7WN0
Structure of PfENT1(Y190A) in complex with nanobody 19
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005337 | molecular_function | nucleoside transmembrane transporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006863 | biological_process | purine nucleobase transport |
| A | 0015858 | biological_process | nucleoside transport |
| A | 0016020 | cellular_component | membrane |
| A | 0032238 | biological_process | adenosine transport |
| A | 0055085 | biological_process | transmembrane transport |
| A | 1901642 | biological_process | nucleoside transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | MET1-SER31 | |
| A | VAL79-LYS87 | |
| A | THR144-MET149 | |
| A | LEU210-THR229 | |
| A | LEU296-SER308 | |
| A | GLU368-LYS374 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 273 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | SER32-GLY58 | |
| A | ILE340-LYS367 | |
| A | LYS375-ILE397 | |
| A | ASN62-ILE78 | |
| A | ILE88-PHE110 | |
| A | ASP113-SER143 | |
| A | GLY150-GLN173 | |
| A | LYS185-ASN209 | |
| A | LEU230-HIS269 | |
| A | ASP273-ASN295 | |
| A | LEU309-CYS331 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | LEU59-ILE61 | |
| A | PHE111-THR112 | |
| A | PHE174-ASN184 | |
| A | ASN270-SER272 | |
| A | VAL332-ASN339 | |
| A | TRP398-GLN422 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:36977719, ECO:0007744|PDB:7WN1 |
| Chain | Residue | Details |
| A | TRP53 | |
| A | GLN135 | |
| A | ASP287 | |
| A | ARG291 |
