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7XX6

Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)

Functional Information from GO Data
ChainGOidnamespacecontents
a0000786cellular_componentnucleosome
a0003677molecular_functionDNA binding
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005694cellular_componentchromosome
a0006325biological_processchromatin organization
a0008285biological_processnegative regulation of cell population proliferation
a0030527molecular_functionstructural constituent of chromatin
a0031492molecular_functionnucleosomal DNA binding
a0031507biological_processheterochromatin formation
a0043229cellular_componentintracellular organelle
a0043505cellular_componentCENP-A containing nucleosome
a0046982molecular_functionprotein heterodimerization activity
a0061644biological_processprotein localization to CENP-A containing chromatin
a0070062cellular_componentextracellular exosome
A0000786cellular_componentnucleosome
A0003677molecular_functionDNA binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005694cellular_componentchromosome
A0006325biological_processchromatin organization
A0006334biological_processnucleosome assembly
A0010467biological_processgene expression
A0016020cellular_componentmembrane
A0030527molecular_functionstructural constituent of chromatin
A0032200biological_processtelomere organization
A0032991cellular_componentprotein-containing complex
A0040029biological_processepigenetic regulation of gene expression
A0043229cellular_componentintracellular organelle
A0045296molecular_functioncadherin binding
A0046982molecular_functionprotein heterodimerization activity
A0070062cellular_componentextracellular exosome
b0000786cellular_componentnucleosome
b0001530molecular_functionlipopolysaccharide binding
b0002227biological_processinnate immune response in mucosa
b0003677molecular_functionDNA binding
b0005515molecular_functionprotein binding
b0005615cellular_componentextracellular space
b0005634cellular_componentnucleus
b0005654cellular_componentnucleoplasm
b0005694cellular_componentchromosome
b0005829cellular_componentcytosol
b0005886cellular_componentplasma membrane
b0006325biological_processchromatin organization
b0006334biological_processnucleosome assembly
b0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
b0019731biological_processantibacterial humoral response
b0030527molecular_functionstructural constituent of chromatin
b0031640biological_processkilling of cells of another organism
b0042742biological_processdefense response to bacterium
b0043229cellular_componentintracellular organelle
b0043505cellular_componentCENP-A containing nucleosome
b0046982molecular_functionprotein heterodimerization activity
b0050829biological_processdefense response to Gram-negative bacterium
b0050830biological_processdefense response to Gram-positive bacterium
b0061644biological_processprotein localization to CENP-A containing chromatin
b0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
B0000781cellular_componentchromosome, telomeric region
B0000786cellular_componentnucleosome
B0003677molecular_functionDNA binding
B0003723molecular_functionRNA binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005694cellular_componentchromosome
B0006325biological_processchromatin organization
B0006334biological_processnucleosome assembly
B0016020cellular_componentmembrane
B0030527molecular_functionstructural constituent of chromatin
B0032200biological_processtelomere organization
B0032991cellular_componentprotein-containing complex
B0043505cellular_componentCENP-A containing nucleosome
B0045653biological_processnegative regulation of megakaryocyte differentiation
B0046982molecular_functionprotein heterodimerization activity
B0061644biological_processprotein localization to CENP-A containing chromatin
B0070062cellular_componentextracellular exosome
C0000786cellular_componentnucleosome
C0003677molecular_functionDNA binding
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005694cellular_componentchromosome
C0006325biological_processchromatin organization
C0008285biological_processnegative regulation of cell population proliferation
C0030527molecular_functionstructural constituent of chromatin
C0031492molecular_functionnucleosomal DNA binding
C0031507biological_processheterochromatin formation
C0043229cellular_componentintracellular organelle
C0043505cellular_componentCENP-A containing nucleosome
C0046982molecular_functionprotein heterodimerization activity
C0061644biological_processprotein localization to CENP-A containing chromatin
C0070062cellular_componentextracellular exosome
D0000786cellular_componentnucleosome
D0001530molecular_functionlipopolysaccharide binding
D0002227biological_processinnate immune response in mucosa
D0003677molecular_functionDNA binding
D0005515molecular_functionprotein binding
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005694cellular_componentchromosome
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006325biological_processchromatin organization
D0006334biological_processnucleosome assembly
D0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
D0019731biological_processantibacterial humoral response
D0030527molecular_functionstructural constituent of chromatin
D0031640biological_processkilling of cells of another organism
D0042742biological_processdefense response to bacterium
D0043229cellular_componentintracellular organelle
D0043505cellular_componentCENP-A containing nucleosome
D0046982molecular_functionprotein heterodimerization activity
D0050829biological_processdefense response to Gram-negative bacterium
D0050830biological_processdefense response to Gram-positive bacterium
D0061644biological_processprotein localization to CENP-A containing chromatin
D0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
e0000786cellular_componentnucleosome
e0003677molecular_functionDNA binding
e0005515molecular_functionprotein binding
e0005576cellular_componentextracellular region
e0005634cellular_componentnucleus
e0005654cellular_componentnucleoplasm
e0005694cellular_componentchromosome
e0006325biological_processchromatin organization
e0006334biological_processnucleosome assembly
e0010467biological_processgene expression
e0016020cellular_componentmembrane
e0030527molecular_functionstructural constituent of chromatin
e0032200biological_processtelomere organization
e0032991cellular_componentprotein-containing complex
e0040029biological_processepigenetic regulation of gene expression
e0043229cellular_componentintracellular organelle
e0045296molecular_functioncadherin binding
e0046982molecular_functionprotein heterodimerization activity
e0070062cellular_componentextracellular exosome
