7WOT

Cryo-EM structure of the inner ring monomer of the Saccharomyces cerevisiae nuclear pore complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000055	biological_process	ribosomal large subunit export from nucleus
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005643	cellular_component	nuclear pore
A	0006606	biological_process	protein import into nucleus
A	0006913	biological_process	nucleocytoplasmic transport
A	0006999	biological_process	nuclear pore organization
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016973	biological_process	poly(A)+ mRNA export from nucleus
A	0017056	molecular_function	structural constituent of nuclear pore
A	0031965	cellular_component	nuclear membrane
A	0044612	cellular_component	nuclear pore linkers
A	0044615	cellular_component	nuclear pore nuclear basket
A	0051028	biological_process	mRNA transport
C	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
C	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
C	0003677	molecular_function	DNA binding
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005635	cellular_component	nuclear envelope
C	0005643	cellular_component	nuclear pore
C	0006405	biological_process	RNA export from nucleus
C	0006606	biological_process	protein import into nucleus
C	0006913	biological_process	nucleocytoplasmic transport
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0017056	molecular_function	structural constituent of nuclear pore
C	0031965	cellular_component	nuclear membrane
C	0036228	biological_process	protein localization to nuclear inner membrane
C	0044611	cellular_component	nuclear pore inner ring
C	0051028	biological_process	mRNA transport
C	0051292	biological_process	nuclear pore complex assembly
D	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
D	0003682	molecular_function	chromatin binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005635	cellular_component	nuclear envelope
D	0005643	cellular_component	nuclear pore
D	0006405	biological_process	RNA export from nucleus
D	0006606	biological_process	protein import into nucleus
D	0006913	biological_process	nucleocytoplasmic transport
D	0007059	biological_process	chromosome segregation
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0017056	molecular_function	structural constituent of nuclear pore
D	0031507	biological_process	heterochromatin formation
D	0031965	cellular_component	nuclear membrane
D	0034398	biological_process	telomere tethering at nuclear periphery
D	0036228	biological_process	protein localization to nuclear inner membrane
D	0044611	cellular_component	nuclear pore inner ring
D	0044877	molecular_function	protein-containing complex binding
D	0051028	biological_process	mRNA transport
D	0051292	biological_process	nuclear pore complex assembly
D	0099115	cellular_component	chromosome, subtelomeric region
D	1990841	molecular_function	promoter-specific chromatin binding
E	0005634	cellular_component	nucleus
E	0005635	cellular_component	nuclear envelope
E	0005643	cellular_component	nuclear pore
E	0006405	biological_process	RNA export from nucleus
E	0006606	biological_process	protein import into nucleus
E	0006913	biological_process	nucleocytoplasmic transport
E	0006999	biological_process	nuclear pore organization
E	0015031	biological_process	protein transport
E	0016020	cellular_component	membrane
E	0017056	molecular_function	structural constituent of nuclear pore
E	0031965	cellular_component	nuclear membrane
E	0031990	biological_process	mRNA export from nucleus in response to heat stress
E	0044611	cellular_component	nuclear pore inner ring
E	0051028	biological_process	mRNA transport
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005635	cellular_component	nuclear envelope
F	0005643	cellular_component	nuclear pore
F	0006913	biological_process	nucleocytoplasmic transport
F	0006999	biological_process	nuclear pore organization
F	0015031	biological_process	protein transport
F	0017056	molecular_function	structural constituent of nuclear pore
F	0044611	cellular_component	nuclear pore inner ring
F	0046822	biological_process	regulation of nucleocytoplasmic transport
F	0051028	biological_process	mRNA transport
G	0000055	biological_process	ribosomal large subunit export from nucleus
G	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005635	cellular_component	nuclear envelope
G	0005643	cellular_component	nuclear pore
G	0006405	biological_process	RNA export from nucleus
G	0006409	biological_process	tRNA export from nucleus
G	0006606	biological_process	protein import into nucleus
G	0006913	biological_process	nucleocytoplasmic transport
