7WE7
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0016020 | cellular_component | membrane |
| D | 0019031 | cellular_component | viral envelope |
| D | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| D | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| D | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| D | 0055036 | cellular_component | virion membrane |
| D | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| E | 0016020 | cellular_component | membrane |
| E | 0019031 | cellular_component | viral envelope |
| E | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| E | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| E | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| E | 0055036 | cellular_component | virion membrane |
| E | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| G | 0016020 | cellular_component | membrane |
| G | 0019031 | cellular_component | viral envelope |
| G | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| G | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| G | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| G | 0055036 | cellular_component | virion membrane |
| G | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3597 |
| Details | TOPO_DOM: Extracellular => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| D | GLN14-ILE1213 | |
| E | GLN14-ILE1213 | |
| G | GLN14-ILE1215 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| D | TRP1211-LEU1231 | |
| E | TRP1211-LEU1231 | |
| G | TRP1213-LEU1233 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 114 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255|HAMAP-Rule:MF_04099 |
| Chain | Residue | Details |
| D | CYS1232-THR1270 | |
| E | CYS1232-THR1270 | |
| G | CYS1234-THR1272 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| D | ARG682 | |
| E | ARG682 | |
| G | ARG684 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| D | ARG812 | |
| E | ARG812 | |
| G | ARG814 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 15 |
| Details | LIPID: S-palmitoyl cysteine; by host ZDHHC20 => ECO:0000269|PubMed:34599882 |
| Chain | Residue | Details |
| D | CYS1232 | |
| E | CYS1240 | |
| G | CYS1234 | |
| G | CYS1235 | |
| G | CYS1239 | |
| G | CYS1240 | |
| G | CYS1242 | |
| D | CYS1233 | |
| D | CYS1237 | |
| D | CYS1238 | |
| D | CYS1240 | |
| E | CYS1232 | |
| E | CYS1233 | |
| E | CYS1237 | |
| E | CYS1238 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 15 |
| Details | LIPID: S-palmitoyl cysteine; by host ZDHHC20; partial => ECO:0000269|PubMed:34599882 |
| Chain | Residue | Details |
| D | CYS1244 | |
| E | CYS1251 | |
| G | CYS1246 | |
| G | CYS1247 | |
| G | CYS1249 | |
| G | CYS1252 | |
| G | CYS1253 | |
| D | CYS1245 | |
| D | CYS1247 | |
| D | CYS1250 | |
| D | CYS1251 | |
| E | CYS1244 | |
| E | CYS1245 | |
| E | CYS1247 | |
| E | CYS1250 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| D | ASN17 | |
| D | ASN1155 | |
| D | ASN1170 | |
| E | ASN17 | |
| E | ASN1155 | |
| E | ASN1170 | |
| G | ASN17 | |
| G | ASN1157 | |
| G | ASN1172 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 15 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| D | ASN61 | |
| E | ASN1071 | |
| G | ASN61 | |
| G | THR124 | |
| G | ASN716 | |
| G | ASN800 | |
| G | ASN1073 | |
| D | THR122 | |
| D | ASN714 | |
| D | ASN798 | |
| D | ASN1071 | |
| E | ASN61 | |
| E | THR122 | |
| E | ASN714 | |
| E | ASN798 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| D | THR74 | |
| D | GLU149 | |
| D | ASN1191 | |
| E | THR74 | |
| E | GLU149 | |
| E | ASN1191 | |
| G | THR76 | |
| G | GLU151 | |
| G | ASN1193 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 21 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| D | TYR165 | |
| E | ASN328 | |
| E | ASN340 | |
| E | ASN613 | |
| E | ASN654 | |
| E | ASN1095 | |
| G | TYR167 | |
| G | ASN281 | |
| G | ASN330 | |
| G | ASN342 | |
| G | ASN615 | |
| D | ASN279 | |
| G | ASN656 | |
| G | ASN1097 | |
| D | ASN328 | |
| D | ASN340 | |
| D | ASN613 | |
| D | ASN654 | |
| D | ASN1095 | |
| E | TYR165 | |
| E | ASN279 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| D | ASN231 | |
| D | ASN706 | |
| E | ASN231 | |
| E | ASN706 | |
| G | ASN233 | |
| G | ASN708 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| D | THR320 | |
| E | THR320 | |
| G | THR322 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| D | SER322 | |
| E | SER322 | |
| G | SER324 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| D | ASN600 | |
| E | ASN600 | |
| G | ASN602 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| D | THR673 | |
| D | THR675 | |
| E | THR673 | |
| E | THR675 | |
| G | THR675 | |
| G | THR677 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| D | ASN1131 | |
| E | ASN1131 | |
| G | ASN1133 |
