7XLB

Cryo-EM structure of human pannexin 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006812	biological_process	monoatomic cation transport
A	0015267	molecular_function	channel activity
A	0032732	biological_process	positive regulation of interleukin-1 production
B	0006812	biological_process	monoatomic cation transport
B	0015267	molecular_function	channel activity
B	0032732	biological_process	positive regulation of interleukin-1 production
C	0006812	biological_process	monoatomic cation transport
C	0015267	molecular_function	channel activity
C	0032732	biological_process	positive regulation of interleukin-1 production
D	0006812	biological_process	monoatomic cation transport
D	0015267	molecular_function	channel activity
D	0032732	biological_process	positive regulation of interleukin-1 production
E	0006812	biological_process	monoatomic cation transport
E	0015267	molecular_function	channel activity
E	0032732	biological_process	positive regulation of interleukin-1 production
F	0006812	biological_process	monoatomic cation transport
F	0015267	molecular_function	channel activity
F	0032732	biological_process	positive regulation of interleukin-1 production
G	0006812	biological_process	monoatomic cation transport
G	0015267	molecular_function	channel activity
G	0032732	biological_process	positive regulation of interleukin-1 production

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	616
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00351","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	364
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---