7XHL

Complex structure of a Glucose 6-Phosphate Dehydrogenase from Zymomonas mobilis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
A	0005829	cellular_component	cytosol
A	0006006	biological_process	glucose metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0009051	biological_process	pentose-phosphate shunt, oxidative branch
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0050661	molecular_function	NADP binding
B	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
B	0005829	cellular_component	cytosol
B	0006006	biological_process	glucose metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0009051	biological_process	pentose-phosphate shunt, oxidative branch
B	0016491	molecular_function	oxidoreductase activity
B	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
B	0050661	molecular_function	NADP binding
C	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
C	0005829	cellular_component	cytosol
C	0006006	biological_process	glucose metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0009051	biological_process	pentose-phosphate shunt, oxidative branch
C	0016491	molecular_function	oxidoreductase activity
C	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
C	0050661	molecular_function	NADP binding
D	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
D	0005829	cellular_component	cytosol
D	0006006	biological_process	glucose metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0009051	biological_process	pentose-phosphate shunt, oxidative branch
D	0016491	molecular_function	oxidoreductase activity
D	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
D	0050661	molecular_function	NADP binding
E	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
E	0005829	cellular_component	cytosol
E	0006006	biological_process	glucose metabolic process
E	0006098	biological_process	pentose-phosphate shunt
E	0009051	biological_process	pentose-phosphate shunt, oxidative branch
E	0016491	molecular_function	oxidoreductase activity
E	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
E	0050661	molecular_function	NADP binding
F	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
F	0005829	cellular_component	cytosol
F	0006006	biological_process	glucose metabolic process
F	0006098	biological_process	pentose-phosphate shunt
F	0009051	biological_process	pentose-phosphate shunt, oxidative branch
F	0016491	molecular_function	oxidoreductase activity
F	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
F	0050661	molecular_function	NADP binding
G	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
G	0005829	cellular_component	cytosol
G	0006006	biological_process	glucose metabolic process
G	0006098	biological_process	pentose-phosphate shunt
G	0009051	biological_process	pentose-phosphate shunt, oxidative branch
G	0016491	molecular_function	oxidoreductase activity
G	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
G	0050661	molecular_function	NADP binding
H	0004345	molecular_function	glucose-6-phosphate dehydrogenase activity
H	0005829	cellular_component	cytosol
H	0006006	biological_process	glucose metabolic process
H	0006098	biological_process	pentose-phosphate shunt
H	0009051	biological_process	pentose-phosphate shunt, oxidative branch
H	0016491	molecular_function	oxidoreductase activity
H	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
H	0050661	molecular_function	NADP binding

Functional Information from PROSITE/UniProt

site_id	PS00069
Number of Residues	7
Details	G6P_DEHYDROGENASE Glucose-6-phosphate dehydrogenase active site. DHYLGKE

Chain	Residue	Details
A	ASP173-GLU179

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00966

Chain	Residue	Details
A	HIS236
B	HIS236
C	HIS236
D	HIS236
E	HIS236
F	HIS236
G	HIS236
H	HIS236

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site_id	SWS_FT_FI2
Number of Residues	64
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00966

Chain	Residue	Details
A	ARG46
B	ASP89
B	LYS144
B	HIS174
B	LYS178
B	GLU212
B	ASP231
B	LYS334
C	ARG46
C	ASP89
C	LYS144
A	ASP89
C	HIS174
C	LYS178
C	GLU212
C	ASP231
C	LYS334
D	ARG46
D	ASP89
D	LYS144
D	HIS174
D	LYS178
A	LYS144
D	GLU212
D	ASP231
D	LYS334
E	ARG46
E	ASP89
E	LYS144
E	HIS174
E	LYS178
E	GLU212
E	ASP231
A	HIS174
E	LYS334
F	ARG46
F	ASP89
F	LYS144
F	HIS174
F	LYS178
F	GLU212
F	ASP231
F	LYS334
G	ARG46
A	LYS178
G	ASP89
G	LYS144
G	HIS174
G	LYS178
G	GLU212
G	ASP231
G	LYS334
H	ARG46
H	ASP89
H	LYS144
A	GLU212
H	HIS174
H	LYS178
H	GLU212
H	ASP231
H	LYS334
A	ASP231
A	LYS334
B	ARG46

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