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7VUF

Crystal Structure of the core region of Thermus thermophilus MutS2.

Functional Information from GO Data
ChainGOidnamespacecontents
A0004519molecular_functionendonuclease activity
A0005524molecular_functionATP binding
A0006298biological_processmismatch repair
A0016887molecular_functionATP hydrolysis activity
A0030983molecular_functionmismatched DNA binding
A0045910biological_processnegative regulation of DNA recombination
A0140664molecular_functionATP-dependent DNA damage sensor activity
B0004519molecular_functionendonuclease activity
B0005524molecular_functionATP binding
B0006298biological_processmismatch repair
B0016887molecular_functionATP hydrolysis activity
B0030983molecular_functionmismatched DNA binding
B0045910biological_processnegative regulation of DNA recombination
B0140664molecular_functionATP-dependent DNA damage sensor activity
C0004519molecular_functionendonuclease activity
C0005524molecular_functionATP binding
C0006298biological_processmismatch repair
C0016887molecular_functionATP hydrolysis activity
C0030983molecular_functionmismatched DNA binding
C0045910biological_processnegative regulation of DNA recombination
C0140664molecular_functionATP-dependent DNA damage sensor activity
D0004519molecular_functionendonuclease activity
D0005524molecular_functionATP binding
D0006298biological_processmismatch repair
D0016887molecular_functionATP hydrolysis activity
D0030983molecular_functionmismatched DNA binding
D0045910biological_processnegative regulation of DNA recombination
D0140664molecular_functionATP-dependent DNA damage sensor activity
Functional Information from PROSITE/UniProt
site_idPS00486
Number of Residues17
DetailsDNA_MISMATCH_REPAIR_2 DNA mismatch repair proteins mutS family signature. SLvLiDELGSGTdpeeG
ChainResidueDetails
BSER389-GLY405

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues28
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00092","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

238895

PDB entries from 2025-07-16

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