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7UTL

ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM FREE STATE

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
a0001725cellular_componentstress fiber
a0003065biological_processpositive regulation of heart rate by epinephrine
a0003779molecular_functionactin binding
a0005200molecular_functionstructural constituent of cytoskeleton
a0005515molecular_functionprotein binding
a0005737cellular_componentcytoplasm
a0005829cellular_componentcytosol
a0005856cellular_componentcytoskeleton
a0005862cellular_componentmuscle thin filament tropomyosin
a0005884cellular_componentactin filament
a0006937biological_processregulation of muscle contraction
a0007010biological_processcytoskeleton organization
a0007015biological_processactin filament organization
a0008016biological_processregulation of heart contraction
a0008092molecular_functioncytoskeletal protein binding
a0008307molecular_functionstructural constituent of muscle
a0008360biological_processregulation of cell shape
a0015629cellular_componentactin cytoskeleton
a0030017cellular_componentsarcomere
a0030049biological_processmuscle filament sliding
a0030336biological_processnegative regulation of cell migration
a0031529biological_processruffle organization
a0032059cellular_componentbleb
a0032587cellular_componentruffle membrane
a0032781biological_processpositive regulation of ATP-dependent activity
a0034614biological_processcellular response to reactive oxygen species
a0042060biological_processwound healing
a0042802molecular_functionidentical protein binding
a0042803molecular_functionprotein homodimerization activity
a0045214biological_processsarcomere organization
a0045785biological_processpositive regulation of cell adhesion
a0046982molecular_functionprotein heterodimerization activity
a0051015molecular_functionactin filament binding
a0051496biological_processpositive regulation of stress fiber assembly
a0055010biological_processventricular cardiac muscle tissue morphogenesis
a0060048biological_processcardiac muscle contraction
a1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
a1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
A0000287molecular_functionmagnesium ion binding
A0001725cellular_componentstress fiber
A0003785molecular_functionactin monomer binding
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005523molecular_functiontropomyosin binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005856cellular_componentcytoskeleton
A0005865cellular_componentstriated muscle thin filament
A0005884cellular_componentactin filament
A0010628biological_processpositive regulation of gene expression
A0016787molecular_functionhydrolase activity
A0019904molecular_functionprotein domain specific binding
A0030027cellular_componentlamellipodium
A0030041biological_processactin filament polymerization
A0030175cellular_componentfilopodium
A0030240biological_processskeletal muscle thin filament assembly
A0031013molecular_functiontroponin I binding
A0031432molecular_functiontitin binding
A0031941cellular_componentfilamentous actin
A0032036molecular_functionmyosin heavy chain binding
A0032432cellular_componentactin filament bundle
A0042802molecular_functionidentical protein binding
A0044297cellular_componentcell body
A0048306molecular_functioncalcium-dependent protein binding
A0048741biological_processskeletal muscle fiber development
A0051017biological_processactin filament bundle assembly
A0090131biological_processmesenchyme migration
A0098723cellular_componentskeletal muscle myofibril
A0140660molecular_functioncytoskeletal motor activator activity
b0001725cellular_componentstress fiber
b0003065biological_processpositive regulation of heart rate by epinephrine
b0003779molecular_functionactin binding
b0005200molecular_functionstructural constituent of cytoskeleton
b0005515molecular_functionprotein binding
b0005737cellular_componentcytoplasm
b0005829cellular_componentcytosol
b0005856cellular_componentcytoskeleton
b0005862cellular_componentmuscle thin filament tropomyosin
b0005884cellular_componentactin filament
b0006937biological_processregulation of muscle contraction
b0007010biological_processcytoskeleton organization
b0007015biological_processactin filament organization