E0000786cellular_componentnucleosome
E0003677molecular_functionDNA binding
E0005515molecular_functionprotein binding
E0005576cellular_componentextracellular region
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005694cellular_componentchromosome
E0006325biological_processchromatin organization
E0006334biological_processnucleosome assembly
E0010467biological_processgene expression
E0016020cellular_componentmembrane
E0030527molecular_functionstructural constituent of chromatin
E0032200biological_processtelomere organization
E0032991cellular_componentprotein-containing complex
E0040029biological_processepigenetic regulation of gene expression
E0043229cellular_componentintracellular organelle
E0045296molecular_functioncadherin binding
E0046982molecular_functionprotein heterodimerization activity
E0070062cellular_componentextracellular exosome
f0000781cellular_componentchromosome, telomeric region
f0000786cellular_componentnucleosome
f0003677molecular_functionDNA binding
f0003723molecular_functionRNA binding
f0005515molecular_functionprotein binding
f0005576cellular_componentextracellular region
f0005634cellular_componentnucleus
f0005654cellular_componentnucleoplasm
f0005694cellular_componentchromosome
f0006325biological_processchromatin organization
f0006334biological_processnucleosome assembly
f0016020cellular_componentmembrane
f0030527molecular_functionstructural constituent of chromatin
f0032200biological_processtelomere organization
f0032991cellular_componentprotein-containing complex
f0043505cellular_componentCENP-A containing nucleosome
f0045653biological_processnegative regulation of megakaryocyte differentiation
f0046982molecular_functionprotein heterodimerization activity
f0061644biological_processprotein localization to CENP-A containing chromatin
f0070062cellular_componentextracellular exosome
F0000781cellular_componentchromosome, telomeric region
F0000786cellular_componentnucleosome
F0003677molecular_functionDNA binding
F0003723molecular_functionRNA binding
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005694cellular_componentchromosome
F0006325biological_processchromatin organization
F0006334biological_processnucleosome assembly
F0016020cellular_componentmembrane
F0030527molecular_functionstructural constituent of chromatin
F0032200biological_processtelomere organization
F0032991cellular_componentprotein-containing complex
F0043505cellular_componentCENP-A containing nucleosome
F0045653biological_processnegative regulation of megakaryocyte differentiation
F0046982molecular_functionprotein heterodimerization activity
F0061644biological_processprotein localization to CENP-A containing chromatin
F0070062cellular_componentextracellular exosome
g0000786cellular_componentnucleosome
g0003677molecular_functionDNA binding
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005694cellular_componentchromosome
g0006325biological_processchromatin organization
g0008285biological_processnegative regulation of cell population proliferation
g0030527molecular_functionstructural constituent of chromatin
g0031492molecular_functionnucleosomal DNA binding
g0031507biological_processheterochromatin formation
g0043229cellular_componentintracellular organelle
g0043505cellular_componentCENP-A containing nucleosome
g0046982molecular_functionprotein heterodimerization activity
g0061644biological_processprotein localization to CENP-A containing chromatin
g0070062cellular_componentextracellular exosome
G0000786cellular_componentnucleosome
G0003677molecular_functionDNA binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005694cellular_componentchromosome
G0006325biological_processchromatin organization
G0008285biological_processnegative regulation of cell population proliferation
G0030527molecular_functionstructural constituent of chromatin
G0031492molecular_functionnucleosomal DNA binding
G0031507biological_processheterochromatin formation
G0043229cellular_componentintracellular organelle
G0043505cellular_componentCENP-A containing nucleosome
G0046982molecular_functionprotein heterodimerization activity
G0061644biological_processprotein localization to CENP-A containing chromatin
G0070062cellular_componentextracellular exosome
h0000786cellular_componentnucleosome
h0001530molecular_functionlipopolysaccharide binding
h0002227biological_processinnate immune response in mucosa
h0003677molecular_functionDNA binding
h0005515molecular_functionprotein binding
h0005615cellular_componentextracellular space
h0005634cellular_componentnucleus
h0005654cellular_componentnucleoplasm
h0005694cellular_componentchromosome
h0005829cellular_componentcytosol
h0005886cellular_componentplasma membrane
h0006325biological_processchromatin organization
h0006334biological_processnucleosome assembly
h0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
h0019731biological_processantibacterial humoral response
h0030527molecular_functionstructural constituent of chromatin
h0031640biological_processkilling of cells of another organism
h0042742biological_processdefense response to bacterium
h0043229cellular_componentintracellular organelle
h0043505cellular_componentCENP-A containing nucleosome
h0046982molecular_functionprotein heterodimerization activity
h0050829biological_processdefense response to Gram-negative bacterium
h0050830biological_processdefense response to Gram-positive bacterium
h0061644biological_processprotein localization to CENP-A containing chromatin
h0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
H0000786cellular_componentnucleosome
H0001530molecular_functionlipopolysaccharide binding
H0002227biological_processinnate immune response in mucosa
H0003677molecular_functionDNA binding
H0005515molecular_functionprotein binding
H0005615cellular_componentextracellular space
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005694cellular_componentchromosome
H0005829cellular_componentcytosol
H0005886cellular_componentplasma membrane
H0006325biological_processchromatin organization
H0006334biological_processnucleosome assembly
H0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
H0019731biological_processantibacterial humoral response
H0030527molecular_functionstructural constituent of chromatin
H0031640biological_processkilling of cells of another organism
H0042742biological_processdefense response to bacterium
H0043229cellular_componentintracellular organelle
H0043505cellular_componentCENP-A containing nucleosome
H0046982molecular_functionprotein heterodimerization activity
H0050829biological_processdefense response to Gram-negative bacterium
H0050830biological_processdefense response to Gram-positive bacterium
H0061644biological_processprotein localization to CENP-A containing chromatin
