7VGG
Cryo-EM structure of Ultraviolet-B activated UVR8 in complex with COP1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000152 | cellular_component | nuclear ubiquitin ligase complex |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009585 | biological_process | red, far-red light phototransduction |
| A | 0009640 | biological_process | photomorphogenesis |
| A | 0009641 | biological_process | shade avoidance |
| A | 0009647 | biological_process | skotomorphogenesis |
| A | 0009649 | biological_process | entrainment of circadian clock |
| A | 0009963 | biological_process | positive regulation of flavonoid biosynthetic process |
| A | 0010017 | biological_process | red or far-red light signaling pathway |
| A | 0010119 | biological_process | regulation of stomatal movement |
| A | 0010224 | biological_process | response to UV-B |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016604 | cellular_component | nuclear body |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0043161 | biological_process | proteasome-mediated ubiquitin-dependent protein catabolic process |
| A | 0046283 | biological_process | anthocyanin-containing compound metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048573 | biological_process | photoperiodism, flowering |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
| A | 0080008 | cellular_component | Cul4-RING E3 ubiquitin ligase complex |
| B | 0000785 | cellular_component | chromatin |
| B | 0003682 | molecular_function | chromatin binding |
| B | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0009411 | biological_process | response to UV |
| B | 0009536 | cellular_component | plastid |
| B | 0009649 | biological_process | entrainment of circadian clock |
| B | 0009881 | molecular_function | photoreceptor activity |
| B | 0010224 | biological_process | response to UV-B |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CgHsFCymCI |
| Chain | Residue | Details |
| A | CYS67-ILE76 |
| site_id | PS00626 |
| Number of Residues | 11 |
| Details | RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. ISAGaSHSVAL |
| Chain | Residue | Details |
| B | ILE20-LEU30 | |
| B | VAL177-VAL187 | |
| B | VAL229-VAL239 | |
| B | ILE281-LEU291 | |
| B | VAL333-VAL343 |
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAstDsTLRLWDV |
| Chain | Residue | Details |
| A | LEU563-VAL577 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 38 |
| Details | Repeat: {"description":"WD 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"WD 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Region: {"description":"Binding of human TRIB1 COP1-binding-motif","evidences":[{"source":"PubMed","id":"27041596","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Site: {"description":"Human TRIB1 COP1-binding motif","evidences":[{"source":"PubMed","id":"27041596","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 52 |
| Details | Repeat: {"description":"RCC1 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 51 |
| Details | Repeat: {"description":"RCC1 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"RCC1 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 51 |
| Details | Repeat: {"description":"RCC1 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"RCC1 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 51 |
| Details | Repeat: {"description":"RCC1 7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
