7XV9

Crystal structure of the Human TR4 DNA-Binding Domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008270	molecular_function	zinc ion binding
A	0043565	molecular_function	sequence-specific DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0008270	molecular_function	zinc ion binding
B	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00031
Number of Residues	27
Details	NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CvvCg.Dkasgr.HYgavsCegCkgFFkR

Chain	Residue	Details
A	CYS117-ARG143

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	150
Details	DNA_BIND: Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407

Chain	Residue	Details
A	VAL114-SER189
B	VAL114-SER189

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site_id	SWS_FT_FI2
Number of Residues	88
Details	ZN_FING: NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407

Chain	Residue	Details
A	CYS117-CYS137
A	CYS153-CYS177
B	CYS117-CYS137
B	CYS153-CYS177

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