H0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
i0000786cellular_componentnucleosome
i0003677molecular_functionDNA binding
i0005515molecular_functionprotein binding
i0005576cellular_componentextracellular region
i0005634cellular_componentnucleus
i0005654cellular_componentnucleoplasm
i0005694cellular_componentchromosome
i0006325biological_processchromatin organization
i0006334biological_processnucleosome assembly
i0010467biological_processgene expression
i0016020cellular_componentmembrane
i0030527molecular_functionstructural constituent of chromatin
i0032200biological_processtelomere organization
i0032991cellular_componentprotein-containing complex
i0040029biological_processepigenetic regulation of gene expression
i0043229cellular_componentintracellular organelle
i0045296molecular_functioncadherin binding
i0046982molecular_functionprotein heterodimerization activity
i0070062cellular_componentextracellular exosome
j0000781cellular_componentchromosome, telomeric region
j0000786cellular_componentnucleosome
j0003677molecular_functionDNA binding
j0003723molecular_functionRNA binding
j0005515molecular_functionprotein binding
j0005576cellular_componentextracellular region
j0005634cellular_componentnucleus
j0005654cellular_componentnucleoplasm
j0005694cellular_componentchromosome
j0006325biological_processchromatin organization
j0006334biological_processnucleosome assembly
j0016020cellular_componentmembrane
j0030527molecular_functionstructural constituent of chromatin
j0032200biological_processtelomere organization
j0032991cellular_componentprotein-containing complex
j0043505cellular_componentCENP-A containing nucleosome
j0045653biological_processnegative regulation of megakaryocyte differentiation
j0046982molecular_functionprotein heterodimerization activity
j0061644biological_processprotein localization to CENP-A containing chromatin
j0070062cellular_componentextracellular exosome
k0000786cellular_componentnucleosome
k0003677molecular_functionDNA binding
k0005515molecular_functionprotein binding
k0005634cellular_componentnucleus
k0005694cellular_componentchromosome
k0006325biological_processchromatin organization
k0008285biological_processnegative regulation of cell population proliferation
k0030527molecular_functionstructural constituent of chromatin
k0031492molecular_functionnucleosomal DNA binding
k0031507biological_processheterochromatin formation
k0043229cellular_componentintracellular organelle
k0043505cellular_componentCENP-A containing nucleosome
k0046982molecular_functionprotein heterodimerization activity
k0061644biological_processprotein localization to CENP-A containing chromatin
k0070062cellular_componentextracellular exosome
K0000786cellular_componentnucleosome
K0003677molecular_functionDNA binding
K0005515molecular_functionprotein binding
K0005576cellular_componentextracellular region
K0005634cellular_componentnucleus
K0005654cellular_componentnucleoplasm
K0005694cellular_componentchromosome
K0006325biological_processchromatin organization
K0006334biological_processnucleosome assembly
K0010467biological_processgene expression
K0016020cellular_componentmembrane
K0030527molecular_functionstructural constituent of chromatin
K0032200biological_processtelomere organization
K0032991cellular_componentprotein-containing complex
K0040029biological_processepigenetic regulation of gene expression
K0043229cellular_componentintracellular organelle
K0045296molecular_functioncadherin binding
K0046982molecular_functionprotein heterodimerization activity
K0070062cellular_componentextracellular exosome
l0000786cellular_componentnucleosome
l0001530molecular_functionlipopolysaccharide binding
l0002227biological_processinnate immune response in mucosa
l0003677molecular_functionDNA binding
l0005515molecular_functionprotein binding
l0005615cellular_componentextracellular space
l0005634cellular_componentnucleus
l0005654cellular_componentnucleoplasm
l0005694cellular_componentchromosome
l0005829cellular_componentcytosol
l0005886cellular_componentplasma membrane
l0006325biological_processchromatin organization
l0006334biological_processnucleosome assembly
l0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
l0019731biological_processantibacterial humoral response
l0030527molecular_functionstructural constituent of chromatin
l0031640biological_processkilling of cells of another organism
l0042742biological_processdefense response to bacterium
l0043229cellular_componentintracellular organelle
l0043505cellular_componentCENP-A containing nucleosome
l0046982molecular_functionprotein heterodimerization activity
l0050829biological_processdefense response to Gram-negative bacterium
l0050830biological_processdefense response to Gram-positive bacterium
l0061644biological_processprotein localization to CENP-A containing chromatin
l0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
L0000781cellular_componentchromosome, telomeric region
L0000786cellular_componentnucleosome
L0003677molecular_functionDNA binding
L0003723molecular_functionRNA binding
L0005515molecular_functionprotein binding
L0005576cellular_componentextracellular region
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005694cellular_componentchromosome
L0006325biological_processchromatin organization
L0006334biological_processnucleosome assembly
L0016020cellular_componentmembrane
L0030527molecular_functionstructural constituent of chromatin
L0032200biological_processtelomere organization
L0032991cellular_componentprotein-containing complex
L0043505cellular_componentCENP-A containing nucleosome
L0045653biological_processnegative regulation of megakaryocyte differentiation
L0046982molecular_functionprotein heterodimerization activity
L0061644biological_processprotein localization to CENP-A containing chromatin
L0070062cellular_componentextracellular exosome
M0000786cellular_componentnucleosome
M0003677molecular_functionDNA binding
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005694cellular_componentchromosome
M0006325biological_processchromatin organization
M0008285biological_processnegative regulation of cell population proliferation
M0030527molecular_functionstructural constituent of chromatin
M0031492molecular_functionnucleosomal DNA binding
M0031507biological_processheterochromatin formation
M0043229cellular_componentintracellular organelle
M0043505cellular_componentCENP-A containing nucleosome
M0046982molecular_functionprotein heterodimerization activity
M0061644biological_processprotein localization to CENP-A containing chromatin
M0070062cellular_componentextracellular exosome
N0000786cellular_componentnucleosome
N0001530molecular_functionlipopolysaccharide binding
