7Y18

Crystal structure of ribosomal ITS2 pre-rRNA processing complex from Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005730	cellular_component	nucleolus
A	0006363	biological_process	termination of RNA polymerase I transcription
A	0006364	biological_process	rRNA processing
A	0006396	biological_process	RNA processing
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0030874	cellular_component	nucleolar chromatin
A	0051731	molecular_function	polynucleotide 5'-hydroxyl-kinase activity
B	0000166	molecular_function	nucleotide binding
B	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0006363	biological_process	termination of RNA polymerase I transcription
B	0006364	biological_process	rRNA processing
B	0006396	biological_process	RNA processing
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0030874	cellular_component	nucleolar chromatin
B	0051731	molecular_function	polynucleotide 5'-hydroxyl-kinase activity
C	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C	0000460	biological_process	maturation of 5.8S rRNA
C	0000470	biological_process	maturation of LSU-rRNA
C	0004519	molecular_function	endonuclease activity
C	0004521	molecular_function	RNA endonuclease activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0006364	biological_process	rRNA processing
C	0030687	cellular_component	preribosome, large subunit precursor
C	0090730	cellular_component	Las1 complex
D	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0000460	biological_process	maturation of 5.8S rRNA
D	0000470	biological_process	maturation of LSU-rRNA
D	0004519	molecular_function	endonuclease activity
D	0004521	molecular_function	RNA endonuclease activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0006364	biological_process	rRNA processing
D	0030687	cellular_component	preribosome, large subunit precursor
D	0090730	cellular_component	Las1 complex
E	0000166	molecular_function	nucleotide binding
E	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005730	cellular_component	nucleolus
E	0006363	biological_process	termination of RNA polymerase I transcription
E	0006364	biological_process	rRNA processing
E	0006396	biological_process	RNA processing
E	0016301	molecular_function	kinase activity
E	0016740	molecular_function	transferase activity
E	0030874	cellular_component	nucleolar chromatin
E	0051731	molecular_function	polynucleotide 5'-hydroxyl-kinase activity
F	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F	0000460	biological_process	maturation of 5.8S rRNA
F	0000470	biological_process	maturation of LSU-rRNA
F	0004519	molecular_function	endonuclease activity
F	0004521	molecular_function	RNA endonuclease activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0006364	biological_process	rRNA processing
F	0030687	cellular_component	preribosome, large subunit precursor
F	0090730	cellular_component	Las1 complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---