amino acid metabolic process
E0016874molecular_functionligase activity
E0019626biological_processshort-chain fatty acid catabolic process
E1902494cellular_componentcatalytic complex
F0004658molecular_functionpropionyl-CoA carboxylase activity
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005739cellular_componentmitochondrion
F0005759cellular_componentmitochondrial matrix
F0005829cellular_componentcytosol
F0006631biological_processfatty acid metabolic process
F0009081biological_processbranched-chain amino acid metabolic process
F0009374molecular_functionbiotin binding
F0016885molecular_functionligase activity, forming carbon-carbon bonds
F0019626biological_processshort-chain fatty acid catabolic process
F0019899molecular_functionenzyme binding
F0046872molecular_functionmetal ion binding
F1901290biological_processsuccinyl-CoA biosynthetic process
F1902494cellular_componentcatalytic complex
G0004658molecular_functionpropionyl-CoA carboxylase activity
G0005515molecular_functionprotein binding
G0005739cellular_componentmitochondrion
G0005759cellular_componentmitochondrial matrix
G0005829cellular_componentcytosol
G0006631biological_processfatty acid metabolic process
G0009062biological_processfatty acid catabolic process
G0009081biological_processbranched-chain amino acid metabolic process
G0016874molecular_functionligase activity
G0019626biological_processshort-chain fatty acid catabolic process
G1902494cellular_componentcatalytic complex
H0004658molecular_functionpropionyl-CoA carboxylase activity
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005739cellular_componentmitochondrion
H0005759cellular_componentmitochondrial matrix
H0005829cellular_componentcytosol
H0006631biological_processfatty acid metabolic process
H0009081biological_processbranched-chain amino acid metabolic process
H0009374molecular_functionbiotin binding
H0016885molecular_functionligase activity, forming carbon-carbon bonds
H0019626biological_processshort-chain fatty acid catabolic process
H0019899molecular_functionenzyme binding
H0046872molecular_functionmetal ion binding
H1901290biological_processsuccinyl-CoA biosynthetic process
H1902494cellular_componentcatalytic complex
I0004658molecular_functionpropionyl-CoA carboxylase activity
I0005515molecular_functionprotein binding
I0005739cellular_componentmitochondrion
I0005759cellular_componentmitochondrial matrix
I0005829cellular_componentcytosol
I0006631biological_processfatty acid metabolic process
I0009062biological_processfatty acid catabolic process
I0009081biological_processbranched-chain amino acid metabolic process
I0016874molecular_functionligase activity
I0019626biological_processshort-chain fatty acid catabolic process
I1902494cellular_componentcatalytic complex
J0004658molecular_functionpropionyl-CoA carboxylase activity
J0005515molecular_functionprotein binding
J0005524molecular_functionATP binding
J0005739cellular_componentmitochondrion
J0005759cellular_componentmitochondrial matrix
J0005829cellular_componentcytosol
J0006631biological_processfatty acid metabolic process
J0009081biological_processbranched-chain amino acid metabolic process
J0009374molecular_functionbiotin binding
J0016885molecular_functionligase activity, forming carbon-carbon bonds
J0019626biological_processshort-chain fatty acid catabolic process
J0019899molecular_functionenzyme binding
J0046872molecular_functionmetal ion binding
J1901290biological_processsuccinyl-CoA biosynthetic process
J1902494cellular_componentcatalytic complex
K0004658molecular_functionpropionyl-CoA carboxylase activity
K0005515molecular_functionprotein binding
K0005739cellular_componentmitochondrion
K0005759cellular_componentmitochondrial matrix
K0005829cellular_componentcytosol
K0006631biological_processfatty acid metabolic process
K0009062biological_processfatty acid catabolic process
K0009081biological_processbranched-chain amino acid metabolic process
K0016874molecular_functionligase activity
K0019626biological_processshort-chain fatty acid catabolic process
K1902494cellular_componentcatalytic complex
P0004658molecular_functionpropionyl-CoA carboxylase activity
P0005515molecular_functionprotein binding
P0005739cellular_componentmitochondrion
P0005759cellular_componentmitochondrial matrix
P0005829cellular_componentcytosol
P0006631biological_processfatty acid metabolic process
P0009062biological_processfatty acid catabolic process
P0009081biological_processbranched-chain amino acid metabolic process
P0016874molecular_functionligase activity
P0019626biological_processshort-chain fatty acid catabolic process
P1902494cellular_componentcatalytic complex
Functional Information from PROSITE/UniProt
site_idPS00188
Number of Residues18
DetailsBIOTIN Biotin-requiring enzymes attachment site. GQeIcvIeAMKMqnsMtA
ChainResidueDetails
AGLY684-ALA701
site_idPS00866
Number of Residues15
DetailsCPSASE_1 Carbamoyl-phosphate synthase subdomain signature 1. YPVMIKASaggGGkG
ChainResidueDetails
ATYR214-GLY228
site_idPS00867
Number of Residues8
DetailsCPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. FLEMNTRL
ChainResidueDetails
APHE347-LEU354
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2682
DetailsDomain: {"description":"Biotin carboxylation","evidences":[{"source":"PROSITE-ProRule","id":"PRU00969","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues1182
DetailsDomain: {"description":"ATP-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU00409","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues450
DetailsDomain: {"description":"Biotinyl-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU01066","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues6
DetailsActive site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues18
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues384
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00409","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues6
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"Q5LUF3","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues24
DetailsModified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q91ZA3","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues42
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q91ZA3","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues6
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q91ZA3","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues6
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q91ZA3","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues6
DetailsModified residue: {"description":"N6-biotinyllysine; by HLCS","evidences":[{"source":"PROSITE-ProRule","id":"PRU01066","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20443544","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues1434
DetailsDomain: {"description":"CoA carboxyltransferase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01137","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues198
DetailsRegion: {"description":"Acyl-CoA binding","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues6
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues18
DetailsModified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q99MN9","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues6
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q99MN9","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

254587

PDB entries from 2026-06-03

PDB statisticsPDBj update infoContact PDBjnumon