7XZG

High resolution crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans complexed with NAD+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001968	molecular_function	fibronectin binding
A	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006006	biological_process	glucose metabolic process
A	0006096	biological_process	glycolytic process
A	0007160	biological_process	cell-matrix adhesion
A	0009277	cellular_component	fungal-type cell wall
A	0009986	cellular_component	cell surface
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0030312	cellular_component	external encapsulating structure
A	0030445	cellular_component	yeast-form cell wall
A	0030446	cellular_component	hyphal cell wall
A	0043236	molecular_function	laminin binding
A	0044406	biological_process	adhesion of symbiont to host
A	0050661	molecular_function	NADP binding
A	0050840	molecular_function	extracellular matrix binding
A	0051287	molecular_function	NAD binding
A	0051701	biological_process	biological process involved in interaction with host
A	0052553	biological_process	symbiont-mediated perturbation of host immune response
A	0062040	cellular_component	fungal biofilm matrix
A	0106139	cellular_component	symbiont cell surface
A	1903561	cellular_component	extracellular vesicle
B	0000166	molecular_function	nucleotide binding
B	0001968	molecular_function	fibronectin binding
B	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006006	biological_process	glucose metabolic process
B	0006096	biological_process	glycolytic process
B	0007160	biological_process	cell-matrix adhesion
B	0009277	cellular_component	fungal-type cell wall
B	0009986	cellular_component	cell surface
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0030312	cellular_component	external encapsulating structure
B	0030445	cellular_component	yeast-form cell wall
B	0030446	cellular_component	hyphal cell wall
B	0043236	molecular_function	laminin binding
B	0044406	biological_process	adhesion of symbiont to host
B	0050661	molecular_function	NADP binding
B	0050840	molecular_function	extracellular matrix binding
B	0051287	molecular_function	NAD binding
B	0051701	biological_process	biological process involved in interaction with host
B	0052553	biological_process	symbiont-mediated perturbation of host immune response
B	0062040	cellular_component	fungal biofilm matrix
B	0106139	cellular_component	symbiont cell surface
B	1903561	cellular_component	extracellular vesicle
C	0000166	molecular_function	nucleotide binding
C	0001968	molecular_function	fibronectin binding
C	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006006	biological_process	glucose metabolic process
C	0006096	biological_process	glycolytic process
C	0007160	biological_process	cell-matrix adhesion
C	0009277	cellular_component	fungal-type cell wall
C	0009986	cellular_component	cell surface
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0030312	cellular_component	external encapsulating structure
C	0030445	cellular_component	yeast-form cell wall
C	0030446	cellular_component	hyphal cell wall
C	0043236	molecular_function	laminin binding
C	0044406	biological_process	adhesion of symbiont to host
C	0050661	molecular_function	NADP binding
C	0050840	molecular_function	extracellular matrix binding
C	0051287	molecular_function	NAD binding
C	0051701	biological_process	biological process involved in interaction with host
C	0052553	biological_process	symbiont-mediated perturbation of host immune response
C	0062040	cellular_component	fungal biofilm matrix
C	0106139	cellular_component	symbiont cell surface
C	1903561	cellular_component	extracellular vesicle
D	0000166	molecular_function	nucleotide binding
D	0001968	molecular_function	fibronectin binding
D	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006006	biological_process	glucose metabolic process
D	0006096	biological_process	glycolytic process
D	0007160	biological_process	cell-matrix adhesion
D	0009277	cellular_component	fungal-type cell wall
D	0009986	cellular_component	cell surface
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0030312	cellular_component	external encapsulating structure
D	0030445	cellular_component	yeast-form cell wall
D	0030446	cellular_component	hyphal cell wall
D	0043236	molecular_function	laminin binding
D	0044406	biological_process	adhesion of symbiont to host
D	0050661	molecular_function	NADP binding
D	0050840	molecular_function	extracellular matrix binding
D	0051287	molecular_function	NAD binding
D	0051701	biological_process	biological process involved in interaction with host
D	0052553	biological_process	symbiont-mediated perturbation of host immune response
D	0062040	cellular_component	fungal biofilm matrix
D	0106139	cellular_component	symbiont cell surface
D	1903561	cellular_component	extracellular vesicle

Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
A	ALA149-LEU156

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