7XYY
TRIM E3 ubiquitin ligase WT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001778 | biological_process | plasma membrane repair |
| A | 0001786 | molecular_function | phosphatidylserine binding |
| A | 0003012 | biological_process | muscle system process |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006887 | biological_process | exocytosis |
| A | 0006900 | biological_process | vesicle budding from membrane |
| A | 0007517 | biological_process | muscle organ development |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0010832 | biological_process | negative regulation of myotube differentiation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0031435 | molecular_function | mitogen-activated protein kinase kinase kinase binding |
| A | 0031624 | molecular_function | ubiquitin conjugating enzyme binding |
| A | 0042383 | cellular_component | sarcolemma |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0043161 | biological_process | proteasome-mediated ubiquitin-dependent protein catabolic process |
| A | 0043569 | biological_process | negative regulation of insulin-like growth factor receptor signaling pathway |
| A | 0045087 | biological_process | innate immune response |
| A | 0046627 | biological_process | negative regulation of insulin receptor signaling pathway |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051260 | biological_process | protein homooligomerization |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
| B | 0001778 | biological_process | plasma membrane repair |
| B | 0001786 | molecular_function | phosphatidylserine binding |
| B | 0003012 | biological_process | muscle system process |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006887 | biological_process | exocytosis |
| B | 0006900 | biological_process | vesicle budding from membrane |
| B | 0007517 | biological_process | muscle organ development |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0010832 | biological_process | negative regulation of myotube differentiation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0031435 | molecular_function | mitogen-activated protein kinase kinase kinase binding |
| B | 0031624 | molecular_function | ubiquitin conjugating enzyme binding |
| B | 0042383 | cellular_component | sarcolemma |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0043161 | biological_process | proteasome-mediated ubiquitin-dependent protein catabolic process |
| B | 0043569 | biological_process | negative regulation of insulin-like growth factor receptor signaling pathway |
| B | 0045087 | biological_process | innate immune response |
| B | 0046627 | biological_process | negative regulation of insulin receptor signaling pathway |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051260 | biological_process | protein homooligomerization |
| B | 0061630 | molecular_function | ubiquitin protein ligase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CgHsFCraCL |
| Chain | Residue | Details |
| A | CYS29-LEU38 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 194 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PDB","id":"7XYY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XYZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00024","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"7XV2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XYY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XYZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00024","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"7XYZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"7XV2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XYY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XYZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7XZ2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00024","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"7XZ1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"Q6ZMU5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"A0JPQ4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
