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7V2W

protomer structure from the dimer of yeast THO complex

Functional Information from GO Data
ChainGOidnamespacecontents
F0000445cellular_componentTHO complex part of transcription export complex
F0000446cellular_componentnucleoplasmic THO complex
F0000781cellular_componentchromosome, telomeric region
F0003676molecular_functionnucleic acid binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0006283biological_processtranscription-coupled nucleotide-excision repair
F0006310biological_processDNA recombination
F0006351biological_processDNA-templated transcription
F0006368biological_processtranscription elongation by RNA polymerase II
F0006406biological_processmRNA export from nucleus
F0016593cellular_componentCdc73/Paf1 complex
F0031124biological_processmRNA 3'-end processing
F0045943biological_processpositive regulation of transcription by RNA polymerase I
F0060090molecular_functionmolecular adaptor activity
F2001209biological_processpositive regulation of transcription elongation by RNA polymerase I
G0000347cellular_componentTHO complex
G0000445cellular_componentTHO complex part of transcription export complex
G0000446cellular_componentnucleoplasmic THO complex
G0000781cellular_componentchromosome, telomeric region
G0003676molecular_functionnucleic acid binding
G0003729molecular_functionmRNA binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0006283biological_processtranscription-coupled nucleotide-excision repair
G0006310biological_processDNA recombination
G0006351biological_processDNA-templated transcription
G0006368biological_processtranscription elongation by RNA polymerase II
G0006397biological_processmRNA processing
G0006406biological_processmRNA export from nucleus
G0031124biological_processmRNA 3'-end processing
G0034063biological_processstress granule assembly
G0045943biological_processpositive regulation of transcription by RNA polymerase I
G0097185biological_processcellular response to azide
G2001209biological_processpositive regulation of transcription elongation by RNA polymerase I
H0000346cellular_componenttranscription export complex
H0000445cellular_componentTHO complex part of transcription export complex
H0003729molecular_functionmRNA binding
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0006351biological_processDNA-templated transcription
H0006368biological_processtranscription elongation by RNA polymerase II
H0006406biological_processmRNA export from nucleus
I0000445cellular_componentTHO complex part of transcription export complex
I0000446cellular_componentnucleoplasmic THO complex
I0000781cellular_componentchromosome, telomeric region
I0003676molecular_functionnucleic acid binding
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0006310biological_processDNA recombination
I0006351biological_processDNA-templated transcription
I0006368biological_processtranscription elongation by RNA polymerase II
I0006397biological_processmRNA processing
I0006406biological_processmRNA export from nucleus
I0060090molecular_functionmolecular adaptor activity
J0000445cellular_componentTHO complex part of transcription export complex
J0000446cellular_componentnucleoplasmic THO complex
J0003676molecular_functionnucleic acid binding
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0006310biological_processDNA recombination
J0006351biological_processDNA-templated transcription
J0006368biological_processtranscription elongation by RNA polymerase II
J0006406biological_processmRNA export from nucleus
J0034063biological_processstress granule assembly
J0097185biological_processcellular response to azide
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues39
DetailsRepeat: {"description":"WD 1"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues39
DetailsRepeat: {"description":"WD 2"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues39
DetailsRepeat: {"description":"WD 3"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues39
DetailsRepeat: {"description":"WD 4"}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues39
DetailsRepeat: {"description":"WD 5"}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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