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7WL2

Mouse Pendrin in bicarbonate and iodide buffer in inward state

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0006885biological_processregulation of pH
A0008271molecular_functionsecondary active sulfate transmembrane transporter activity
A0008509molecular_functionmonoatomic anion transmembrane transporter activity
A0009887biological_processanimal organ morphogenesis
A0015108molecular_functionchloride transmembrane transporter activity
A0015111molecular_functioniodide transmembrane transporter activity
A0015116molecular_functionsulfate transmembrane transporter activity
A0015698biological_processinorganic anion transport
A0015705biological_processiodide transport
A0016020cellular_componentmembrane
A0016324cellular_componentapical plasma membrane
A0019531molecular_functionoxalate transmembrane transporter activity
A0019532biological_processoxalate transport
A0031526cellular_componentbrush border membrane
A0032880biological_processregulation of protein localization
A0055085biological_processtransmembrane transport
A0070062cellular_componentextracellular exosome
A0140900molecular_functionchloride:bicarbonate antiporter activity
A1902358biological_processsulfate transmembrane transport
A1902476biological_processchloride transmembrane transport
B0005515molecular_functionprotein binding
B0005886cellular_componentplasma membrane
B0006885biological_processregulation of pH
B0008271molecular_functionsecondary active sulfate transmembrane transporter activity
B0008509molecular_functionmonoatomic anion transmembrane transporter activity
B0009887biological_processanimal organ morphogenesis
B0015108molecular_functionchloride transmembrane transporter activity
B0015111molecular_functioniodide transmembrane transporter activity
B0015116molecular_functionsulfate transmembrane transporter activity
B0015698biological_processinorganic anion transport
B0015705biological_processiodide transport
B0016020cellular_componentmembrane
B0016324cellular_componentapical plasma membrane
B0019531molecular_functionoxalate transmembrane transporter activity
B0019532biological_processoxalate transport
B0031526cellular_componentbrush border membrane
B0032880biological_processregulation of protein localization
B0055085biological_processtransmembrane transport
B0070062cellular_componentextracellular exosome
B0140900molecular_functionchloride:bicarbonate antiporter activity
B1902358biological_processsulfate transmembrane transport
B1902476biological_processchloride transmembrane transport
Functional Information from PROSITE/UniProt
site_idPS01130
Number of Residues22
DetailsSLC26A SLC26A transporters signature. VqFGLYSAffpiLTYfvfGTSR
ChainResidueDetails
AVAL113-ARG134

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues480
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues232
DetailsTopological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues84
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

243911

PDB entries from 2025-10-29

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