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7VGS

SARS-CoV-2 M protein dimer (short form) in complex with YN7717_9 Fab

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
A0005886cellular_componentplasma membrane
A0016020cellular_componentmembrane
A0019031cellular_componentviral envelope
A0019049biological_processvirus-mediated perturbation of host defense response
A0030430cellular_componenthost cell cytoplasm
A0033644cellular_componenthost cell membrane
A0039545biological_processsymbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
A0039660molecular_functionstructural constituent of virion
A0039709biological_processcytoplasmic capsid assembly
A0042802molecular_functionidentical protein binding
A0044177cellular_componenthost cell Golgi apparatus
A0044178cellular_componenthost cell Golgi membrane
A0055036cellular_componentvirion membrane
A0140311molecular_functionprotein sequestering activity
B0005515molecular_functionprotein binding
B0005793cellular_componentendoplasmic reticulum-Golgi intermediate compartment
B0005886cellular_componentplasma membrane
B0016020cellular_componentmembrane
B0019031cellular_componentviral envelope
B0019049biological_processvirus-mediated perturbation of host defense response
B0030430cellular_componenthost cell cytoplasm
B0033644cellular_componenthost cell membrane
B0039545biological_processsymbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
B0039660molecular_functionstructural constituent of virion
B0039709biological_processcytoplasmic capsid assembly
B0042802molecular_functionidentical protein binding
B0044177cellular_componenthost cell Golgi apparatus
B0044178cellular_componenthost cell Golgi membrane
B0055036cellular_componentvirion membrane
B0140311molecular_functionprotein sequestering activity
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
CTYR196-HIS202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues36
DetailsTOPO_DOM: Virion surface => ECO:0000269|PubMed:36264056
ChainResidueDetails
AALA2-LEU16
ATYR71-TRP75
BALA2-LEU16
BTYR71-TRP75

site_idSWS_FT_FI2
Number of Residues146
DetailsTRANSMEM: Helical => ECO:0000269|PubMed:36264056
ChainResidueDetails
ALEU17-GLN36
APHE45-VAL70
AILE76-ARG105
BLEU17-GLN36
BPHE45-VAL70
BILE76-ARG105

site_idSWS_FT_FI3
Number of Residues246
DetailsTOPO_DOM: Intravirion => ECO:0000269|PubMed:36264056
ChainResidueDetails
APHE37-ARG44
ATHR106-GLN222
BPHE37-ARG44
BTHR106-GLN222

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:35931673, ECO:0000269|PubMed:36264056, ECO:0000269|PubMed:38666819
ChainResidueDetails
AASN5
BASN5

225946

PDB entries from 2024-10-09

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