7V7U
Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 2
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016020 | cellular_component | membrane |
A | 0019031 | cellular_component | viral envelope |
A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
A | 0055036 | cellular_component | virion membrane |
A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
B | 0016020 | cellular_component | membrane |
B | 0019031 | cellular_component | viral envelope |
B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
B | 0055036 | cellular_component | virion membrane |
B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
C | 0016020 | cellular_component | membrane |
C | 0019031 | cellular_component | viral envelope |
C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
C | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
C | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
C | 0055036 | cellular_component | virion membrane |
C | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
Chain | Residue | Details |
A | VAL685 | |
B | VAL685 | |
C | VAL685 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
Chain | Residue | Details |
A | PHE815 | |
B | PHE815 | |
C | PHE815 |
site_id | SWS_FT_FI3 |
Number of Residues | 9 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN17 | |
A | THR1158 | |
A | SER1173 | |
B | ASN17 | |
B | THR1158 | |
B | SER1173 | |
C | ASN17 | |
C | THR1158 | |
C | SER1173 |
site_id | SWS_FT_FI4 |
Number of Residues | 15 |
Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN61 | |
B | THR1074 | |
C | ASN61 | |
C | ASN122 | |
C | THR717 | |
C | SER801 | |
C | THR1074 | |
A | ASN122 | |
A | THR717 | |
A | SER801 | |
A | THR1074 | |
B | ASN61 | |
B | ASN122 | |
B | THR717 | |
B | SER801 |
site_id | SWS_FT_FI5 |
Number of Residues | 9 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN74 | |
A | ASN149 | |
A | SER1194 | |
B | ASN74 | |
B | ASN149 | |
B | SER1194 | |
C | ASN74 | |
C | ASN149 | |
C | SER1194 |
site_id | SWS_FT_FI6 |
Number of Residues | 21 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | THR165 | |
B | THR331 | |
B | THR343 | |
B | THR616 | |
B | SER657 | |
B | THR1098 | |
C | THR165 | |
C | THR282 | |
C | THR331 | |
C | THR343 | |
C | THR616 | |
A | THR282 | |
C | SER657 | |
C | THR1098 | |
A | THR331 | |
A | THR343 | |
A | THR616 | |
A | SER657 | |
A | THR1098 | |
B | THR165 | |
B | THR282 |
site_id | SWS_FT_FI7 |
Number of Residues | 6 |
Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | THR234 | |
A | SER709 | |
B | THR234 | |
B | SER709 | |
C | THR234 | |
C | SER709 |
site_id | SWS_FT_FI8 |
Number of Residues | 3 |
Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
Chain | Residue | Details |
A | SER323 | |
B | SER323 | |
C | SER323 |
site_id | SWS_FT_FI9 |
Number of Residues | 3 |
Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
Chain | Residue | Details |
A | VAL325 | |
B | VAL325 | |
C | VAL325 |
site_id | SWS_FT_FI10 |
Number of Residues | 3 |
Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | SER603 | |
B | SER603 | |
C | SER603 |
site_id | SWS_FT_FI11 |
Number of Residues | 6 |
Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
Chain | Residue | Details |
A | THR676 | |
A | SER678 | |
B | THR676 | |
B | SER678 | |
C | THR676 | |
C | SER678 |
site_id | SWS_FT_FI12 |
Number of Residues | 3 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | THR1134 | |
B | THR1134 | |
C | THR1134 |