7XUJ

Human SLC26A3 in complex with UK5099

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005452	molecular_function	solute:inorganic anion antiporter activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006820	biological_process	monoatomic anion transport
A	0008271	molecular_function	secondary active sulfate transmembrane transporter activity
A	0015106	molecular_function	bicarbonate transmembrane transporter activity
A	0015108	molecular_function	chloride transmembrane transporter activity
A	0015116	molecular_function	sulfate transmembrane transporter activity
A	0015297	molecular_function	antiporter activity
A	0015701	biological_process	bicarbonate transport
A	0016020	cellular_component	membrane
A	0016324	cellular_component	apical plasma membrane
A	0019531	molecular_function	oxalate transmembrane transporter activity
A	0019532	biological_process	oxalate transport
A	0031526	cellular_component	brush border membrane
A	0048240	biological_process	sperm capacitation
A	0051454	biological_process	intracellular pH elevation
A	0055085	biological_process	transmembrane transport
A	0060081	biological_process	membrane hyperpolarization
A	0071320	biological_process	cellular response to cAMP
A	0097225	cellular_component	sperm midpiece
A	0140900	molecular_function	chloride:bicarbonate antiporter activity
A	1902358	biological_process	sulfate transmembrane transport
A	1902476	biological_process	chloride transmembrane transport
B	0005452	molecular_function	solute:inorganic anion antiporter activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006820	biological_process	monoatomic anion transport
B	0008271	molecular_function	secondary active sulfate transmembrane transporter activity
B	0015106	molecular_function	bicarbonate transmembrane transporter activity
B	0015108	molecular_function	chloride transmembrane transporter activity
B	0015116	molecular_function	sulfate transmembrane transporter activity
B	0015297	molecular_function	antiporter activity
B	0015701	biological_process	bicarbonate transport
B	0016020	cellular_component	membrane
B	0016324	cellular_component	apical plasma membrane
B	0019531	molecular_function	oxalate transmembrane transporter activity
B	0019532	biological_process	oxalate transport
B	0031526	cellular_component	brush border membrane
B	0048240	biological_process	sperm capacitation
B	0051454	biological_process	intracellular pH elevation
B	0055085	biological_process	transmembrane transport
B	0060081	biological_process	membrane hyperpolarization
B	0071320	biological_process	cellular response to cAMP
B	0097225	cellular_component	sperm midpiece
B	0140900	molecular_function	chloride:bicarbonate antiporter activity
B	1902358	biological_process	sulfate transmembrane transport
B	1902476	biological_process	chloride transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS01130
Number of Residues	22
Details	SLC26A SLC26A transporters signature. PvYGLYASffpaIIYlffGTSR

Chain	Residue	Details
A	PRO102-ARG123

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	400
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	170
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	584
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	390
Details	Domain: {"description":"STAS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00198","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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