7UY8

Tetrahymena Polymerase alpha-Primase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003682	molecular_function	chromatin binding
A	0003688	molecular_function	DNA replication origin binding
A	0003697	molecular_function	single-stranded DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005634	cellular_component	nucleus
A	0005658	cellular_component	alpha DNA polymerase:primase complex
A	0006260	biological_process	DNA replication
A	0006272	biological_process	leading strand elongation
A	0006273	biological_process	lagging strand elongation
A	0008270	molecular_function	zinc ion binding
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0046872	molecular_function	metal ion binding
A	0071897	biological_process	DNA biosynthetic process
A	1902975	biological_process	mitotic DNA replication initiation
B	0003677	molecular_function	DNA binding
B	0005634	cellular_component	nucleus
B	0005658	cellular_component	alpha DNA polymerase:primase complex
B	0006260	biological_process	DNA replication
B	0006270	biological_process	DNA replication initiation
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0005658	cellular_component	alpha DNA polymerase:primase complex
C	0006260	biological_process	DNA replication
C	0006261	biological_process	DNA-templated DNA replication
C	0006269	biological_process	DNA replication, synthesis of primer
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0046872	molecular_function	metal ion binding
D	0003677	molecular_function	DNA binding
D	0005658	cellular_component	alpha DNA polymerase:primase complex
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication
D	0006269	biological_process	DNA replication, synthesis of primer
D	0006270	biological_process	DNA replication initiation
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PROSITE/UniProt

site_id	PS00116
Number of Residues	9
Details	DNA_POLYMERASE_B DNA polymerase family B signature. YGDTDSLMI

Chain	Residue	Details
A	TYR961-ILE969

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