G	0008139	molecular_function	nuclear localization sequence binding
G	0015031	biological_process	protein transport
G	0016020	cellular_component	membrane
G	0016973	biological_process	poly(A)+ mRNA export from nucleus
G	0017056	molecular_function	structural constituent of nuclear pore
G	0031965	cellular_component	nuclear membrane
G	0034398	biological_process	telomere tethering at nuclear periphery
G	0042802	molecular_function	identical protein binding
G	0044613	cellular_component	nuclear pore central transport channel
G	0044614	cellular_component	nuclear pore cytoplasmic filaments
G	0051028	biological_process	mRNA transport
G	0140693	molecular_function	molecular condensate scaffold activity
G	1990000	biological_process	amyloid fibril formation
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005635	cellular_component	nuclear envelope
H	0005643	cellular_component	nuclear pore
H	0006606	biological_process	protein import into nucleus
H	0006607	biological_process	NLS-bearing protein import into nucleus
H	0006913	biological_process	nucleocytoplasmic transport
H	0006999	biological_process	nuclear pore organization
H	0015031	biological_process	protein transport
H	0016020	cellular_component	membrane
H	0017056	molecular_function	structural constituent of nuclear pore
H	0031965	cellular_component	nuclear membrane
H	0036228	biological_process	protein localization to nuclear inner membrane
H	0042802	molecular_function	identical protein binding
H	0044613	cellular_component	nuclear pore central transport channel
H	0051028	biological_process	mRNA transport
I	0000055	biological_process	ribosomal large subunit export from nucleus
I	0000056	biological_process	ribosomal small subunit export from nucleus
I	0005515	molecular_function	protein binding
I	0005543	molecular_function	phospholipid binding
I	0005634	cellular_component	nucleus
I	0005635	cellular_component	nuclear envelope
I	0005643	cellular_component	nuclear pore
I	0006405	biological_process	RNA export from nucleus
I	0006409	biological_process	tRNA export from nucleus
I	0006606	biological_process	protein import into nucleus
I	0006607	biological_process	NLS-bearing protein import into nucleus
I	0006913	biological_process	nucleocytoplasmic transport
I	0015031	biological_process	protein transport
I	0016020	cellular_component	membrane
I	0016973	biological_process	poly(A)+ mRNA export from nucleus
I	0017056	molecular_function	structural constituent of nuclear pore
I	0031965	cellular_component	nuclear membrane
I	0034399	cellular_component	nuclear periphery
I	0044613	cellular_component	nuclear pore central transport channel
I	0044615	cellular_component	nuclear pore nuclear basket
I	0051028	biological_process	mRNA transport
J	0000055	biological_process	ribosomal large subunit export from nucleus
J	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005635	cellular_component	nuclear envelope
J	0005643	cellular_component	nuclear pore
J	0006405	biological_process	RNA export from nucleus
J	0006409	biological_process	tRNA export from nucleus
J	0006606	biological_process	protein import into nucleus
J	0006913	biological_process	nucleocytoplasmic transport
J	0008139	molecular_function	nuclear localization sequence binding
J	0015031	biological_process	protein transport
J	0016020	cellular_component	membrane
J	0016973	biological_process	poly(A)+ mRNA export from nucleus
J	0017056	molecular_function	structural constituent of nuclear pore
J	0031965	cellular_component	nuclear membrane
J	0034398	biological_process	telomere tethering at nuclear periphery
J	0042802	molecular_function	identical protein binding
J	0044613	cellular_component	nuclear pore central transport channel
J	0044614	cellular_component	nuclear pore cytoplasmic filaments
J	0051028	biological_process	mRNA transport
J	0140693	molecular_function	molecular condensate scaffold activity
J	1990000	biological_process	amyloid fibril formation
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005635	cellular_component	nuclear envelope
K	0005643	cellular_component	nuclear pore
K	0006606	biological_process	protein import into nucleus
K	0006607	biological_process	NLS-bearing protein import into nucleus
K	0006913	biological_process	nucleocytoplasmic transport
K	0006999	biological_process	nuclear pore organization
K	0015031	biological_process	protein transport
K	0016020	cellular_component	membrane
K	0017056	molecular_function	structural constituent of nuclear pore
K	0031965	cellular_component	nuclear membrane
K	0036228	biological_process	protein localization to nuclear inner membrane
