7WX3

GK domain of Drosophila P5CS filament with glutamate, ATP, and NADPH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004349	molecular_function	glutamate 5-kinase activity
A	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0006561	biological_process	proline biosynthetic process
A	0008652	biological_process	amino acid biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0055129	biological_process	L-proline biosynthetic process
B	0003824	molecular_function	catalytic activity
B	0004349	molecular_function	glutamate 5-kinase activity
B	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0006561	biological_process	proline biosynthetic process
B	0008652	biological_process	amino acid biosynthetic process
B	0016301	molecular_function	kinase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0055129	biological_process	L-proline biosynthetic process
C	0003824	molecular_function	catalytic activity
C	0004349	molecular_function	glutamate 5-kinase activity
C	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005759	cellular_component	mitochondrial matrix
C	0006561	biological_process	proline biosynthetic process
C	0008652	biological_process	amino acid biosynthetic process
C	0016301	molecular_function	kinase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0055129	biological_process	L-proline biosynthetic process
D	0003824	molecular_function	catalytic activity
D	0004349	molecular_function	glutamate 5-kinase activity
D	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0006561	biological_process	proline biosynthetic process
D	0008652	biological_process	amino acid biosynthetic process
D	0016301	molecular_function	kinase activity
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0055129	biological_process	L-proline biosynthetic process
E	0003824	molecular_function	catalytic activity
E	0004349	molecular_function	glutamate 5-kinase activity
E	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005759	cellular_component	mitochondrial matrix
E	0006561	biological_process	proline biosynthetic process
E	0008652	biological_process	amino acid biosynthetic process
E	0016301	molecular_function	kinase activity
E	0016491	molecular_function	oxidoreductase activity
E	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
E	0055129	biological_process	L-proline biosynthetic process
F	0003824	molecular_function	catalytic activity
F	0004349	molecular_function	glutamate 5-kinase activity
F	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005759	cellular_component	mitochondrial matrix
F	0006561	biological_process	proline biosynthetic process
F	0008652	biological_process	amino acid biosynthetic process
F	0016301	molecular_function	kinase activity
F	0016491	molecular_function	oxidoreductase activity
F	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
F	0055129	biological_process	L-proline biosynthetic process
G	0003824	molecular_function	catalytic activity
G	0004349	molecular_function	glutamate 5-kinase activity
G	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005759	cellular_component	mitochondrial matrix
G	0006561	biological_process	proline biosynthetic process
G	0008652	biological_process	amino acid biosynthetic process
G	0016301	molecular_function	kinase activity
G	0016491	molecular_function	oxidoreductase activity
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0055129	biological_process	L-proline biosynthetic process
H	0003824	molecular_function	catalytic activity
H	0004349	molecular_function	glutamate 5-kinase activity
H	0004350	molecular_function	glutamate-5-semialdehyde dehydrogenase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005759	cellular_component	mitochondrial matrix
H	0006561	biological_process	proline biosynthetic process
H	0008652	biological_process	amino acid biosynthetic process
H	0016301	molecular_function	kinase activity
H	0016491	molecular_function	oxidoreductase activity
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0055129	biological_process	L-proline biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00902
Number of Residues	18
Details	GLUTAMATE_5_KINASE Glutamate 5-kinase signature. SkvGtGGMdSKVkAAtwA

Chain	Residue	Details
A	SER288-ALA305

---

site_id	PS01223
Number of Residues	22
Details	PROA Gamma-glutamyl phosphate reductase signature. VpsldeAInHIhtYGSsHTDv.I

Chain	Residue	Details
A	VAL664-ILE685

---