N0002227biological_processinnate immune response in mucosa
N0003677molecular_functionDNA binding
N0005515molecular_functionprotein binding
N0005615cellular_componentextracellular space
N0005634cellular_componentnucleus
N0005654cellular_componentnucleoplasm
N0005694cellular_componentchromosome
N0005829cellular_componentcytosol
N0005886cellular_componentplasma membrane
N0006325biological_processchromatin organization
N0006334biological_processnucleosome assembly
N0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
N0019731biological_processantibacterial humoral response
N0030527molecular_functionstructural constituent of chromatin
N0031640biological_processkilling of cells of another organism
N0042742biological_processdefense response to bacterium
N0043229cellular_componentintracellular organelle
N0043505cellular_componentCENP-A containing nucleosome
N0046982molecular_functionprotein heterodimerization activity
N0050829biological_processdefense response to Gram-negative bacterium
N0050830biological_processdefense response to Gram-positive bacterium
N0061644biological_processprotein localization to CENP-A containing chromatin
N0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
o0000785cellular_componentchromatin
o0000786cellular_componentnucleosome
o0000791cellular_componenteuchromatin
o0003677molecular_functionDNA binding
o0003680molecular_functionminor groove of adenine-thymine-rich DNA binding
o0003690molecular_functiondouble-stranded DNA binding
o0003723molecular_functionRNA binding
o0005515molecular_functionprotein binding
o0005634cellular_componentnucleus
o0005654cellular_componentnucleoplasm
o0005694cellular_componentchromosome
o0005794cellular_componentGolgi apparatus
o0006334biological_processnucleosome assembly
o0015629cellular_componentactin cytoskeleton
o0016604cellular_componentnuclear body
o0017053cellular_componenttranscription repressor complex
o0030261biological_processchromosome condensation
o0030527molecular_functionstructural constituent of chromatin
o0031490molecular_functionchromatin DNA binding
o0031491molecular_functionnucleosome binding
o0031492molecular_functionnucleosomal DNA binding
o0031507biological_processheterochromatin formation
o0045910biological_processnegative regulation of DNA recombination
o2000679biological_processpositive regulation of transcription regulatory region DNA binding
O0000786cellular_componentnucleosome
O0003677molecular_functionDNA binding
O0005515molecular_functionprotein binding
O0005576cellular_componentextracellular region
O0005634cellular_componentnucleus
O0005654cellular_componentnucleoplasm
O0005694cellular_componentchromosome
O0006325biological_processchromatin organization
O0006334biological_processnucleosome assembly
O0010467biological_processgene expression
O0016020cellular_componentmembrane
O0030527molecular_functionstructural constituent of chromatin
O0032200biological_processtelomere organization
O0032991cellular_componentprotein-containing complex
O0040029biological_processepigenetic regulation of gene expression
O0043229cellular_componentintracellular organelle
O0045296molecular_functioncadherin binding
O0046982molecular_functionprotein heterodimerization activity
O0070062cellular_componentextracellular exosome
p0000785cellular_componentchromatin
p0000786cellular_componentnucleosome
p0000791cellular_componenteuchromatin
p0003677molecular_functionDNA binding
p0003680molecular_functionminor groove of adenine-thymine-rich DNA binding
p0003690molecular_functiondouble-stranded DNA binding
p0003723molecular_functionRNA binding
p0005515molecular_functionprotein binding
p0005634cellular_componentnucleus
p0005654cellular_componentnucleoplasm
p0005694cellular_componentchromosome
p0005794cellular_componentGolgi apparatus
p0006334biological_processnucleosome assembly
p0015629cellular_componentactin cytoskeleton
p0016604cellular_componentnuclear body
p0017053cellular_componenttranscription repressor complex
p0030261biological_processchromosome condensation
p0030527molecular_functionstructural constituent of chromatin
p0031490molecular_functionchromatin DNA binding
p0031491molecular_functionnucleosome binding
p0031492molecular_functionnucleosomal DNA binding
p0031507biological_processheterochromatin formation
p0045910biological_processnegative regulation of DNA recombination
p2000679biological_processpositive regulation of transcription regulatory region DNA binding
P0000781cellular_componentchromosome, telomeric region
P0000786cellular_componentnucleosome
P0003677molecular_functionDNA binding
P0003723molecular_functionRNA binding
P0005515molecular_functionprotein binding
P0005576cellular_componentextracellular region
P0005634cellular_componentnucleus
P0005654cellular_componentnucleoplasm
P0005694cellular_componentchromosome
P0006325biological_processchromatin organization
P0006334biological_processnucleosome assembly
P0016020cellular_componentmembrane
P0030527molecular_functionstructural constituent of chromatin
P0032200biological_processtelomere organization
P0032991cellular_componentprotein-containing complex
P0043505cellular_componentCENP-A containing nucleosome
P0045653biological_processnegative regulation of megakaryocyte differentiation
P0046982molecular_functionprotein heterodimerization activity
P0061644biological_processprotein localization to CENP-A containing chromatin
P0070062cellular_componentextracellular exosome
Q0000786cellular_componentnucleosome
Q0003677molecular_functionDNA binding
Q0005515molecular_functionprotein binding
Q0005634cellular_componentnucleus
Q0005694cellular_componentchromosome
Q0006325biological_processchromatin organization
Q0008285biological_processnegative regulation of cell population proliferation
Q0030527molecular_functionstructural constituent of chromatin
Q0031492molecular_functionnucleosomal DNA binding
Q0031507biological_processheterochromatin formation
Q0043229cellular_componentintracellular organelle
Q0043505cellular_componentCENP-A containing nucleosome
Q0046982molecular_functionprotein heterodimerization activity
Q0061644biological_processprotein localization to CENP-A containing chromatin
Q0070062cellular_componentextracellular exosome
R0000786cellular_componentnucleosome
R0001530molecular_functionlipopolysaccharide binding
R0002227biological_processinnate immune response in mucosa
R0003677molecular_functionDNA binding
R0005515molecular_functionprotein binding
R0005615cellular_componentextracellular space
R0005634cellular_componentnucleus
R0005654cellular_componentnucleoplasm
R0005694cellular_componentchromosome
R0005829cellular_componentcytosol
R0005886cellular_componentplasma membrane
R0006325biological_processchromatin organization