K	0042802	molecular_function	identical protein binding
K	0044613	cellular_component	nuclear pore central transport channel
K	0051028	biological_process	mRNA transport
L	0000055	biological_process	ribosomal large subunit export from nucleus
L	0000056	biological_process	ribosomal small subunit export from nucleus
L	0005515	molecular_function	protein binding
L	0005543	molecular_function	phospholipid binding
L	0005634	cellular_component	nucleus
L	0005635	cellular_component	nuclear envelope
L	0005643	cellular_component	nuclear pore
L	0006405	biological_process	RNA export from nucleus
L	0006409	biological_process	tRNA export from nucleus
L	0006606	biological_process	protein import into nucleus
L	0006607	biological_process	NLS-bearing protein import into nucleus
L	0006913	biological_process	nucleocytoplasmic transport
L	0015031	biological_process	protein transport
L	0016020	cellular_component	membrane
L	0016973	biological_process	poly(A)+ mRNA export from nucleus
L	0017056	molecular_function	structural constituent of nuclear pore
L	0031965	cellular_component	nuclear membrane
L	0034399	cellular_component	nuclear periphery
L	0044613	cellular_component	nuclear pore central transport channel
L	0044615	cellular_component	nuclear pore nuclear basket
L	0051028	biological_process	mRNA transport
M	0000055	biological_process	ribosomal large subunit export from nucleus
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005635	cellular_component	nuclear envelope
M	0005643	cellular_component	nuclear pore
M	0006606	biological_process	protein import into nucleus
M	0006913	biological_process	nucleocytoplasmic transport
M	0006999	biological_process	nuclear pore organization
M	0015031	biological_process	protein transport
M	0016020	cellular_component	membrane
M	0016973	biological_process	poly(A)+ mRNA export from nucleus
M	0017056	molecular_function	structural constituent of nuclear pore
M	0031965	cellular_component	nuclear membrane
M	0044612	cellular_component	nuclear pore linkers
M	0044615	cellular_component	nuclear pore nuclear basket
M	0051028	biological_process	mRNA transport
N	0000055	biological_process	ribosomal large subunit export from nucleus
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005635	cellular_component	nuclear envelope
N	0005643	cellular_component	nuclear pore
N	0006606	biological_process	protein import into nucleus
N	0006913	biological_process	nucleocytoplasmic transport
N	0006999	biological_process	nuclear pore organization
N	0015031	biological_process	protein transport
N	0016020	cellular_component	membrane
N	0016973	biological_process	poly(A)+ mRNA export from nucleus
N	0017056	molecular_function	structural constituent of nuclear pore
N	0031965	cellular_component	nuclear membrane
N	0044612	cellular_component	nuclear pore linkers
N	0044615	cellular_component	nuclear pore nuclear basket
N	0051028	biological_process	mRNA transport
O	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
O	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
O	0003677	molecular_function	DNA binding
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005635	cellular_component	nuclear envelope
O	0005643	cellular_component	nuclear pore
O	0006405	biological_process	RNA export from nucleus
O	0006606	biological_process	protein import into nucleus
O	0006913	biological_process	nucleocytoplasmic transport
O	0015031	biological_process	protein transport
O	0016020	cellular_component	membrane
O	0017056	molecular_function	structural constituent of nuclear pore
O	0031965	cellular_component	nuclear membrane
O	0036228	biological_process	protein localization to nuclear inner membrane
O	0044611	cellular_component	nuclear pore inner ring
O	0051028	biological_process	mRNA transport
O	0051292	biological_process	nuclear pore complex assembly
P	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
P	0003682	molecular_function	chromatin binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005635	cellular_component	nuclear envelope
P	0005643	cellular_component	nuclear pore
P	0006405	biological_process	RNA export from nucleus
P	0006606	biological_process	protein import into nucleus
P	0006913	biological_process	nucleocytoplasmic transport
P	0007059	biological_process	chromosome segregation
P	0015031	biological_process	protein transport
P	0016020	cellular_component	membrane
P	0017056	molecular_function	structural constituent of nuclear pore
P	0031507	biological_process	heterochromatin formation
P	0031965	cellular_component	nuclear membrane
P	0034398	biological_process	telomere tethering at nuclear periphery
