7XGO

Human renin in complex with compound2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004190	molecular_function	aspartic-type endopeptidase activity
A	0006508	biological_process	proteolysis
B	0004190	molecular_function	aspartic-type endopeptidase activity
B	0006508	biological_process	proteolysis

Functional Information from PROSITE/UniProt

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVFDTGSSNVWV

Chain	Residue	Details
A	VAL35-VAL46
A	ALA223-GLY234

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:20927107

Chain	Residue	Details
A	ASP38
A	ASP226
B	ASP38
B	ASP226

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:2493678

Chain	Residue	Details
A	ASN5
A	ASN75
B	ASN5
B	ASN75

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