7WE9
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv289
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0019031 | cellular_component | viral envelope |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| A | 0055036 | cellular_component | virion membrane |
| A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| B | 0016020 | cellular_component | membrane |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0055036 | cellular_component | virion membrane |
| B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| F | 0016020 | cellular_component | membrane |
| F | 0019031 | cellular_component | viral envelope |
| F | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| F | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| F | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| F | 0055036 | cellular_component | virion membrane |
| F | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3597 |
| Details | TOPO_DOM: Extracellular => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| A | GLN14-ILE1213 | |
| B | GLN14-ILE1213 | |
| F | GLN14-ILE1213 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| A | TRP1211-LEU1231 | |
| B | TRP1211-LEU1231 | |
| F | TRP1211-LEU1231 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 114 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| A | CYS1232-THR1270 | |
| B | CYS1232-THR1270 | |
| F | CYS1232-THR1270 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | ARG682 | |
| B | ARG682 | |
| F | ARG682 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | ARG812 | |
| B | ARG812 | |
| F | ARG812 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 15 |
| Details | LIPID: S-palmitoyl cysteine; by host ZDHHC20 => ECO:0000269|PubMed:34599882 |
| Chain | Residue | Details |
| A | CYS1232 | |
| B | CYS1240 | |
| F | CYS1232 | |
| F | CYS1233 | |
| F | CYS1237 | |
| F | CYS1238 | |
| F | CYS1240 | |
| A | CYS1233 | |
| A | CYS1237 | |
| A | CYS1238 | |
| A | CYS1240 | |
| B | CYS1232 | |
| B | CYS1233 | |
| B | CYS1237 | |
| B | CYS1238 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 15 |
| Details | LIPID: S-palmitoyl cysteine; by host ZDHHC20; partial => ECO:0000269|PubMed:34599882 |
| Chain | Residue | Details |
| A | CYS1244 | |
| B | CYS1251 | |
| F | CYS1244 | |
| F | CYS1245 | |
| F | CYS1247 | |
| F | CYS1250 | |
| F | CYS1251 | |
| A | CYS1245 | |
| A | CYS1247 | |
| A | CYS1250 | |
| A | CYS1251 | |
| B | CYS1244 | |
| B | CYS1245 | |
| B | CYS1247 | |
| B | CYS1250 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN17 | |
| A | ASN1155 | |
| A | ASN1170 | |
| B | ASN17 | |
| B | ASN1155 | |
| B | ASN1170 | |
| F | ASN17 | |
| F | ASN1155 | |
| F | ASN1170 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 15 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN61 | |
| B | ASN1071 | |
| F | ASN61 | |
| F | THR122 | |
| F | ASN714 | |
| F | ASN798 | |
| F | ASN1071 | |
| A | THR122 | |
| A | ASN714 | |
| A | ASN798 | |
| A | ASN1071 | |
| B | ASN61 | |
| B | THR122 | |
| B | ASN714 | |
| B | ASN798 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | THR74 | |
| A | GLU149 | |
| A | ASN1191 | |
| B | THR74 | |
| B | GLU149 | |
| B | ASN1191 | |
| F | THR74 | |
| F | GLU149 | |
| F | ASN1191 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 21 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | TYR165 | |
| B | ASN328 | |
| B | ASN340 | |
| B | ASN613 | |
| B | ASN654 | |
| B | ASN1095 | |
| F | TYR165 | |
| F | ASN279 | |
| F | ASN328 | |
| F | ASN340 | |
| F | ASN613 | |
| A | ASN279 | |
| F | ASN654 | |
| F | ASN1095 | |
| A | ASN328 | |
| A | ASN340 | |
| A | ASN613 | |
| A | ASN654 | |
| A | ASN1095 | |
| B | TYR165 | |
| B | ASN279 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN231 | |
| A | ASN706 | |
| B | ASN231 | |
| B | ASN706 | |
| F | ASN231 | |
| F | ASN706 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | THR320 | |
| B | THR320 | |
| F | THR320 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | SER322 | |
| B | SER322 | |
| F | SER322 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN600 | |
| B | ASN600 | |
| F | ASN600 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| A | THR673 | |
| A | THR675 | |
| B | THR673 | |
| B | THR675 | |
| F | THR673 | |
| F | THR675 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN1131 | |
| B | ASN1131 | |
| F | ASN1131 |
