7WWA

Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 2.5 hr in 20 mM Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005515	molecular_function	protein binding
A	0006203	biological_process	dGTP catabolic process
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0006289	biological_process	nucleotide-excision repair
A	0006974	biological_process	DNA damage response
A	0008413	molecular_function	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
A	0016787	molecular_function	hydrolase activity
A	0030145	molecular_function	manganese ion binding
A	0035539	molecular_function	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
A	0044715	molecular_function	8-oxo-dGDP phosphatase activity
A	0044716	molecular_function	8-oxo-GDP phosphatase activity
A	0046067	biological_process	dGDP catabolic process
A	0046872	molecular_function	metal ion binding
A	0047693	molecular_function	ATP diphosphatase activity

Functional Information from PROSITE/UniProt

site_id	PS00893
Number of Residues	22
Details	NUDIX_BOX Nudix box signature. GkiemgEtpeqAVvRELqEEvG

Chain	Residue	Details
A	GLY38-GLY59

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	128
Details	Domain: {"description":"Nudix hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19864691","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19864691","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12939141","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"19864691","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	21
Details	Motif: {"description":"Nudix box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---