Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7VXU

Matrix arm of deactive state CI from Q10 dataset

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005743	cellular_component	mitochondrial inner membrane
A	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0010181	molecular_function	FMN binding
A	0022904	biological_process	respiratory electron transport chain
A	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
A	0045271	cellular_component	respiratory chain complex I
A	0046872	molecular_function	metal ion binding
A	0051287	molecular_function	NAD binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	1902600	biological_process	proton transmembrane transport
B	0016020	cellular_component	membrane
B	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0048038	molecular_function	quinone binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0045271	cellular_component	respiratory chain complex I
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0022904	biological_process	respiratory electron transport chain
F	0045271	cellular_component	respiratory chain complex I
G	0000035	molecular_function	acyl binding
G	0000036	molecular_function	acyl carrier activity
G	0005198	molecular_function	structural molecule activity
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006629	biological_process	lipid metabolic process
G	0006631	biological_process	fatty acid metabolic process
G	0006633	biological_process	fatty acid biosynthetic process
G	0009249	biological_process	protein lipoylation
G	0022904	biological_process	respiratory electron transport chain
G	0031966	cellular_component	mitochondrial membrane
G	0044571	biological_process	[2Fe-2S] cluster assembly
G	0045271	cellular_component	respiratory chain complex I
G	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
G	0140978	molecular_function	mitochondrial large ribosomal subunit binding
G	1902775	biological_process	mitochondrial large ribosomal subunit assembly
H	0005743	cellular_component	mitochondrial inner membrane
H	0022904	biological_process	respiratory electron transport chain
H	0045271	cellular_component	respiratory chain complex I
I	0005743	cellular_component	mitochondrial inner membrane
I	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
I	0022904	biological_process	respiratory electron transport chain
I	0042773	biological_process	ATP synthesis coupled electron transport
I	0045271	cellular_component	respiratory chain complex I
J	0000166	molecular_function	nucleotide binding
J	0005759	cellular_component	mitochondrial matrix
J	0022904	biological_process	respiratory electron transport chain
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0022904	biological_process	respiratory electron transport chain
K	0045271	cellular_component	respiratory chain complex I
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0007420	biological_process	brain development
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0016020	cellular_component	membrane
L	0022900	biological_process	electron transport chain
L	0022904	biological_process	respiratory electron transport chain
L	0032981	biological_process	mitochondrial respiratory chain complex I assembly
L	0045271	cellular_component	respiratory chain complex I
L	0051591	biological_process	response to cAMP
L	0072593	biological_process	reactive oxygen species metabolic process
L	1902600	biological_process	proton transmembrane transport
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005758	cellular_component	mitochondrial intermembrane space
M	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009055	molecular_function	electron transfer activity
M	0016020	cellular_component	membrane
M	0016491	molecular_function	oxidoreductase activity
M	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
M	0022904	biological_process	respiratory electron transport chain
M	0032981	biological_process	mitochondrial respiratory chain complex I assembly
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0045271	cellular_component	respiratory chain complex I
M	0045333	biological_process	cellular respiration
M	0046872	molecular_function	metal ion binding
M	0051536	molecular_function	iron-sulfur cluster binding
M	0051537	molecular_function	2 iron, 2 sulfur cluster binding
M	0051539	molecular_function	4 iron, 4 sulfur cluster binding
M	1902600	biological_process	proton transmembrane transport
N	0005743	cellular_component	mitochondrial inner membrane
N	0016020	cellular_component	membrane
N	0022904	biological_process	respiratory electron transport chain
N	0045271	cellular_component	respiratory chain complex I
O	0003954	molecular_function	NADH dehydrogenase activity
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
O	0007399	biological_process	nervous system development
O	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
O	0016491	molecular_function	oxidoreductase activity
O	0045271	cellular_component	respiratory chain complex I
O	0046872	molecular_function	metal ion binding
O	0048738	biological_process	cardiac muscle tissue development
O	0051536	molecular_function	iron-sulfur cluster binding
O	0051537	molecular_function	2 iron, 2 sulfur cluster binding
O	1902600	biological_process	proton transmembrane transport
P	0003954	molecular_function	NADH dehydrogenase activity
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
P	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
P	0016020	cellular_component	membrane
P	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
P	0031966	cellular_component	mitochondrial membrane
P	0032981	biological_process	mitochondrial respiratory chain complex I assembly
P	0045271	cellular_component	respiratory chain complex I
P	0072593	biological_process	reactive oxygen species metabolic process
P	1902600	biological_process	proton transmembrane transport
Q	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
Q	0048038	molecular_function	quinone binding
Q	0051287	molecular_function	NAD binding
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
T	0022904	biological_process	respiratory electron transport chain
T	0045271	cellular_component	respiratory chain complex I
T	0046872	molecular_function	metal ion binding
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0016020	cellular_component	membrane
W	0022904	biological_process	respiratory electron transport chain
W	0045271	cellular_component	respiratory chain complex I

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
G	ASP107-MET122

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
G	ASP132-ILE144

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
B	CYS113-PRO124
B	CYS152-PRO163

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
Q	LEU116-LYS127

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL

Chain	Residue	Details
P	GLU167-LEU188

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
M	PRO61-CYS78

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
M	CYS128-GLN140

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
M	ARG175-PHE185

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
A	GLY200-SER215

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
A	GLU377-GLY388

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
O	ASP166-PRO184

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
C	GLY152-PRO168

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)