R0006334biological_processnucleosome assembly
R0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
R0019731biological_processantibacterial humoral response
R0030527molecular_functionstructural constituent of chromatin
R0031640biological_processkilling of cells of another organism
R0042742biological_processdefense response to bacterium
R0043229cellular_componentintracellular organelle
R0043505cellular_componentCENP-A containing nucleosome
R0046982molecular_functionprotein heterodimerization activity
R0050829biological_processdefense response to Gram-negative bacterium
R0050830biological_processdefense response to Gram-positive bacterium
R0061644biological_processprotein localization to CENP-A containing chromatin
R0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
U0000786cellular_componentnucleosome
U0003677molecular_functionDNA binding
U0005515molecular_functionprotein binding
U0005576cellular_componentextracellular region
U0005634cellular_componentnucleus
U0005654cellular_componentnucleoplasm
U0005694cellular_componentchromosome
U0006325biological_processchromatin organization
U0006334biological_processnucleosome assembly
U0010467biological_processgene expression
U0016020cellular_componentmembrane
U0030527molecular_functionstructural constituent of chromatin
U0032200biological_processtelomere organization
U0032991cellular_componentprotein-containing complex
U0040029biological_processepigenetic regulation of gene expression
U0043229cellular_componentintracellular organelle
U0045296molecular_functioncadherin binding
U0046982molecular_functionprotein heterodimerization activity
U0070062cellular_componentextracellular exosome
V0000781cellular_componentchromosome, telomeric region
V0000786cellular_componentnucleosome
V0003677molecular_functionDNA binding
V0003723molecular_functionRNA binding
V0005515molecular_functionprotein binding
V0005576cellular_componentextracellular region
V0005634cellular_componentnucleus
V0005654cellular_componentnucleoplasm
V0005694cellular_componentchromosome
V0006325biological_processchromatin organization
V0006334biological_processnucleosome assembly
V0016020cellular_componentmembrane
V0030527molecular_functionstructural constituent of chromatin
V0032200biological_processtelomere organization
V0032991cellular_componentprotein-containing complex
V0043505cellular_componentCENP-A containing nucleosome
V0045653biological_processnegative regulation of megakaryocyte differentiation
V0046982molecular_functionprotein heterodimerization activity
V0061644biological_processprotein localization to CENP-A containing chromatin
V0070062cellular_componentextracellular exosome
W0000786cellular_componentnucleosome
W0003677molecular_functionDNA binding
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005694cellular_componentchromosome
W0006325biological_processchromatin organization
W0008285biological_processnegative regulation of cell population proliferation
W0030527molecular_functionstructural constituent of chromatin
W0031492molecular_functionnucleosomal DNA binding
W0031507biological_processheterochromatin formation
W0043229cellular_componentintracellular organelle
W0043505cellular_componentCENP-A containing nucleosome
W0046982molecular_functionprotein heterodimerization activity
W0061644biological_processprotein localization to CENP-A containing chromatin
W0070062cellular_componentextracellular exosome
X0000786cellular_componentnucleosome
X0001530molecular_functionlipopolysaccharide binding
X0002227biological_processinnate immune response in mucosa
X0003677molecular_functionDNA binding
X0005515molecular_functionprotein binding
X0005615cellular_componentextracellular space
X0005634cellular_componentnucleus
X0005654cellular_componentnucleoplasm
X0005694cellular_componentchromosome
X0005829cellular_componentcytosol
X0005886cellular_componentplasma membrane
X0006325biological_processchromatin organization
X0006334biological_processnucleosome assembly
X0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
X0019731biological_processantibacterial humoral response
X0030527molecular_functionstructural constituent of chromatin
X0031640biological_processkilling of cells of another organism
X0042742biological_processdefense response to bacterium
X0043229cellular_componentintracellular organelle
X0043505cellular_componentCENP-A containing nucleosome
X0046982molecular_functionprotein heterodimerization activity
X0050829biological_processdefense response to Gram-negative bacterium
X0050830biological_processdefense response to Gram-positive bacterium
X0061644biological_processprotein localization to CENP-A containing chromatin
X0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
Y0000786cellular_componentnucleosome
Y0003677molecular_functionDNA binding
Y0005515molecular_functionprotein binding
Y0005576cellular_componentextracellular region
Y0005634cellular_componentnucleus
Y0005654cellular_componentnucleoplasm
Y0005694cellular_componentchromosome
Y0006325biological_processchromatin organization
Y0006334biological_processnucleosome assembly
Y0010467biological_processgene expression
Y0016020cellular_componentmembrane
Y0030527molecular_functionstructural constituent of chromatin
Y0032200biological_processtelomere organization
Y0032991cellular_componentprotein-containing complex
Y0040029biological_processepigenetic regulation of gene expression
Y0043229cellular_componentintracellular organelle
Y0045296molecular_functioncadherin binding
Y0046982molecular_functionprotein heterodimerization activity
Y0070062cellular_componentextracellular exosome
Z0000781cellular_componentchromosome, telomeric region
Z0000786cellular_componentnucleosome
Z0003677molecular_functionDNA binding
Z0003723molecular_functionRNA binding
Z0005515molecular_functionprotein binding
Z0005576cellular_componentextracellular region
Z0005634cellular_componentnucleus
Z0005654cellular_componentnucleoplasm
Z0005694cellular_componentchromosome
Z0006325biological_processchromatin organization
Z0006334biological_processnucleosome assembly
Z0016020cellular_componentmembrane
Z0030527molecular_functionstructural constituent of chromatin
Z0032200biological_processtelomere organization
Z0032991cellular_componentprotein-containing complex
Z0043505cellular_componentCENP-A containing nucleosome
Z0045653biological_processnegative regulation of megakaryocyte differentiation
Z0046982molecular_functionprotein heterodimerization activity
Z0061644biological_processprotein localization to CENP-A containing chromatin
Z0070062cellular_componentextracellular exosome
Functional Information from PDB Data
site_idAC1
Number of Residues2
Detailsbinding site for residue CA C 201
ChainResidue
CGLU64
DVAL48

