7XIF

Crystal structure of the aminopropyltransferase, SpeE from hyperthermophilic crenarchaeon, Pyrobaculum calidifontis in complex with 5'-methylthioadenosine (MTA) alone or together with spermidine or thermospermine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004766	molecular_function	spermidine synthase activity
A	0005737	cellular_component	cytoplasm
A	0006596	biological_process	polyamine biosynthetic process
A	0008295	biological_process	spermidine biosynthetic process
A	0010487	molecular_function	thermospermine synthase activity
A	0016740	molecular_function	transferase activity
B	0003824	molecular_function	catalytic activity
B	0004766	molecular_function	spermidine synthase activity
B	0005737	cellular_component	cytoplasm
B	0006596	biological_process	polyamine biosynthetic process
B	0008295	biological_process	spermidine biosynthetic process
B	0010487	molecular_function	thermospermine synthase activity
B	0016740	molecular_function	transferase activity
C	0003824	molecular_function	catalytic activity
C	0004766	molecular_function	spermidine synthase activity
C	0005737	cellular_component	cytoplasm
C	0006596	biological_process	polyamine biosynthetic process
C	0008295	biological_process	spermidine biosynthetic process
C	0010487	molecular_function	thermospermine synthase activity
C	0016740	molecular_function	transferase activity
D	0003824	molecular_function	catalytic activity
D	0004766	molecular_function	spermidine synthase activity
D	0005737	cellular_component	cytoplasm
D	0006596	biological_process	polyamine biosynthetic process
D	0008295	biological_process	spermidine biosynthetic process
D	0010487	molecular_function	thermospermine synthase activity
D	0016740	molecular_function	transferase activity
E	0003824	molecular_function	catalytic activity
E	0004766	molecular_function	spermidine synthase activity
E	0005737	cellular_component	cytoplasm
E	0006596	biological_process	polyamine biosynthetic process
E	0008295	biological_process	spermidine biosynthetic process
E	0010487	molecular_function	thermospermine synthase activity
E	0016740	molecular_function	transferase activity
F	0003824	molecular_function	catalytic activity
F	0004766	molecular_function	spermidine synthase activity
F	0005737	cellular_component	cytoplasm
F	0006596	biological_process	polyamine biosynthetic process
F	0008295	biological_process	spermidine biosynthetic process
F	0010487	molecular_function	thermospermine synthase activity
F	0016740	molecular_function	transferase activity
G	0003824	molecular_function	catalytic activity
G	0004766	molecular_function	spermidine synthase activity
G	0005737	cellular_component	cytoplasm
G	0006596	biological_process	polyamine biosynthetic process
G	0008295	biological_process	spermidine biosynthetic process
G	0010487	molecular_function	thermospermine synthase activity
G	0016740	molecular_function	transferase activity
H	0003824	molecular_function	catalytic activity
H	0004766	molecular_function	spermidine synthase activity
H	0005737	cellular_component	cytoplasm
H	0006596	biological_process	polyamine biosynthetic process
H	0008295	biological_process	spermidine biosynthetic process
H	0010487	molecular_function	thermospermine synthase activity
H	0016740	molecular_function	transferase activity
I	0003824	molecular_function	catalytic activity
I	0004766	molecular_function	spermidine synthase activity
I	0005737	cellular_component	cytoplasm
I	0006596	biological_process	polyamine biosynthetic process
I	0008295	biological_process	spermidine biosynthetic process
I	0010487	molecular_function	thermospermine synthase activity
I	0016740	molecular_function	transferase activity
J	0003824	molecular_function	catalytic activity
J	0004766	molecular_function	spermidine synthase activity
J	0005737	cellular_component	cytoplasm
J	0006596	biological_process	polyamine biosynthetic process
J	0008295	biological_process	spermidine biosynthetic process
J	0010487	molecular_function	thermospermine synthase activity
J	0016740	molecular_function	transferase activity
K	0003824	molecular_function	catalytic activity
K	0004766	molecular_function	spermidine synthase activity
K	0005737	cellular_component	cytoplasm
K	0006596	biological_process	polyamine biosynthetic process
K	0008295	biological_process	spermidine biosynthetic process
K	0010487	molecular_function	thermospermine synthase activity
K	0016740	molecular_function	transferase activity
L	0003824	molecular_function	catalytic activity
L	0004766	molecular_function	spermidine synthase activity
L	0005737	cellular_component	cytoplasm
L	0006596	biological_process	polyamine biosynthetic process
L	0008295	biological_process	spermidine biosynthetic process
L	0010487	molecular_function	thermospermine synthase activity
L	0016740	molecular_function	transferase activity

Functional Information from PROSITE/UniProt

site_id	PS01330
Number of Residues	14
Details	PABS_1 Polyamine biosynthesis (PABS) domain signature. VLILGGGeGatLrE

Chain	Residue	Details
A	VAL84-GLU97

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2880
Details	Domain: {"description":"PABS","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---