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7WTN

Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Tsr1-1 (with Rps2)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
CA0000056biological_processribosomal small subunit export from nucleus
CA0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CA0000472biological_processendonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CA0003723molecular_functionRNA binding
CA0005634cellular_componentnucleus
CA0005730cellular_componentnucleolus
CA0005737cellular_componentcytoplasm
CA0030686cellular_component90S preribosome
CA0042134molecular_functionrRNA primary transcript binding
CA0042254biological_processribosome biogenesis
CA0042255biological_processribosome assembly
CA0043248biological_processproteasome assembly
CA0051082molecular_functionunfolded protein binding
CB0000056biological_processribosomal small subunit export from nucleus
CB0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CB0005515molecular_functionprotein binding
CB0005634cellular_componentnucleus
CB0005730cellular_componentnucleolus
CB0005737cellular_componentcytoplasm
CB0006364biological_processrRNA processing
CB0008168molecular_functionmethyltransferase activity
CB0008757molecular_functionS-adenosylmethionine-dependent methyltransferase activity
CB0016435molecular_functionrRNA (guanine) methyltransferase activity
CB0032259biological_processmethylation
CB0043527cellular_componenttRNA methyltransferase complex
CB0070476biological_processrRNA (guanine-N7)-methylation
SB0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SB0002181biological_processcytoplasmic translation
SB0003735molecular_functionstructural constituent of ribosome
SB0005737cellular_componentcytoplasm
SB0005829cellular_componentcytosol
SB0005840cellular_componentribosome
SB0006412biological_processtranslation
SB0022627cellular_componentcytosolic small ribosomal subunit
SB0030686cellular_component90S preribosome
SB1990904cellular_componentribonucleoprotein complex
SC0000054biological_processribosomal subunit export from nucleus
SC0002181biological_processcytoplasmic translation
SC0003723molecular_functionRNA binding
SC0003735molecular_functionstructural constituent of ribosome
SC0005515molecular_functionprotein binding
SC0005634cellular_componentnucleus
SC0005654cellular_componentnucleoplasm
SC0005730cellular_componentnucleolus
SC0005737cellular_componentcytoplasm
SC0005829cellular_componentcytosol
SC0005840cellular_componentribosome
SC0006364biological_processrRNA processing
SC0006412biological_processtranslation
SC0015935cellular_componentsmall ribosomal subunit
SC0022627cellular_componentcytosolic small ribosomal subunit
SC0032040cellular_componentsmall-subunit processome
SC0042254biological_processribosome biogenesis
SC0045903biological_processpositive regulation of translational fidelity
SC0070181molecular_functionsmall ribosomal subunit rRNA binding
SC1990904cellular_componentribonucleoprotein complex
SE0002181biological_processcytoplasmic translation
SE0003723molecular_functionRNA binding
SE0003735molecular_functionstructural constituent of ribosome
SE0005737cellular_componentcytoplasm
SE0005829cellular_componentcytosol
SE0005840cellular_componentribosome
SE0006412biological_processtranslation
SE0019843molecular_functionrRNA binding
SE0022627cellular_componentcytosolic small ribosomal subunit
SE0030686cellular_component90S preribosome
SE0032991cellular_componentprotein-containing complex
SE0043232cellular_componentintracellular non-membrane-bounded organelle
SE1990904cellular_componentribonucleoprotein complex
SG0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SG0003735molecular_functionstructural constituent of ribosome
SG0005634cellular_componentnucleus
SG0005654cellular_componentnucleoplasm
SG0005730cellular_componentnucleolus
SG0005737cellular_componentcytoplasm
SG0005829cellular_componentcytosol
SG0005840cellular_componentribosome
SG0006364biological_processrRNA processing
SG0006412biological_processtranslation
SG0022627cellular_componentcytosolic small ribosomal subunit
SG0030686cellular_component90S preribosome
SG0032040cellular_componentsmall-subunit processome
SG0042254biological_processribosome biogenesis
SG1990904cellular_componentribonucleoprotein complex
SH0002181biological_processcytoplasmic translation
SH0003735molecular_functionstructural constituent of ribosome
SH0005634cellular_componentnucleus
SH0005654cellular_componentnucleoplasm
SH0005730cellular_componentnucleolus
SH0005737cellular_componentcytoplasm
SH0005829cellular_componentcytosol
SH0005840cellular_componentribosome
SH0006364biological_processrRNA processing
SH0006412biological_processtranslation
SH0022627cellular_componentcytosolic small ribosomal subunit
SH0030686cellular_component90S preribosome
SH0032040cellular_componentsmall-subunit processome
SH0042254biological_processribosome biogenesis
SH0042274biological_processribosomal small subunit biogenesis
SH1990904cellular_componentribonucleoprotein complex
SI0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SI0003735molecular_functionstructural constituent of ribosome
SI0005737cellular_componentcytoplasm
SI0005829cellular_componentcytosol
SI0005840cellular_componentribosome
SI0006412biological_processtranslation
SI0022627cellular_componentcytosolic small ribosomal subunit
SI0030686cellular_component90S preribosome
SI1990904cellular_componentribonucleoprotein complex
