7Y97
Crystal structure of CYP109B4 from Bacillus Sonorensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008395 | molecular_function | steroid hydroxylase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0006707 | biological_process | cholesterol catabolic process |
| B | 0008395 | molecular_function | steroid hydroxylase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
| B | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | ASN68 |
| A | THR245 |
| A | THR246 |
| A | LEU249 |
| A | PRO287 |
| A | ILE291 |
| A | ARG293 |
| A | LEU316 |
| A | GLY343 |
| A | PHE344 |
| A | GLY345 |
| A | MET83 |
| A | HIS349 |
| A | CYS351 |
| A | GLY353 |
| A | HOH606 |
| A | HOH630 |
| A | HOH650 |
| A | VAL84 |
| A | HIS91 |
| A | ARG95 |
| A | ILE146 |
| A | LEU238 |
| A | ALA241 |
| A | GLY242 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue HEM B 501 |
| Chain | Residue |
| B | ASN68 |
| B | MET83 |
| B | VAL84 |
| B | HIS91 |
| B | ARG95 |
| B | LEU237 |
| B | ALA241 |
| B | GLY242 |
| B | THR245 |
| B | THR246 |
| B | PRO287 |
| B | ARG293 |
| B | GLY343 |
| B | PHE344 |
| B | GLY345 |
| B | HIS349 |
| B | CYS351 |
| B | GLY353 |
| B | ALA357 |
| B | HOH602 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGIHFCLG |
| Chain | Residue | Details |
| A | PHE344-GLY353 |
