7UY7

Tetrahymena CST with Polymerase alpha-Primase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000781	cellular_component	chromosome, telomeric region
A	0005697	cellular_component	telomerase holoenzyme complex
B	0000781	cellular_component	chromosome, telomeric region
B	0005515	molecular_function	protein binding
B	0005697	cellular_component	telomerase holoenzyme complex
B	0007004	biological_process	telomere maintenance via telomerase
B	0046872	molecular_function	metal ion binding
C	0000781	cellular_component	chromosome, telomeric region
C	0005515	molecular_function	protein binding
C	0005697	cellular_component	telomerase holoenzyme complex
C	0007004	biological_process	telomere maintenance via telomerase
D	0000781	cellular_component	chromosome, telomeric region
D	0005697	cellular_component	telomerase holoenzyme complex
D	0007004	biological_process	telomere maintenance via telomerase
E	0000166	molecular_function	nucleotide binding
E	0003676	molecular_function	nucleic acid binding
E	0003677	molecular_function	DNA binding
E	0003682	molecular_function	chromatin binding
E	0003688	molecular_function	DNA replication origin binding
E	0003697	molecular_function	single-stranded DNA binding
E	0003887	molecular_function	DNA-directed DNA polymerase activity
E	0005634	cellular_component	nucleus
E	0005658	cellular_component	alpha DNA polymerase:primase complex
E	0006260	biological_process	DNA replication
E	0006272	biological_process	leading strand elongation
E	0006273	biological_process	lagging strand elongation
E	0008270	molecular_function	zinc ion binding
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0034061	molecular_function	DNA polymerase activity
E	0046872	molecular_function	metal ion binding
E	0071897	biological_process	DNA biosynthetic process
E	1902975	biological_process	mitotic DNA replication initiation

Functional Information from PROSITE/UniProt

site_id	PS00116
Number of Residues	9
Details	DNA_POLYMERASE_B DNA polymerase family B signature. YGDTDSLMI

Chain	Residue	Details
E	TYR961-ILE969

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26551074","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DOK","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Minor DNA-binding site","evidences":[{"source":"PubMed","id":"21549126","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---