SJ0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SJ0003723molecular_functionRNA binding
SJ0003735molecular_functionstructural constituent of ribosome
SJ0005515molecular_functionprotein binding
SJ0005634cellular_componentnucleus
SJ0005654cellular_componentnucleoplasm
SJ0005730cellular_componentnucleolus
SJ0005737cellular_componentcytoplasm
SJ0005829cellular_componentcytosol
SJ0005840cellular_componentribosome
SJ0006364biological_processrRNA processing
SJ0006412biological_processtranslation
SJ0015935cellular_componentsmall ribosomal subunit
SJ0019843molecular_functionrRNA binding
SJ0022627cellular_componentcytosolic small ribosomal subunit
SJ0030686cellular_component90S preribosome
SJ0032040cellular_componentsmall-subunit processome
SJ0042254biological_processribosome biogenesis
SJ0042274biological_processribosomal small subunit biogenesis
SJ0043226cellular_componentorganelle
SJ1990904cellular_componentribonucleoprotein complex
SL0000028biological_processribosomal small subunit assembly
SL0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SL0003735molecular_functionstructural constituent of ribosome
SL0005737cellular_componentcytoplasm
SL0005829cellular_componentcytosol
SL0005840cellular_componentribosome
SL0006412biological_processtranslation
SL0019843molecular_functionrRNA binding
SL0022627cellular_componentcytosolic small ribosomal subunit
SL0030686cellular_component90S preribosome
SL1990904cellular_componentribonucleoprotein complex
SN0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SN0002181biological_processcytoplasmic translation
SN0003735molecular_functionstructural constituent of ribosome
SN0005730cellular_componentnucleolus
SN0005737cellular_componentcytoplasm
SN0005829cellular_componentcytosol
SN0005840cellular_componentribosome
SN0006412biological_processtranslation
SN0022627cellular_componentcytosolic small ribosomal subunit
SN0030686cellular_component90S preribosome
SN0070181molecular_functionsmall ribosomal subunit rRNA binding
SN1990904cellular_componentribonucleoprotein complex
SO0000028biological_processribosomal small subunit assembly
SO0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SO0002181biological_processcytoplasmic translation
SO0003729molecular_functionmRNA binding
SO0003735molecular_functionstructural constituent of ribosome
SO0005634cellular_componentnucleus
SO0005654cellular_componentnucleoplasm
SO0005730cellular_componentnucleolus
SO0005737cellular_componentcytoplasm
SO0005829cellular_componentcytosol
SO0005840cellular_componentribosome
SO0006364biological_processrRNA processing
SO0006412biological_processtranslation
SO0022627cellular_componentcytosolic small ribosomal subunit
SO0030686cellular_component90S preribosome
SO0032040cellular_componentsmall-subunit processome
SO0042254biological_processribosome biogenesis
SO1990904cellular_componentribonucleoprotein complex
SW0002181biological_processcytoplasmic translation
SW0003735molecular_functionstructural constituent of ribosome
SW0005737cellular_componentcytoplasm
SW0005829cellular_componentcytosol
SW0005840cellular_componentribosome
SW0006412biological_processtranslation
SW0022627cellular_componentcytosolic small ribosomal subunit
SW1990904cellular_componentribonucleoprotein complex
SX0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SX0003735molecular_functionstructural constituent of ribosome
SX0005737cellular_componentcytoplasm
SX0005829cellular_componentcytosol
SX0005840cellular_componentribosome
SX0006412biological_processtranslation
SX0006450biological_processregulation of translational fidelity
SX0015935cellular_componentsmall ribosomal subunit
SX0022627cellular_componentcytosolic small ribosomal subunit
SX1990145biological_processmaintenance of translational fidelity
SX1990904cellular_componentribonucleoprotein complex
SY0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SY0002181biological_processcytoplasmic translation
SY0003735molecular_functionstructural constituent of ribosome
SY0005737cellular_componentcytoplasm
SY0005739cellular_componentmitochondrion
SY0005829cellular_componentcytosol
SY0005840cellular_componentribosome
SY0006412biological_processtranslation
SY0022627cellular_componentcytosolic small ribosomal subunit
SY1990904cellular_componentribonucleoprotein complex
Sb0000028biological_processribosomal small subunit assembly
Sb0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Sb0003723molecular_functionRNA binding
Sb0003735molecular_functionstructural constituent of ribosome
Sb0005737cellular_componentcytoplasm
Sb0005829cellular_componentcytosol
Sb0005840cellular_componentribosome
Sb0006412biological_processtranslation
Sb0008270molecular_functionzinc ion binding
Sb0022627cellular_componentcytosolic small ribosomal subunit
Sb0044391cellular_componentribosomal subunit
Sb0046872molecular_functionmetal ion binding
Sb1990904cellular_componentribonucleoprotein complex
Se0002181biological_processcytoplasmic translation
Se0003735molecular_functionstructural constituent of ribosome
Se0005737cellular_componentcytoplasm
Se0005829cellular_componentcytosol
Se0005840cellular_componentribosome
Se0006412biological_processtranslation
Se0010494cellular_componentcytoplasmic stress granule
Se0022627cellular_componentcytosolic small ribosomal subunit
Se1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR
ChainResidueDetails
SWGLY100-ARG117