b0008016biological_processregulation of heart contraction
b0008092molecular_functioncytoskeletal protein binding
b0008307molecular_functionstructural constituent of muscle
b0008360biological_processregulation of cell shape
b0015629cellular_componentactin cytoskeleton
b0030017cellular_componentsarcomere
b0030049biological_processmuscle filament sliding
b0030336biological_processnegative regulation of cell migration
b0031529biological_processruffle organization
b0032059cellular_componentbleb
b0032587cellular_componentruffle membrane
b0032781biological_processpositive regulation of ATP-dependent activity
b0034614biological_processcellular response to reactive oxygen species
b0042060biological_processwound healing
b0042802molecular_functionidentical protein binding
b0042803molecular_functionprotein homodimerization activity
b0045214biological_processsarcomere organization
b0045785biological_processpositive regulation of cell adhesion
b0046982molecular_functionprotein heterodimerization activity
b0051015molecular_functionactin filament binding
b0051496biological_processpositive regulation of stress fiber assembly
b0055010biological_processventricular cardiac muscle tissue morphogenesis
b0060048biological_processcardiac muscle contraction
b1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
b1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
B0000287molecular_functionmagnesium ion binding
B0001725cellular_componentstress fiber
B0003785molecular_functionactin monomer binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005523molecular_functiontropomyosin binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0005865cellular_componentstriated muscle thin filament
B0005884cellular_componentactin filament
B0010628biological_processpositive regulation of gene expression
B0016787molecular_functionhydrolase activity
B0019904molecular_functionprotein domain specific binding
B0030027cellular_componentlamellipodium
B0030041biological_processactin filament polymerization
B0030175cellular_componentfilopodium
B0030240biological_processskeletal muscle thin filament assembly
B0031013molecular_functiontroponin I binding
B0031432molecular_functiontitin binding
B0031941cellular_componentfilamentous actin
B0032036molecular_functionmyosin heavy chain binding
B0032432cellular_componentactin filament bundle
B0042802molecular_functionidentical protein binding
B0044297cellular_componentcell body
B0048306molecular_functioncalcium-dependent protein binding
B0048741biological_processskeletal muscle fiber development
B0051017biological_processactin filament bundle assembly
B0090131biological_processmesenchyme migration
B0098723cellular_componentskeletal muscle myofibril
B0140660molecular_functioncytoskeletal motor activator activity
c0001570biological_processvasculogenesis
c0001980biological_processregulation of systemic arterial blood pressure by ischemic conditions
c0003009biological_processskeletal muscle contraction
c0003779molecular_functionactin binding
c0005515molecular_functionprotein binding
c0005737cellular_componentcytoplasm
c0005829cellular_componentcytosol
c0005861cellular_componenttroponin complex
c0006874biological_processintracellular calcium ion homeostasis
c0006937biological_processregulation of muscle contraction
c0006940biological_processregulation of smooth muscle contraction
c0006941biological_processstriated muscle contraction
c0007507biological_processheart development
c0010882biological_processregulation of cardiac muscle contraction by calcium ion signaling
c0019855molecular_functioncalcium channel inhibitor activity
c0019901molecular_functionprotein kinase binding
c0019904molecular_functionprotein domain specific binding
c0030016cellular_componentmyofibril
c0030017cellular_componentsarcomere
c0030172molecular_functiontroponin C binding
c0031014molecular_functiontroponin T binding
c0032780biological_processnegative regulation of ATP-dependent activity
c0043292cellular_componentcontractile muscle fiber
c0048306molecular_functioncalcium-dependent protein binding
c0051015molecular_functionactin filament binding
c0055010biological_processventricular cardiac muscle tissue morphogenesis
c0060047biological_processheart contraction
c0060048biological_processcardiac muscle contraction