P	0036228	biological_process	protein localization to nuclear inner membrane
P	0044611	cellular_component	nuclear pore inner ring
P	0044877	molecular_function	protein-containing complex binding
P	0051028	biological_process	mRNA transport
P	0051292	biological_process	nuclear pore complex assembly
P	0099115	cellular_component	chromosome, subtelomeric region
P	1990841	molecular_function	promoter-specific chromatin binding
Q	0005634	cellular_component	nucleus
Q	0005635	cellular_component	nuclear envelope
Q	0005643	cellular_component	nuclear pore
Q	0006405	biological_process	RNA export from nucleus
Q	0006606	biological_process	protein import into nucleus
Q	0006913	biological_process	nucleocytoplasmic transport
Q	0006999	biological_process	nuclear pore organization
Q	0015031	biological_process	protein transport
Q	0016020	cellular_component	membrane
Q	0017056	molecular_function	structural constituent of nuclear pore
Q	0031965	cellular_component	nuclear membrane
Q	0031990	biological_process	mRNA export from nucleus in response to heat stress
Q	0044611	cellular_component	nuclear pore inner ring
Q	0051028	biological_process	mRNA transport
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005635	cellular_component	nuclear envelope
R	0005643	cellular_component	nuclear pore
R	0006913	biological_process	nucleocytoplasmic transport
R	0006999	biological_process	nuclear pore organization
R	0015031	biological_process	protein transport
R	0017056	molecular_function	structural constituent of nuclear pore
R	0044611	cellular_component	nuclear pore inner ring
R	0046822	biological_process	regulation of nucleocytoplasmic transport
R	0051028	biological_process	mRNA transport
S	0000055	biological_process	ribosomal large subunit export from nucleus
S	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005635	cellular_component	nuclear envelope
S	0005643	cellular_component	nuclear pore
S	0006405	biological_process	RNA export from nucleus
S	0006409	biological_process	tRNA export from nucleus
S	0006606	biological_process	protein import into nucleus
S	0006913	biological_process	nucleocytoplasmic transport
S	0008139	molecular_function	nuclear localization sequence binding
S	0015031	biological_process	protein transport
S	0016020	cellular_component	membrane
S	0016973	biological_process	poly(A)+ mRNA export from nucleus
S	0017056	molecular_function	structural constituent of nuclear pore
S	0031965	cellular_component	nuclear membrane
S	0034398	biological_process	telomere tethering at nuclear periphery
S	0042802	molecular_function	identical protein binding
S	0044613	cellular_component	nuclear pore central transport channel
S	0044614	cellular_component	nuclear pore cytoplasmic filaments
S	0051028	biological_process	mRNA transport
S	0140693	molecular_function	molecular condensate scaffold activity
S	1990000	biological_process	amyloid fibril formation
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005635	cellular_component	nuclear envelope
T	0005643	cellular_component	nuclear pore
T	0006606	biological_process	protein import into nucleus
T	0006607	biological_process	NLS-bearing protein import into nucleus
T	0006913	biological_process	nucleocytoplasmic transport
T	0006999	biological_process	nuclear pore organization
T	0015031	biological_process	protein transport
T	0016020	cellular_component	membrane
T	0017056	molecular_function	structural constituent of nuclear pore
T	0031965	cellular_component	nuclear membrane
T	0036228	biological_process	protein localization to nuclear inner membrane
T	0042802	molecular_function	identical protein binding
T	0044613	cellular_component	nuclear pore central transport channel
T	0051028	biological_process	mRNA transport
U	0000055	biological_process	ribosomal large subunit export from nucleus
U	0000056	biological_process	ribosomal small subunit export from nucleus
U	0005515	molecular_function	protein binding
U	0005543	molecular_function	phospholipid binding
U	0005634	cellular_component	nucleus
U	0005635	cellular_component	nuclear envelope
U	0005643	cellular_component	nuclear pore
U	0006405	biological_process	RNA export from nucleus
U	0006409	biological_process	tRNA export from nucleus
U	0006606	biological_process	protein import into nucleus
U	0006607	biological_process	NLS-bearing protein import into nucleus
U	0006913	biological_process	nucleocytoplasmic transport
U	0015031	biological_process	protein transport
U	0016020	cellular_component	membrane
U	0016973	biological_process	poly(A)+ mRNA export from nucleus
U	0017056	molecular_function	structural constituent of nuclear pore
U	0031965	cellular_component	nuclear membrane
