Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7VBL

Membrane arm of active state CI from DQ-NADH dataset

Functional Information from GO Data

Chain	GOid	namespace	contents
b	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
b	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c	0005739	cellular_component	mitochondrion
c	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
c	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
f	0005739	cellular_component	mitochondrion
f	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
g	0005737	cellular_component	cytoplasm
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
g	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
g	0032981	biological_process	mitochondrial respiratory chain complex I assembly
g	0070469	cellular_component	respirasome
h	0005739	cellular_component	mitochondrion
h	0005743	cellular_component	mitochondrial inner membrane
h	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
h	0005758	cellular_component	mitochondrial intermembrane space
h	0032981	biological_process	mitochondrial respiratory chain complex I assembly
h	0070469	cellular_component	respirasome
i	0005739	cellular_component	mitochondrion
i	0005743	cellular_component	mitochondrial inner membrane
i	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
i	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
i	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
i	0032981	biological_process	mitochondrial respiratory chain complex I assembly
i	0070469	cellular_component	respirasome
i	0072593	biological_process	reactive oxygen species metabolic process
i	1902600	biological_process	proton transmembrane transport
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
j	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
j	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
j	0070469	cellular_component	respirasome
j	1902600	biological_process	proton transmembrane transport
k	0005739	cellular_component	mitochondrion
k	0005743	cellular_component	mitochondrial inner membrane
k	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
k	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
k	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
k	0042773	biological_process	ATP synthesis coupled electron transport
k	0045271	cellular_component	respiratory chain complex I
k	0070469	cellular_component	respirasome
k	1902600	biological_process	proton transmembrane transport
l	0003954	molecular_function	NADH dehydrogenase activity
l	0005739	cellular_component	mitochondrion
l	0005743	cellular_component	mitochondrial inner membrane
l	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
l	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
l	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
l	0015990	biological_process	electron transport coupled proton transport
l	0032981	biological_process	mitochondrial respiratory chain complex I assembly
l	0042773	biological_process	ATP synthesis coupled electron transport
l	0070469	cellular_component	respirasome
m	0005739	cellular_component	mitochondrion
m	0005743	cellular_component	mitochondrial inner membrane
m	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
m	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
m	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
m	0032981	biological_process	mitochondrial respiratory chain complex I assembly
m	0070469	cellular_component	respirasome
m	1902600	biological_process	proton transmembrane transport
n	0005739	cellular_component	mitochondrion
n	0005743	cellular_component	mitochondrial inner membrane
n	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
n	0016607	cellular_component	nuclear speck
n	0032981	biological_process	mitochondrial respiratory chain complex I assembly
o	0005654	cellular_component	nucleoplasm
o	0005739	cellular_component	mitochondrion
o	0005743	cellular_component	mitochondrial inner membrane
o	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
o	0006979	biological_process	response to oxidative stress
o	0016020	cellular_component	membrane
o	0032981	biological_process	mitochondrial respiratory chain complex I assembly
p	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
r	0003954	molecular_function	NADH dehydrogenase activity
r	0005739	cellular_component	mitochondrion
r	0005743	cellular_component	mitochondrial inner membrane
r	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
r	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
r	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
r	0009060	biological_process	aerobic respiration
r	0015990	biological_process	electron transport coupled proton transport
r	0032981	biological_process	mitochondrial respiratory chain complex I assembly
r	0042773	biological_process	ATP synthesis coupled electron transport
r	0048039	molecular_function	ubiquinone binding
r	0070469	cellular_component	respirasome
s	0003954	molecular_function	NADH dehydrogenase activity
s	0005739	cellular_component	mitochondrion
s	0005743	cellular_component	mitochondrial inner membrane
s	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
s	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
s	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
s	0009060	biological_process	aerobic respiration
s	0016020	cellular_component	membrane
s	0032981	biological_process	mitochondrial respiratory chain complex I assembly
s	0070469	cellular_component	respirasome
s	1902600	biological_process	proton transmembrane transport
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
S	0031966	cellular_component	mitochondrial membrane
S	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S	0070469	cellular_component	respirasome
u	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
U	0005743	cellular_component	mitochondrial inner membrane
U	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
v	0005739	cellular_component	mitochondrion
v	0005743	cellular_component	mitochondrial inner membrane
v	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
v	0005758	cellular_component	mitochondrial intermembrane space
v	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
v	0016020	cellular_component	membrane
v	0032981	biological_process	mitochondrial respiratory chain complex I assembly
v	1902600	biological_process	proton transmembrane transport
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
V	0032981	biological_process	mitochondrial respiratory chain complex I assembly
w	0005737	cellular_component	cytoplasm
w	0005739	cellular_component	mitochondrion
w	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
w	0005759	cellular_component	mitochondrial matrix
w	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
w	0070469	cellular_component	respirasome
X	0006633	biological_process	fatty acid biosynthetic process
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005747	cellular_component	obsolete mitochondrial respiratory chain complex I
Z	0005739	cellular_component	mitochondrion
Z	0022900	biological_process	electron transport chain

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
X	ASP107-MET122

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
X	ASP132-ILE144

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDALKLFtKE

Chain	Residue	Details
s	GLY44-GLU59

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
s	PRO197-GLY210

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	322
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
l	MET1-MET21
l	ILE301-GLN321
l	LEU324-GLY344
l	MET366-LEU386
l	TRP407-PHE429
l	LEU457-VAL477
l	MET482-LEU502
l	GLY582-PHE602
l	ALA43-ILE63
l	VAL87-TYR107
l	PRO112-VAL132
l	LEU137-TRP157
l	ALA171-THR191
l	LEU213-LEU233
l	THR241-ILE261
l	VAL273-ILE293

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)