site_idAC2
Number of Residues1
Detailsbinding site for residue CA G 201
ChainResidue
GGLU41

site_idAC3
Number of Residues1
Detailsbinding site for residue CA I 101
ChainResidue
IDG-2

site_idAC4
Number of Residues2
Detailsbinding site for residue CA I 102
ChainResidue
IDG51
JDG-52

site_idAC5
Number of Residues2
Detailsbinding site for residue CA I 104
ChainResidue
IDG63
IDG64

site_idAC6
Number of Residues1
Detailsbinding site for residue CA I 105
ChainResidue
IDG-34

site_idAC7
Number of Residues2
Detailsbinding site for residue CA I 106
ChainResidue
IDG-52
JDG51

site_idAC8
Number of Residues2
Detailsbinding site for residue CA I 107
ChainResidue
IDG57
IDC58

site_idAC9
Number of Residues1
Detailsbinding site for residue CA I 108
ChainResidue
mDG32

site_idAD1
Number of Residues2
Detailsbinding site for residue K I 109
ChainResidue
IDT-26
IDA-25

site_idAD2
Number of Residues1
Detailsbinding site for residue CA J 101
ChainResidue
JDG29

site_idAD3
Number of Residues1
Detailsbinding site for residue CA J 103
ChainResidue
JDG-34

site_idAD4
Number of Residues3
Detailsbinding site for residue CA O 201
ChainResidue
OGLN76
OASP77
OCA202

site_idAD5
Number of Residues3
Detailsbinding site for residue CA O 202
ChainResidue
OGLU73
OCA201
PASP24

site_idAD6
Number of Residues2
Detailsbinding site for residue CA S 101
ChainResidue
SDG-52
TDG51

site_idAD7
Number of Residues1
Detailsbinding site for residue CA T 101
ChainResidue
TDG-19

site_idAD8
Number of Residues2
Detailsbinding site for residue CA T 102
ChainResidue
SDG-40
TDA39

site_idAD9
Number of Residues2
Detailsbinding site for residue K T 104
ChainResidue
TDT-26
TDA-25

site_idAE1
Number of Residues2
Detailsbinding site for residue K T 105
ChainResidue
TDT35
TDA36

site_idAE2
Number of Residues1
Detailsbinding site for residue CA a 201
ChainResidue
aGLU41

site_idAE3
Number of Residues1
Detailsbinding site for residue CA a 202
ChainResidue
aGLU91

site_idAE4
Number of Residues2
Detailsbinding site for residue CA c 101
ChainResidue
cDG51
dDG-52

site_idAE5
Number of Residues2
Detailsbinding site for residue CA c 102
ChainResidue
cDG-52
dDG51

site_idAE6
Number of Residues1
Detailsbinding site for residue CA c 104
ChainResidue
cDG63

site_idAE7
Number of Residues2
Detailsbinding site for residue CA c 105
ChainResidue
cDG57
cDC58

site_idAE8
Number of Residues1
Detailsbinding site for residue CA c 106
ChainResidue
cDG29

site_idAE9
Number of Residues1
Detailsbinding site for residue CA c 107
ChainResidue
cDG-2

site_idAF1
Number of Residues2
Detailsbinding site for residue K c 108
ChainResidue
cDT-26
cDA-25

site_idAF2
Number of Residues1
Detailsbinding site for residue CA d 103
ChainResidue
dDG29

site_idAF3
Number of Residues2
Detailsbinding site for residue CA d 107
ChainResidue
SDG32
dDC-50

site_idAF4
Number of Residues1
Detailsbinding site for residue CA d 108
ChainResidue
dDC-10

site_idAF5
Number of Residues1
Detailsbinding site for residue CA i 201
ChainResidue
iASP77

site_idAF6
Number of Residues1
Detailsbinding site for residue CA j 201
ChainResidue
jASP24

site_idAF7
Number of Residues1
Detailsbinding site for residue CA m 101
ChainResidue
mDG-53

site_idAF8
Number of Residues2
Detailsbinding site for residue CA m 102
ChainResidue
mDG62
mDG63

site_idAF9
Number of Residues3
Detailsbinding site for residue CA n 101
ChainResidue
mDG-52
nDG51
nDC52

site_idAG1
Number of Residues1
Detailsbinding site for residue CA o 201
ChainResidue
oGLU62

site_idAG2
Number of Residues1
Detailsbinding site for residue CA p 201
ChainResidue
pGLU62