c0097512cellular_componentcardiac myofibril
c1990584cellular_componentcardiac Troponin complex
C0000287molecular_functionmagnesium ion binding
C0001725cellular_componentstress fiber
C0003785molecular_functionactin monomer binding
C0005509molecular_functioncalcium ion binding
C0005515molecular_functionprotein binding
C0005523molecular_functiontropomyosin binding
C0005524molecular_functionATP binding
C0005737cellular_componentcytoplasm
C0005856cellular_componentcytoskeleton
C0005865cellular_componentstriated muscle thin filament
C0005884cellular_componentactin filament
C0010628biological_processpositive regulation of gene expression
C0016787molecular_functionhydrolase activity
C0019904molecular_functionprotein domain specific binding
C0030027cellular_componentlamellipodium
C0030041biological_processactin filament polymerization
C0030175cellular_componentfilopodium
C0030240biological_processskeletal muscle thin filament assembly
C0031013molecular_functiontroponin I binding
C0031432molecular_functiontitin binding
C0031941cellular_componentfilamentous actin
C0032036molecular_functionmyosin heavy chain binding
C0032432cellular_componentactin filament bundle
C0042802molecular_functionidentical protein binding
C0044297cellular_componentcell body
C0048306molecular_functioncalcium-dependent protein binding
C0048741biological_processskeletal muscle fiber development
C0051017biological_processactin filament bundle assembly
C0090131biological_processmesenchyme migration
C0098723cellular_componentskeletal muscle myofibril
C0140660molecular_functioncytoskeletal motor activator activity
d0002086biological_processdiaphragm contraction
d0003009biological_processskeletal muscle contraction
d0005509molecular_functioncalcium ion binding
d0005515molecular_functionprotein binding
d0005829cellular_componentcytosol
d0005861cellular_componenttroponin complex
d0006937biological_processregulation of muscle contraction
d0010038biological_processresponse to metal ion
d0014883biological_processtransition between fast and slow fiber
d0031013molecular_functiontroponin I binding
d0031014molecular_functiontroponin T binding
d0032972biological_processregulation of muscle filament sliding speed
d0042803molecular_functionprotein homodimerization activity
d0043292cellular_componentcontractile muscle fiber
d0043462biological_processregulation of ATP-dependent activity
d0046872molecular_functionmetal ion binding
d0048306molecular_functioncalcium-dependent protein binding
d0051015molecular_functionactin filament binding
d0055010biological_processventricular cardiac muscle tissue morphogenesis
d0060048biological_processcardiac muscle contraction
d1990584cellular_componentcardiac Troponin complex
D0000287molecular_functionmagnesium ion binding
D0001725cellular_componentstress fiber
D0003785molecular_functionactin monomer binding
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005523molecular_functiontropomyosin binding
D0005524molecular_functionATP binding
D0005737cellular_componentcytoplasm
D0005856cellular_componentcytoskeleton
D0005865cellular_componentstriated muscle thin filament
D0005884cellular_componentactin filament
D0010628biological_processpositive regulation of gene expression
D0016787molecular_functionhydrolase activity
D0019904molecular_functionprotein domain specific binding
D0030027cellular_componentlamellipodium
D0030041biological_processactin filament polymerization
D0030175cellular_componentfilopodium
D0030240biological_processskeletal muscle thin filament assembly
D0031013molecular_functiontroponin I binding
D0031432molecular_functiontitin binding
D0031941cellular_componentfilamentous actin
D0032036molecular_functionmyosin heavy chain binding
D0032432cellular_componentactin filament bundle
D0042802molecular_functionidentical protein binding
D0044297cellular_componentcell body
D0048306molecular_functioncalcium-dependent protein binding
D0048741biological_processskeletal muscle fiber development
D0051017biological_processactin filament bundle assembly
D0090131biological_processmesenchyme migration
D0098723cellular_componentskeletal muscle myofibril
D0140660molecular_functioncytoskeletal motor activator activity
e0003779molecular_functionactin binding
e0005515molecular_functionprotein binding
