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7X0X

Cryo-EM Structure of Arabidopsis CRY2 in active conformation

Functional Information from GO Data
ChainGOidnamespacecontents
A0000325cellular_componentplant-type vacuole
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0006139biological_processnucleobase-containing compound metabolic process
A0006325biological_processchromatin organization
A0006338biological_processchromatin remodeling
A0006950biological_processresponse to stress
A0006952biological_processdefense response
A0007623biological_processcircadian rhythm
A0009414biological_processresponse to water deprivation
A0009416biological_processresponse to light stimulus
A0009637biological_processresponse to blue light
A0009638biological_processphototropism
A0009646biological_processresponse to absence of light
A0009785biological_processblue light signaling pathway
A0009881molecular_functionphotoreceptor activity
A0009882molecular_functionblue light photoreceptor activity
A0009909biological_processregulation of flower development
A0009911biological_processpositive regulation of flower development
A0010075biological_processregulation of meristem growth
A0010118biological_processstomatal movement
A0010244biological_processresponse to low fluence blue light stimulus by blue low-fluence system
A0010617biological_processcircadian regulation of calcium ion oscillation
A0016301molecular_functionkinase activity
A0016604cellular_componentnuclear body
A0016605cellular_componentPML body
A0042752biological_processregulation of circadian rhythm
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0046777biological_processprotein autophosphorylation
A0046872molecular_functionmetal ion binding
A0048574biological_processlong-day photoperiodism, flowering
A0051607biological_processdefense response to virus
A0071949molecular_functionFAD binding
A0072387biological_processflavin adenine dinucleotide metabolic process
A0097159molecular_functionorganic cyclic compound binding
A1901371biological_processregulation of leaf morphogenesis
A1902347biological_processresponse to strigolactone
A2000028biological_processregulation of photoperiodism, flowering
A2000379biological_processpositive regulation of reactive oxygen species metabolic process
B0000325cellular_componentplant-type vacuole
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0006139biological_processnucleobase-containing compound metabolic process
B0006325biological_processchromatin organization
B0006338biological_processchromatin remodeling
B0006950biological_processresponse to stress
B0006952biological_processdefense response
B0007623biological_processcircadian rhythm
B0009414biological_processresponse to water deprivation
B0009416biological_processresponse to light stimulus
B0009637biological_processresponse to blue light
B0009638biological_processphototropism
B0009646biological_processresponse to absence of light
B0009785biological_processblue light signaling pathway
B0009881molecular_functionphotoreceptor activity
B0009882molecular_functionblue light photoreceptor activity
B0009909biological_processregulation of flower development
B0009911biological_processpositive regulation of flower development
B0010075biological_processregulation of meristem growth
B0010118biological_processstomatal movement
B0010244biological_processresponse to low fluence blue light stimulus by blue low-fluence system
B0010617biological_processcircadian regulation of calcium ion oscillation
B0016301molecular_functionkinase activity
B0016604cellular_componentnuclear body
B0016605cellular_componentPML body
B0042752biological_processregulation of circadian rhythm
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0046777biological_processprotein autophosphorylation
B0046872molecular_functionmetal ion binding
B0048574biological_processlong-day photoperiodism, flowering
B0051607biological_processdefense response to virus
B0071949molecular_functionFAD binding
B0072387biological_processflavin adenine dinucleotide metabolic process
B0097159molecular_functionorganic cyclic compound binding
B1901371biological_processregulation of leaf morphogenesis
B1902347biological_processresponse to strigolactone
B2000028biological_processregulation of photoperiodism, flowering
B2000379biological_processpositive regulation of reactive oxygen species metabolic process
C0000325cellular_componentplant-type vacuole
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0006139biological_processnucleobase-containing compound metabolic process
C0006325biological_processchromatin organization
C0006338biological_processchromatin remodeling
C0006950biological_processresponse to stress
C0006952biological_processdefense response
C0007623biological_processcircadian rhythm
C0009414biological_processresponse to water deprivation
C0009416biological_processresponse to light stimulus
C0009637biological_processresponse to blue light
C0009638biological_processphototropism
C0009646biological_processresponse to absence of light
C0009785biological_processblue light signaling pathway
C0009881molecular_functionphotoreceptor activity
C0009882molecular_functionblue light photoreceptor activity
C0009909biological_processregulation of flower development
C0009911biological_processpositive regulation of flower development
C0010075biological_processregulation of meristem growth
C0010118biological_processstomatal movement
C0010244biological_processresponse to low fluence blue light stimulus by blue low-fluence system
C0010617biological_processcircadian regulation of calcium ion oscillation
C0016301molecular_functionkinase activity
C0016604cellular_componentnuclear body
C0016605cellular_componentPML body
C0042752biological_processregulation of circadian rhythm
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0046777biological_processprotein autophosphorylation
C0046872molecular_functionmetal ion binding
C0048574biological_processlong-day photoperiodism, flowering
C0051607biological_processdefense response to virus
C0071949molecular_functionFAD binding
C0072387biological_processflavin adenine dinucleotide metabolic process
C0097159molecular_functionorganic cyclic compound binding
C1901371biological_processregulation of leaf morphogenesis
C1902347biological_processresponse to strigolactone
C2000028biological_processregulation of photoperiodism, flowering
C2000379biological_processpositive regulation of reactive oxygen species metabolic process
D0000325cellular_componentplant-type vacuole
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0006139biological_processnucleobase-containing compound metabolic process
D0006325biological_processchromatin organization
D0006338biological_processchromatin remodeling
D0006950biological_processresponse to stress
D0006952biological_processdefense response
D0007623biological_processcircadian rhythm
D0009414biological_processresponse to water deprivation
D0009416biological_processresponse to light stimulus
D0009637biological_processresponse to blue light
D0009638biological_processphototropism
D0009646biological_processresponse to absence of light
D0009785biological_processblue light signaling pathway
D0009881molecular_functionphotoreceptor activity
D0009882molecular_functionblue light photoreceptor activity
D0009909biological_processregulation of flower development
D0009911biological_processpositive regulation of flower development
D0010075biological_processregulation of meristem growth
D0010118biological_processstomatal movement
D0010244biological_processresponse to low fluence blue light stimulus by blue low-fluence system
D0010617biological_processcircadian regulation of calcium ion oscillation
D0016301molecular_functionkinase activity
D0016604cellular_componentnuclear body
D0016605cellular_componentPML body
D0042752biological_processregulation of circadian rhythm
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0046777biological_processprotein autophosphorylation
D0046872molecular_functionmetal ion binding
D0048574biological_processlong-day photoperiodism, flowering
D0051607biological_processdefense response to virus
D0071949molecular_functionFAD binding
D0072387biological_processflavin adenine dinucleotide metabolic process
D0097159molecular_functionorganic cyclic compound binding
D1901371biological_processregulation of leaf morphogenesis
D1902347biological_processresponse to strigolactone
D2000028biological_processregulation of photoperiodism, flowering
D2000379biological_processpositive regulation of reactive oxygen species metabolic process
Functional Information from PROSITE/UniProt
site_idPS00394
Number of Residues13
DetailsDNA_PHOTOLYASES_1_1 DNA photolyases class 1 signature 1. TGyPLVDAgMReL
ChainResidueDetails
DTHR336-LEU348

