7XUN

Structure of ATP7B C983S/C985S/D1027A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0000166	molecular_function	nucleotide binding
A	0005215	molecular_function	transporter activity
A	0005375	molecular_function	copper ion transmembrane transporter activity
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005770	cellular_component	late endosome
A	0005794	cellular_component	Golgi apparatus
A	0005802	cellular_component	trans-Golgi network
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006812	biological_process	monoatomic cation transport
A	0006825	biological_process	copper ion transport
A	0006878	biological_process	intracellular copper ion homeostasis
A	0015677	biological_process	copper ion import
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
A	0031410	cellular_component	cytoplasmic vesicle
A	0032588	cellular_component	trans-Golgi network membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0043682	molecular_function	P-type divalent copper transporter activity
A	0046688	biological_process	response to copper ion
A	0046872	molecular_function	metal ion binding
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0051208	biological_process	sequestering of calcium ion
A	0060003	biological_process	copper ion export
A	0075523	biological_process	viral translational frameshifting
A	0140581	molecular_function	P-type monovalent copper transporter activity
A	1990961	biological_process	xenobiotic detoxification by transmembrane export across the plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS01047
Number of Residues	30
Details	HMA_1 Heavy-metal-associated domain. IlGMtCqSCvksIEdrIsnlkgiismk.VsL

Chain	Residue	Details
A	ILE64-LEU93
A	VAL149-LEU178
A	ILE263-LEU292
A	ILE365-LEU394
A	ILE494-LEU523
A	ILE570-LEU599

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	159
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	78
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	139
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Active site: {"description":"4-aspartylphosphate intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q64535","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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