Functional Information from PROSITE/UniProt
site_idPS00046
Number of Residues7
DetailsHISTONE_H2A Histone H2A signature. AGLqFPV
ChainResidueDetails
aALA21-VAL27

site_idPS00047
Number of Residues5
DetailsHISTONE_H4 Histone H4 signature. GAKRH
ChainResidueDetails
BGLY14-HIS18

site_idPS00322
Number of Residues7
DetailsHISTONE_H3_1 Histone H3 signature 1. KAPRKQL
ChainResidueDetails
ALYS14-LEU20

site_idPS00357
Number of Residues23
DetailsHISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG
ChainResidueDetails
bARG92-GLY114

site_idPS00959
Number of Residues9
DetailsHISTONE_H3_2 Histone H3 signature 2. PFqRLVREI
ChainResidueDetails
APRO66-ILE74

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylthreonine; partial; in Histone H1.0, N-terminally processed => ECO:0000269|PubMed:9582379, ECO:0007744|PubMed:19413330
ChainResidueDetails
oTHR2
pTHR2
NPRO1
RPRO1
XPRO1
bPRO1
hPRO1
lPRO1

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Deamidated asparagine; partial => ECO:0000269|PubMed:9582379
ChainResidueDetails
oASN4
pASN4
NGLU2
RGLU2
XGLU2
bGLU2
hGLU2
lGLU2

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Citrulline => ECO:0000250|UniProtKB:P43275
ChainResidueDetails
oARG42
HLYS11
HLYS15
HLYS16
HLYS20
HLYS23
HLYS43
HLYS85
NLYS5
NLYS11
NLYS15
pARG42
NLYS16
NLYS20
NLYS23
NLYS43
NLYS85
RLYS5
RLYS11
RLYS15
RLYS16
RLYS20
DLYS15
RLYS23
RLYS43
RLYS85
XLYS5
XLYS11
XLYS15
XLYS16
XLYS20
XLYS23
XLYS43
DLYS16
XLYS85
bLYS5
bLYS11
bLYS15
bLYS16
bLYS20
bLYS23
bLYS43
bLYS85
hLYS5
DLYS20
hLYS11
hLYS15
hLYS16
hLYS20
hLYS23
hLYS43
hLYS85
lLYS5
lLYS11
lLYS15
DLYS23
lLYS16
lLYS20
lLYS23
lLYS43
lLYS85
DLYS43
DLYS85
HLYS5

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: ADP-ribosylserine => ECO:0000269|PubMed:27723750
ChainResidueDetails
oSER104
WLYS95
aLYS9
aLYS95
gLYS9
gLYS95
kLYS9
kLYS95
pSER104
NSER6
RSER6
XSER6
bSER6
hSER6
lSER6
WLYS9

site_idSWS_FT_FI5
Number of Residues8
DetailsMOD_RES: N6-crotonyllysine; alternate => ECO:0000269|PubMed:21925322
ChainResidueDetails
DLYS12
PLYS8
PLYS16
PLYS44
VLYS8
VLYS16
VLYS44
ZLYS8
ZLYS16
ZLYS44
fLYS8
HLYS12
fLYS16
fLYS44
jLYS8
jLYS16
jLYS44
NLYS12
RLYS12
XLYS12
bLYS12
hLYS12
lLYS12
LLYS44

site_idSWS_FT_FI6
Number of Residues8
DetailsMOD_RES: Phosphoserine; by STK4/MST1 => ECO:0000269|PubMed:12757711
ChainResidueDetails
DSER14
LLYS31
LLYS77
LLYS91
PLYS12
PLYS31
PLYS77
PLYS91
VLYS12
VLYS31
VLYS77
HSER14
VLYS91
ZLYS12
ZLYS31
ZLYS77
ZLYS91
fLYS12
fLYS31
fLYS77
fLYS91
jLYS12
NSER14
jLYS31
jLYS77
jLYS91
RSER14
XSER14
bSER14
hSER14
lSER14
LLYS12

site_idSWS_FT_FI7
Number of Residues8
DetailsMOD_RES: N6-(2-hydroxyisobutyryl)lysine => ECO:0000269|PubMed:24681537
ChainResidueDetails
DLYS24
WLYS75
aLYS74
aLYS75
gLYS74
gLYS75
kLYS74
kLYS75
HLYS24
NLYS24
RLYS24
XLYS24
bLYS24
hLYS24
lLYS24
WLYS74

site_idSWS_FT_FI8
Number of Residues24
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435
ChainResidueDetails
DLYS34
RLYS34
RLYS116
RLYS120
XLYS34
XLYS116
XLYS120
bLYS34
bLYS116
bLYS120
hLYS34
DLYS116
hLYS116
hLYS120
lLYS34
lLYS116
lLYS120
DLYS120
HLYS34
HLYS116
HLYS120
NLYS34
NLYS116
NLYS120

