7X1J

Cryo-EM structure of human BTR1 in the outward-facing state in the presence of NH4Cl.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005272	molecular_function	sodium channel activity
A	0005372	molecular_function	water transmembrane transporter activity
A	0005452	molecular_function	solute:inorganic anion antiporter activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006814	biological_process	sodium ion transport
A	0006820	biological_process	monoatomic anion transport
A	0006833	biological_process	water transport
A	0012506	cellular_component	vesicle membrane
A	0015078	molecular_function	proton transmembrane transporter activity
A	0015106	molecular_function	bicarbonate transmembrane transporter activity
A	0015252	molecular_function	proton channel activity
A	0015293	molecular_function	symporter activity
A	0015297	molecular_function	antiporter activity
A	0015701	biological_process	bicarbonate transport
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0016324	cellular_component	apical plasma membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0030003	biological_process	intracellular monoatomic cation homeostasis
A	0034599	biological_process	cellular response to oxidative stress
A	0035445	biological_process	borate transmembrane transport
A	0035725	biological_process	sodium ion transmembrane transport
A	0042044	biological_process	fluid transport
A	0046713	biological_process	borate transport
A	0046715	molecular_function	active borate transmembrane transporter activity
A	0046983	molecular_function	protein dimerization activity
A	0050801	biological_process	monoatomic ion homeostasis
A	0051881	biological_process	regulation of mitochondrial membrane potential
A	0055085	biological_process	transmembrane transport
A	0071476	biological_process	cellular hypotonic response
A	1902600	biological_process	proton transmembrane transport
A	2000739	biological_process	regulation of mesenchymal stem cell differentiation
B	0005272	molecular_function	sodium channel activity
B	0005372	molecular_function	water transmembrane transporter activity
B	0005452	molecular_function	solute:inorganic anion antiporter activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006814	biological_process	sodium ion transport
B	0006820	biological_process	monoatomic anion transport
B	0006833	biological_process	water transport
B	0012506	cellular_component	vesicle membrane
B	0015078	molecular_function	proton transmembrane transporter activity
B	0015106	molecular_function	bicarbonate transmembrane transporter activity
B	0015252	molecular_function	proton channel activity
B	0015293	molecular_function	symporter activity
B	0015297	molecular_function	antiporter activity
B	0015701	biological_process	bicarbonate transport
B	0016020	cellular_component	membrane
B	0016323	cellular_component	basolateral plasma membrane
B	0016324	cellular_component	apical plasma membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0030003	biological_process	intracellular monoatomic cation homeostasis
B	0034599	biological_process	cellular response to oxidative stress
B	0035445	biological_process	borate transmembrane transport
B	0035725	biological_process	sodium ion transmembrane transport
B	0042044	biological_process	fluid transport
B	0046713	biological_process	borate transport
B	0046715	molecular_function	active borate transmembrane transporter activity
B	0046983	molecular_function	protein dimerization activity
B	0050801	biological_process	monoatomic ion homeostasis
B	0051881	biological_process	regulation of mitochondrial membrane potential
B	0055085	biological_process	transmembrane transport
B	0071476	biological_process	cellular hypotonic response
B	1902600	biological_process	proton transmembrane transport
B	2000739	biological_process	regulation of mesenchymal stem cell differentiation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	544
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	114
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"21288032","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	112
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"21288032","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---