Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7WJZ

Omicron Spike bitrimer with 6m6 antibody

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0016020	cellular_component	membrane
B	0019031	cellular_component	viral envelope
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0039654	biological_process	fusion of virus membrane with host endosome membrane
B	0046813	biological_process	receptor-mediated virion attachment to host cell
B	0055036	cellular_component	virion membrane
B	0075509	biological_process	endocytosis involved in viral entry into host cell
I	0016020	cellular_component	membrane
I	0019031	cellular_component	viral envelope
I	0019064	biological_process	fusion of virus membrane with host plasma membrane
I	0039654	biological_process	fusion of virus membrane with host endosome membrane
I	0046813	biological_process	receptor-mediated virion attachment to host cell
I	0055036	cellular_component	virion membrane
I	0075509	biological_process	endocytosis involved in viral entry into host cell
J	0016020	cellular_component	membrane
J	0019031	cellular_component	viral envelope
J	0019064	biological_process	fusion of virus membrane with host plasma membrane
J	0039654	biological_process	fusion of virus membrane with host endosome membrane
J	0046813	biological_process	receptor-mediated virion attachment to host cell
J	0055036	cellular_component	virion membrane
J	0075509	biological_process	endocytosis involved in viral entry into host cell
K	0016020	cellular_component	membrane
K	0019031	cellular_component	viral envelope
K	0019064	biological_process	fusion of virus membrane with host plasma membrane
K	0039654	biological_process	fusion of virus membrane with host endosome membrane
K	0046813	biological_process	receptor-mediated virion attachment to host cell
K	0055036	cellular_component	virion membrane
K	0075509	biological_process	endocytosis involved in viral entry into host cell
L	0016020	cellular_component	membrane
L	0019031	cellular_component	viral envelope
L	0019064	biological_process	fusion of virus membrane with host plasma membrane
L	0039654	biological_process	fusion of virus membrane with host endosome membrane
L	0046813	biological_process	receptor-mediated virion attachment to host cell
L	0055036	cellular_component	virion membrane
L	0075509	biological_process	endocytosis involved in viral entry into host cell
M	0016020	cellular_component	membrane
M	0019031	cellular_component	viral envelope
M	0019064	biological_process	fusion of virus membrane with host plasma membrane
M	0039654	biological_process	fusion of virus membrane with host endosome membrane
M	0046813	biological_process	receptor-mediated virion attachment to host cell
M	0055036	cellular_component	virion membrane
M	0075509	biological_process	endocytosis involved in viral entry into host cell

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
C	TYR193-HIS199
A	TYR207-HIS213

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	SITE: Cleavage; by host furin => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32142651, ECO:0000269\|PubMed:32362314, ECO:0000269\|PubMed:32703818, ECO:0000269\|PubMed:34159616

Chain	Residue	Details
B	SER685
I	SER685
J	SER685
K	SER685
L	SER685
M	SER685

site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32703818, ECO:0000269\|PubMed:34159616

Chain	Residue	Details
B	ARG815
I	ARG815
J	ARG815
K	ARG815
L	ARG815
M	ARG815

site_id	SWS_FT_FI3
Number of Residues	18
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32366695, ECO:0000269\|PubMed:32979942

Chain	Residue	Details
B	ASN17
K	ASN17
K	ASN1158
K	ASN1173
L	ASN17
L	ASN1158
L	ASN1173
M	ASN17
M	ASN1158
M	ASN1173
B	ASN1158
B	ASN1173
I	ASN17
I	ASN1158
I	ASN1173
J	ASN17
J	ASN1158
J	ASN1173

site_id	SWS_FT_FI4
Number of Residues	30
Details	CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32155444, ECO:0000269\|PubMed:32363391, ECO:0000269\|PubMed:32366695, ECO:0000269\|PubMed:32979942

Chain	Residue	Details
B	ASN61
I	ASN1074
J	ASN61
J	THR124
J	ASN717
J	ASN801
J	ASN1074
K	ASN61
K	THR124
K	ASN717
K	ASN801
B	THR124
K	ASN1074
L	ASN61
L	THR124
L	ASN717
L	ASN801
L	ASN1074
M	ASN61
M	THR124
M	ASN717
M	ASN801
B	ASN717
M	ASN1074
B	ASN801
B	ASN1074
I	ASN61
I	THR124
I	ASN717
I	ASN801

site_id	SWS_FT_FI5
Number of Residues	18
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32363391, ECO:0000269\|PubMed:32366695, ECO:0000269\|PubMed:32979942

Chain	Residue	Details
B	THR76
K	THR76
K	GLU154
K	ASN1194
L	THR76
L	GLU154
L	ASN1194
M	THR76
M	GLU154
M	ASN1194
B	GLU154
B	ASN1194
I	THR76
I	GLU154
I	ASN1194
J	THR76
J	GLU154
J	ASN1194

site_id	SWS_FT_FI6
Number of Residues	42
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32155444, ECO:0000269\|PubMed:32363391, ECO:0000269\|PubMed:32366695, ECO:0000269\|PubMed:32979942

Chain	Residue	Details
B	TYR170
I	ASN331
I	ASN343
I	ASN616
I	ASN657
I	ASN1098
J	TYR170
J	ASN282
J	ASN331
J	ASN343
J	ASN616
B	ASN282
J	ASN657
J	ASN1098
K	TYR170
K	ASN282
K	ASN331
K	ASN343
K	ASN616
K	ASN657
K	ASN1098
L	TYR170
B	ASN331
L	ASN282
L	ASN331
L	ASN343
L	ASN616
L	ASN657
L	ASN1098
M	TYR170
M	ASN282
M	ASN331
M	ASN343
B	ASN343
M	ASN616
M	ASN657
M	ASN1098
B	ASN616
B	ASN657
B	ASN1098
I	TYR170
I	ASN282

site_id	SWS_FT_FI7
Number of Residues	12
Details	CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32155444, ECO:0000269\|PubMed:32363391, ECO:0000269\|PubMed:32366695, ECO:0000269\|PubMed:32979942

Chain	Residue	Details
B	ASN234
L	ASN709
M	ASN234
M	ASN709
B	ASN709
I	ASN234
I	ASN709
J	ASN234
J	ASN709
K	ASN234
K	ASN709
L	ASN234

site_id	SWS_FT_FI8
Number of Residues	6
Details	CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269\|PubMed:32363391

Chain	Residue	Details
B	THR323
I	THR323
J	THR323
K	THR323
L	THR323
M	THR323

site_id	SWS_FT_FI9
Number of Residues	6
Details	CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269\|PubMed:32363391

Chain	Residue	Details
B	SER325
I	SER325
J	SER325
K	SER325
L	SER325
M	SER325

site_id	SWS_FT_FI10
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32155444, ECO:0000269\|PubMed:32366695, ECO:0000269\|PubMed:32979942

Chain	Residue	Details
B	ASN603
I	ASN603
J	ASN603
K	ASN603
L	ASN603
M	ASN603

site_id	SWS_FT_FI11
Number of Residues	12
Details	CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269\|PubMed:34732583

Chain	Residue	Details
B	THR676
L	THR678
M	THR676
M	THR678
B	THR678
I	THR676
I	THR678
J	THR676
J	THR678
K	THR676
K	THR678
L	THR676

site_id	SWS_FT_FI12
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255\|HAMAP-Rule:MF_04099, ECO:0000269\|PubMed:32155444, ECO:0000269\|PubMed:32366695, ECO:0000269\|PubMed:32979942

Chain	Residue	Details
B	ASN1134
I	ASN1134
J	ASN1134
K	ASN1134
L	ASN1134
M	ASN1134

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)