e0005523molecular_functiontropomyosin binding
e0005829cellular_componentcytosol
e0005861cellular_componenttroponin complex
e0005865cellular_componentstriated muscle thin filament
e0006937biological_processregulation of muscle contraction
e0008016biological_processregulation of heart contraction
e0030017cellular_componentsarcomere
e0030049biological_processmuscle filament sliding
e0030172molecular_functiontroponin C binding
e0031013molecular_functiontroponin I binding
e0032780biological_processnegative regulation of ATP-dependent activity
e0032781biological_processpositive regulation of ATP-dependent activity
e0045214biological_processsarcomere organization
e0051592biological_processresponse to calcium ion
e0055010biological_processventricular cardiac muscle tissue morphogenesis
e0060048biological_processcardiac muscle contraction
e0097512cellular_componentcardiac myofibril
e1990584cellular_componentcardiac Troponin complex
E0000287molecular_functionmagnesium ion binding
E0001725cellular_componentstress fiber
E0003785molecular_functionactin monomer binding
E0005509molecular_functioncalcium ion binding
E0005515molecular_functionprotein binding
E0005523molecular_functiontropomyosin binding
E0005524molecular_functionATP binding
E0005737cellular_componentcytoplasm
E0005856cellular_componentcytoskeleton
E0005865cellular_componentstriated muscle thin filament
E0005884cellular_componentactin filament
E0010628biological_processpositive regulation of gene expression
E0016787molecular_functionhydrolase activity
E0019904molecular_functionprotein domain specific binding
E0030027cellular_componentlamellipodium
E0030041biological_processactin filament polymerization
E0030175cellular_componentfilopodium
E0030240biological_processskeletal muscle thin filament assembly
E0031013molecular_functiontroponin I binding
E0031432molecular_functiontitin binding
E0031941cellular_componentfilamentous actin
E0032036molecular_functionmyosin heavy chain binding
E0032432cellular_componentactin filament bundle
E0042802molecular_functionidentical protein binding
E0044297cellular_componentcell body
E0048306molecular_functioncalcium-dependent protein binding
E0048741biological_processskeletal muscle fiber development
E0051017biological_processactin filament bundle assembly
E0090131biological_processmesenchyme migration
E0098723cellular_componentskeletal muscle myofibril
E0140660molecular_functioncytoskeletal motor activator activity
f0003779molecular_functionactin binding
f0005515molecular_functionprotein binding
f0005523molecular_functiontropomyosin binding
f0005829cellular_componentcytosol
f0005861cellular_componenttroponin complex
f0005865cellular_componentstriated muscle thin filament
f0006937biological_processregulation of muscle contraction
f0008016biological_processregulation of heart contraction
f0030017cellular_componentsarcomere
f0030049biological_processmuscle filament sliding
f0030172molecular_functiontroponin C binding
f0031013molecular_functiontroponin I binding
f0032780biological_processnegative regulation of ATP-dependent activity
f0032781biological_processpositive regulation of ATP-dependent activity
f0045214biological_processsarcomere organization
f0051592biological_processresponse to calcium ion
f0055010biological_processventricular cardiac muscle tissue morphogenesis
f0060048biological_processcardiac muscle contraction
f0097512cellular_componentcardiac myofibril
f1990584cellular_componentcardiac Troponin complex
F0000287molecular_functionmagnesium ion binding
F0001725cellular_componentstress fiber
F0003785molecular_functionactin monomer binding
F0005509molecular_functioncalcium ion binding
F0005515molecular_functionprotein binding
F0005523molecular_functiontropomyosin binding
F0005524molecular_functionATP binding
F0005737cellular_componentcytoplasm
F0005856cellular_componentcytoskeleton
F0005865cellular_componentstriated muscle thin filament
F0005884cellular_componentactin filament
F0010628biological_processpositive regulation of gene expression
F0016787molecular_functionhydrolase activity
F0019904molecular_functionprotein domain specific binding
F0030027cellular_componentlamellipodium
F0030041biological_processactin filament polymerization
F0030175cellular_componentfilopodium