site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD
ChainResidueDetails
SOLEU102-ASP124

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR
ChainResidueDetails
SXLYS62-ARG69

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS
ChainResidueDetails
SLGLY120-SER132

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY
ChainResidueDetails
SNVAL98-TYR128

site_idPS00528
Number of Residues15
DetailsRIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWlLdK
ChainResidueDetails
SEHIS8-LYS22

site_idPS00529
Number of Residues23
DetailsRIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKSvGFGlVYNSvaeakkfE
ChainResidueDetails
SYPHE64-GLU86

site_idPS00578
Number of Residues12
DetailsRIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM
ChainResidueDetails
SGILE52-MET63

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI
ChainResidueDetails
SCGLY93-ILE125

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI
ChainResidueDetails
SJLEU105-ILE129

site_idPS00948
Number of Residues14
DetailsRIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH
ChainResidueDetails
SHLYS76-HIS89

site_idPS01168
Number of Residues33
DetailsRIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStiLctPtG
ChainResidueDetails
SbLYS36-GLY68

site_idPS01191
Number of Residues13
DetailsRIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL
ChainResidueDetails
SBLEU61-LEU73

site_idPS01193
Number of Residues20
DetailsRIBOSOMAL_S8E Ribosomal protein S8e signature. RsaTGAkraqf.RkKrKfELG
ChainResidueDetails
SIARG11-GLY30

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0000269|PubMed:10601260, ECO:0000269|PubMed:1544921, ECO:0007744|PubMed:22814378
ChainResidueDetails
SLSER2

site_idSWS_FT_FI2
Number of Residues11
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
SLLYS15
SLLYS141
SLLYS148
SHLYS84
SLLYS46
SLLYS56
SLLYS57
SLLYS79
SLLYS96
SLLYS105
SLLYS133

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:19779198
ChainResidueDetails
SISER69
SISER73

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
SISER86
SISER154
SISER155
SISER161
SELYS168
SELYS174
SELYS179
SELYS211
SELYS233

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956
ChainResidueDetails
SITHR107

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
SISER158

226707

PDB entries from 2024-10-30

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