U	0034399	cellular_component	nuclear periphery
U	0044613	cellular_component	nuclear pore central transport channel
U	0044615	cellular_component	nuclear pore nuclear basket
U	0051028	biological_process	mRNA transport
V	0000055	biological_process	ribosomal large subunit export from nucleus
V	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
V	0003723	molecular_function	RNA binding
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005635	cellular_component	nuclear envelope
V	0005643	cellular_component	nuclear pore
V	0006405	biological_process	RNA export from nucleus
V	0006409	biological_process	tRNA export from nucleus
V	0006606	biological_process	protein import into nucleus
V	0006913	biological_process	nucleocytoplasmic transport
V	0008139	molecular_function	nuclear localization sequence binding
V	0015031	biological_process	protein transport
V	0016020	cellular_component	membrane
V	0016973	biological_process	poly(A)+ mRNA export from nucleus
V	0017056	molecular_function	structural constituent of nuclear pore
V	0031965	cellular_component	nuclear membrane
V	0034398	biological_process	telomere tethering at nuclear periphery
V	0042802	molecular_function	identical protein binding
V	0044613	cellular_component	nuclear pore central transport channel
V	0044614	cellular_component	nuclear pore cytoplasmic filaments
V	0051028	biological_process	mRNA transport
V	0140693	molecular_function	molecular condensate scaffold activity
V	1990000	biological_process	amyloid fibril formation
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005635	cellular_component	nuclear envelope
W	0005643	cellular_component	nuclear pore
W	0006606	biological_process	protein import into nucleus
W	0006607	biological_process	NLS-bearing protein import into nucleus
W	0006913	biological_process	nucleocytoplasmic transport
W	0006999	biological_process	nuclear pore organization
W	0015031	biological_process	protein transport
W	0016020	cellular_component	membrane
W	0017056	molecular_function	structural constituent of nuclear pore
W	0031965	cellular_component	nuclear membrane
W	0036228	biological_process	protein localization to nuclear inner membrane
W	0042802	molecular_function	identical protein binding
W	0044613	cellular_component	nuclear pore central transport channel
W	0051028	biological_process	mRNA transport
X	0000055	biological_process	ribosomal large subunit export from nucleus
X	0000056	biological_process	ribosomal small subunit export from nucleus
X	0005515	molecular_function	protein binding
X	0005543	molecular_function	phospholipid binding
X	0005634	cellular_component	nucleus
X	0005635	cellular_component	nuclear envelope
X	0005643	cellular_component	nuclear pore
X	0006405	biological_process	RNA export from nucleus
X	0006409	biological_process	tRNA export from nucleus
X	0006606	biological_process	protein import into nucleus
X	0006607	biological_process	NLS-bearing protein import into nucleus
X	0006913	biological_process	nucleocytoplasmic transport
X	0015031	biological_process	protein transport
X	0016020	cellular_component	membrane
X	0016973	biological_process	poly(A)+ mRNA export from nucleus
X	0017056	molecular_function	structural constituent of nuclear pore
X	0031965	cellular_component	nuclear membrane
X	0034399	cellular_component	nuclear periphery
X	0044613	cellular_component	nuclear pore central transport channel
X	0044615	cellular_component	nuclear pore nuclear basket
X	0051028	biological_process	mRNA transport
Z	0000055	biological_process	ribosomal large subunit export from nucleus
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005635	cellular_component	nuclear envelope
Z	0005643	cellular_component	nuclear pore
Z	0006606	biological_process	protein import into nucleus
Z	0006913	biological_process	nucleocytoplasmic transport
Z	0006999	biological_process	nuclear pore organization
Z	0015031	biological_process	protein transport
Z	0016020	cellular_component	membrane
Z	0016973	biological_process	poly(A)+ mRNA export from nucleus
Z	0017056	molecular_function	structural constituent of nuclear pore
Z	0031965	cellular_component	nuclear membrane
Z	0044612	cellular_component	nuclear pore linkers
Z	0044615	cellular_component	nuclear pore nuclear basket
Z	0051028	biological_process	mRNA transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
I	SER238
X	SER238
X	SER361
X	SER456
I	SER361
I	SER456
L	SER238
L	SER361
L	SER456
U	SER238
U	SER361
U	SER456

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
I	SER631
L	SER631
U	SER631
X	SER631

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