F0030240biological_processskeletal muscle thin filament assembly
F0031013molecular_functiontroponin I binding
F0031432molecular_functiontitin binding
F0031941cellular_componentfilamentous actin
F0032036molecular_functionmyosin heavy chain binding
F0032432cellular_componentactin filament bundle
F0042802molecular_functionidentical protein binding
F0044297cellular_componentcell body
F0048306molecular_functioncalcium-dependent protein binding
F0048741biological_processskeletal muscle fiber development
F0051017biological_processactin filament bundle assembly
F0090131biological_processmesenchyme migration
F0098723cellular_componentskeletal muscle myofibril
F0140660molecular_functioncytoskeletal motor activator activity
g0001725cellular_componentstress fiber
g0003065biological_processpositive regulation of heart rate by epinephrine
g0003779molecular_functionactin binding
g0005200molecular_functionstructural constituent of cytoskeleton
g0005515molecular_functionprotein binding
g0005737cellular_componentcytoplasm
g0005829cellular_componentcytosol
g0005856cellular_componentcytoskeleton
g0005862cellular_componentmuscle thin filament tropomyosin
g0005884cellular_componentactin filament
g0006937biological_processregulation of muscle contraction
g0007010biological_processcytoskeleton organization
g0007015biological_processactin filament organization
g0008016biological_processregulation of heart contraction
g0008092molecular_functioncytoskeletal protein binding
g0008307molecular_functionstructural constituent of muscle
g0008360biological_processregulation of cell shape
g0015629cellular_componentactin cytoskeleton
g0030017cellular_componentsarcomere
g0030049biological_processmuscle filament sliding
g0030336biological_processnegative regulation of cell migration
g0031529biological_processruffle organization
g0032059cellular_componentbleb
g0032587cellular_componentruffle membrane
g0032781biological_processpositive regulation of ATP-dependent activity
g0034614biological_processcellular response to reactive oxygen species
g0042060biological_processwound healing
g0042802molecular_functionidentical protein binding
g0042803molecular_functionprotein homodimerization activity
g0045214biological_processsarcomere organization
g0045785biological_processpositive regulation of cell adhesion
g0046982molecular_functionprotein heterodimerization activity
g0051015molecular_functionactin filament binding
g0051496biological_processpositive regulation of stress fiber assembly
g0055010biological_processventricular cardiac muscle tissue morphogenesis
g0060048biological_processcardiac muscle contraction
g1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
g1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
G0000287molecular_functionmagnesium ion binding
G0001725cellular_componentstress fiber
G0003785molecular_functionactin monomer binding
G0005509molecular_functioncalcium ion binding
G0005515molecular_functionprotein binding
G0005523molecular_functiontropomyosin binding
G0005524molecular_functionATP binding
G0005737cellular_componentcytoplasm
G0005856cellular_componentcytoskeleton
G0005865cellular_componentstriated muscle thin filament
G0005884cellular_componentactin filament
G0010628biological_processpositive regulation of gene expression
G0016787molecular_functionhydrolase activity
G0019904molecular_functionprotein domain specific binding
G0030027cellular_componentlamellipodium
G0030041biological_processactin filament polymerization
G0030175cellular_componentfilopodium
G0030240biological_processskeletal muscle thin filament assembly
G0031013molecular_functiontroponin I binding
G0031432molecular_functiontitin binding
G0031941cellular_componentfilamentous actin
G0032036molecular_functionmyosin heavy chain binding
G0032432cellular_componentactin filament bundle
G0042802molecular_functionidentical protein binding
G0044297cellular_componentcell body
G0048306molecular_functioncalcium-dependent protein binding
G0048741biological_processskeletal muscle fiber development
G0051017biological_processactin filament bundle assembly
G0090131biological_processmesenchyme migration
G0098723cellular_componentskeletal muscle myofibril
G0140660molecular_functioncytoskeletal motor activator activity
h0001725cellular_componentstress fiber