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues16
DetailsBINDING: BINDING => ECO:0000269|PubMed:32398826, ECO:0007744|PDB:6K8I, ECO:0007744|PDB:6K8K
ChainResidueDetails
DTYR232
DTHR244
DASN356
DASP387
BTYR232
BTHR244
BASN356
BASP387
CTYR232
CTHR244
CASN356
CASP387
ATYR232
ATHR244
AASN356
AASP387

site_idSWS_FT_FI2
Number of Residues16
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q43125
ChainResidueDetails
DASN235
DSER243
DHIS355
DASP406
BASN235
BSER243
BHIS355
BASP406
CASN235
CSER243
CHIS355
CASP406
AASN235
ASER243
AHIS355
AASP406

site_idSWS_FT_FI3
Number of Residues12
DetailsSITE: Involved in electron transfer from the protein surface to the FAD cofactor => ECO:0000269|PubMed:25428980
ChainResidueDetails
DTRP321
DALA374
DTRP397
BTRP321
BALA374
BTRP397
CTRP321
CALA374
CTRP397
ATRP321
AALA374
ATRP397

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphoserine; by CK1 => ECO:0000269|PubMed:23897926
ChainResidueDetails
DSER587
BSER587
CSER587
ASER587

site_idSWS_FT_FI5
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:25792146
ChainResidueDetails
DSER598
DSER599
DSER605
BSER598
BSER599
BSER605
CSER598
CSER599
CSER605
ASER598
ASER599
ASER605

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: Phosphothreonine; by CK1 => ECO:0000269|PubMed:23897926
ChainResidueDetails
DTHR603
BTHR603
CTHR603
ATHR603

219869

PDB entries from 2024-05-15

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