site_idSWS_FT_FI9
Number of Residues8
DetailsMOD_RES: PolyADP-ribosyl glutamic acid => ECO:0000250|UniProtKB:Q64475
ChainResidueDetails
DGLU35
QLYS118
QLYS119
QLYS125
WLYS118
WLYS119
WLYS125
aLYS118
aLYS119
aLYS125
gLYS118
HGLU35
gLYS119
gLYS125
kLYS118
kLYS119
kLYS125
NGLU35
RGLU35
XGLU35
bGLU35
hGLU35
lGLU35
MLYS125

site_idSWS_FT_FI10
Number of Residues8
DetailsMOD_RES: Phosphoserine; by AMPK => ECO:0000250|UniProtKB:Q64475
ChainResidueDetails
DSER36
ULYS56
YLYS14
YLYS56
eLYS14
eLYS56
iLYS14
iLYS56
HSER36
NSER36
RSER36
XSER36
bSER36
hSER36
lSER36
ULYS14

site_idSWS_FT_FI11
Number of Residues16
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16627869
ChainResidueDetails
DLYS46
XLYS108
bLYS46
bLYS108
hLYS46
hLYS108
lLYS46
lLYS108
DLYS108
HLYS46
HLYS108
NLYS46
NLYS108
RLYS46
RLYS108
XLYS46

site_idSWS_FT_FI12
Number of Residues8
DetailsMOD_RES: N6-(2-hydroxyisobutyryl)lysine; alternate => ECO:0000269|PubMed:24681537
ChainResidueDetails
DLYS57
WLYS119
YLYS18
aLYS119
eLYS18
gLYS119
iLYS18
kLYS119
HLYS57
NLYS57
RLYS57
XLYS57
bLYS57
hLYS57
lLYS57
ULYS18

site_idSWS_FT_FI13
Number of Residues8
DetailsMOD_RES: Dimethylated arginine => ECO:0000250|UniProtKB:Q96A08
ChainResidueDetails
DARG79
HARG79
NARG79
RARG79
XARG79
bARG79
hARG79
lARG79

site_idSWS_FT_FI14
Number of Residues16
DetailsMOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:Q96A08
ChainResidueDetails
DARG86
XARG92
bARG86
bARG92
hARG86
hARG92
lARG86
lARG92
DARG92
HARG86
HARG92
NARG86
NARG92
RARG86
RARG92
XARG86

site_idSWS_FT_FI15
Number of Residues8
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q00729
ChainResidueDetails
DTHR115
VLYS91
ZLYS91
fLYS91
jLYS91
HTHR115
NTHR115
RTHR115
XTHR115
bTHR115
hTHR115
lTHR115

site_idSWS_FT_FI16
Number of Residues8
DetailsCARBOHYD: O-linked (GlcNAc) serine => ECO:0000250|UniProtKB:P62807
ChainResidueDetails
DSER112
PLYS20
PLYS59
PLYS79
VLYS20
VLYS59
VLYS79
ZLYS20
ZLYS59
ZLYS79
fLYS20
HSER112
fLYS59
fLYS79
jLYS20
jLYS59
jLYS79
NSER112
RSER112
XSER112
bSER112
hSER112
lSER112
LLYS79

site_idSWS_FT_FI17
Number of Residues8
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:P58876
ChainResidueDetails
DLYS5
HLYS5
NLYS5
RLYS5
XLYS5
bLYS5
hLYS5
lLYS5

site_idSWS_FT_FI18
Number of Residues16
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:16713563
ChainResidueDetails
ALYS37
XLYS120
bLYS120
hLYS120
lLYS120
DLYS120
KLYS37
HLYS120
ULYS37
NLYS120
eLYS37
RLYS120

site_idSWS_FT_FI19
Number of Residues8
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:Q5QNW6
ChainResidueDetails
DLYS20
HLYS20
NLYS20
RLYS20
XLYS20
bLYS20
hLYS20
lLYS20

site_idSWS_FT_FI20
Number of Residues8
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:21726816
ChainResidueDetails
DLYS34
HLYS34
NLYS34
RLYS34
XLYS34
bLYS34
hLYS34
lLYS34

site_idSWS_FT_FI21
Number of Residues8
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:29211711
ChainResidueDetails
ALYS79
ELYS79
KLYS79
OLYS79
ULYS79
YLYS79
eLYS79
iLYS79

site_idSWS_FT_FI22
Number of Residues8
DetailsMOD_RES: Phosphothreonine => ECO:0000269|PubMed:20850016
ChainResidueDetails
ATHR80
ETHR80
KTHR80
OTHR80
UTHR80
YTHR80
eTHR80
iTHR80

site_idSWS_FT_FI23
Number of Residues8
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P84243
ChainResidueDetails
ASER86
ESER86
KSER86
OSER86
USER86
YSER86
eSER86
iSER86

site_idSWS_FT_FI24
Number of Residues8
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
ATHR107
ETHR107
KTHR107
OTHR107
UTHR107
YTHR107
eTHR107
iTHR107

site_idSWS_FT_FI25
Number of Residues8
DetailsMOD_RES: N6-glutaryllysine; alternate => ECO:0000269|PubMed:31542297
ChainResidueDetails
ALYS115
ELYS115
KLYS115
OLYS115
ULYS115
YLYS115
eLYS115
iLYS115

site_idSWS_FT_FI26
Number of Residues8
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:27436229
ChainResidueDetails
ALYS122
ELYS122
KLYS122
OLYS122
ULYS122
YLYS122
eLYS122
iLYS122

site_idSWS_FT_FI27
Number of Residues8
DetailsLIPID: N6-decanoyllysine => ECO:0000269|PubMed:35939806
ChainResidueDetails
ALYS18
ELYS18
KLYS18
OLYS18
ULYS18
YLYS18
eLYS18
iLYS18

222624

PDB entries from 2024-07-17

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