7VXK
SARS-CoV-2 spike protein in complex with ACE2, Beta variant, C2A state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0019031 | cellular_component | viral envelope |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| A | 0055036 | cellular_component | virion membrane |
| A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| B | 0016020 | cellular_component | membrane |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0055036 | cellular_component | virion membrane |
| B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| C | 0006508 | biological_process | proteolysis |
| C | 0008237 | molecular_function | metallopeptidase activity |
| C | 0008241 | molecular_function | peptidyl-dipeptidase activity |
| C | 0016020 | cellular_component | membrane |
| D | 0016020 | cellular_component | membrane |
| D | 0019031 | cellular_component | viral envelope |
| D | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| D | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| D | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| D | 0055036 | cellular_component | virion membrane |
| D | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAHHEMGHIQ |
| Chain | Residue | Details |
| C | THR371-GLN380 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01355, ECO:0000305|PubMed:14754895, ECO:0000305|PubMed:27217402 |
| Chain | Residue | Details |
| C | GLU375 | |
| D | ALA688 | |
| B | ALA688 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01355, ECO:0000305|PubMed:14754895 |
| Chain | Residue | Details |
| C | HIS505 | |
| D | ILE818 | |
| B | ILE818 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01355, ECO:0000269|PubMed:14754895, ECO:0000305|PubMed:19021774 |
| Chain | Residue | Details |
| C | ARG169 | |
| C | TRP477 | |
| C | LYS481 | |
| D | ASN17 | |
| D | SER1161 | |
| D | VAL1176 | |
| B | ASN17 | |
| B | SER1161 | |
| B | VAL1176 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:14754895 |
| Chain | Residue | Details |
| C | ARG273 | |
| D | THR1077 | |
| B | ASN61 | |
| B | ASN122 | |
| B | ILE720 | |
| B | GLN804 | |
| B | THR1077 | |
| C | HIS345 | |
| C | TYR515 | |
| A | GLN804 | |
| A | THR1077 | |
| D | ASN61 | |
| D | ASN122 | |
| D | ILE720 | |
| D | GLN804 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01355, ECO:0000269|PubMed:14754895 |
| Chain | Residue | Details |
| C | HIS374 | |
| C | HIS378 | |
| C | GLU402 | |
| D | ASN74 | |
| D | ASN149 | |
| D | LEU1197 | |
| B | ASN74 | |
| B | ASN149 | |
| B | LEU1197 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305|PubMed:14754895 |
| Chain | Residue | Details |
| C | ASN53 | |
| D | ASN334 | |
| D | ARG346 | |
| D | GLU619 | |
| D | TYR660 | |
| D | HIS1101 | |
| B | ASN165 | |
| B | ILE285 | |
| B | ASN334 | |
| B | ARG346 | |
| B | GLU619 | |
| C | ASN322 | |
| B | TYR660 | |
| B | HIS1101 | |
| A | ASN334 | |
| A | ARG346 | |
| A | GLU619 | |
| A | TYR660 | |
| A | HIS1101 | |
| D | ASN165 | |
| D | ILE285 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14754895, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:19901337 |
| Chain | Residue | Details |
| C | ASN90 | |
| A | ILE712 | |
| D | ASN234 | |
| D | ILE712 | |
| B | ASN234 | |
| B | ILE712 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14754895 |
| Chain | Residue | Details |
| C | ASN103 | |
| C | ASN432 | |
| B | ILE326 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14754895, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19901337 |
| Chain | Residue | Details |
| C | ASN546 | |
| D | ARG328 | |
| B | ARG328 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN606 | |
| D | ASN606 | |
| B | ASN606 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| A | ASN679 | |
| A | PRO681 | |
| D | ASN679 | |
| D | PRO681 | |
| B | ASN679 | |
| B | PRO681 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | VAL1137 | |
| D | VAL1137 | |
| B | VAL1137 |