h0003065biological_processpositive regulation of heart rate by epinephrine
h0003779molecular_functionactin binding
h0005200molecular_functionstructural constituent of cytoskeleton
h0005515molecular_functionprotein binding
h0005737cellular_componentcytoplasm
h0005829cellular_componentcytosol
h0005856cellular_componentcytoskeleton
h0005862cellular_componentmuscle thin filament tropomyosin
h0005884cellular_componentactin filament
h0006937biological_processregulation of muscle contraction
h0007010biological_processcytoskeleton organization
h0007015biological_processactin filament organization
h0008016biological_processregulation of heart contraction
h0008092molecular_functioncytoskeletal protein binding
h0008307molecular_functionstructural constituent of muscle
h0008360biological_processregulation of cell shape
h0015629cellular_componentactin cytoskeleton
h0030017cellular_componentsarcomere
h0030049biological_processmuscle filament sliding
h0030336biological_processnegative regulation of cell migration
h0031529biological_processruffle organization
h0032059cellular_componentbleb
h0032587cellular_componentruffle membrane
h0032781biological_processpositive regulation of ATP-dependent activity
h0034614biological_processcellular response to reactive oxygen species
h0042060biological_processwound healing
h0042802molecular_functionidentical protein binding
h0042803molecular_functionprotein homodimerization activity
h0045214biological_processsarcomere organization
h0045785biological_processpositive regulation of cell adhesion
h0046982molecular_functionprotein heterodimerization activity
h0051015molecular_functionactin filament binding
h0051496biological_processpositive regulation of stress fiber assembly
h0055010biological_processventricular cardiac muscle tissue morphogenesis
h0060048biological_processcardiac muscle contraction
h1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
h1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
H0000287molecular_functionmagnesium ion binding
H0001725cellular_componentstress fiber
H0003785molecular_functionactin monomer binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005523molecular_functiontropomyosin binding
H0005524molecular_functionATP binding
H0005737cellular_componentcytoplasm
H0005856cellular_componentcytoskeleton
H0005865cellular_componentstriated muscle thin filament
H0005884cellular_componentactin filament
H0010628biological_processpositive regulation of gene expression
H0016787molecular_functionhydrolase activity
H0019904molecular_functionprotein domain specific binding
H0030027cellular_componentlamellipodium
H0030041biological_processactin filament polymerization
H0030175cellular_componentfilopodium
H0030240biological_processskeletal muscle thin filament assembly
H0031013molecular_functiontroponin I binding
H0031432molecular_functiontitin binding
H0031941cellular_componentfilamentous actin
H0032036molecular_functionmyosin heavy chain binding
H0032432cellular_componentactin filament bundle
H0042802molecular_functionidentical protein binding
H0044297cellular_componentcell body
H0048306molecular_functioncalcium-dependent protein binding
H0048741biological_processskeletal muscle fiber development
H0051017biological_processactin filament bundle assembly
H0090131biological_processmesenchyme migration
H0098723cellular_componentskeletal muscle myofibril
H0140660molecular_functioncytoskeletal motor activator activity
i0001725cellular_componentstress fiber
i0003065biological_processpositive regulation of heart rate by epinephrine
i0003779molecular_functionactin binding
i0005200molecular_functionstructural constituent of cytoskeleton
i0005515molecular_functionprotein binding
i0005737cellular_componentcytoplasm
i0005829cellular_componentcytosol
i0005856cellular_componentcytoskeleton
i0005862cellular_componentmuscle thin filament tropomyosin
i0005884cellular_componentactin filament
i0006937biological_processregulation of muscle contraction
i0007010biological_processcytoskeleton organization
i0007015biological_processactin filament organization
i0008016biological_processregulation of heart contraction
i0008092molecular_functioncytoskeletal protein binding
i0008307molecular_functionstructural constituent of muscle
i0008360biological_processregulation of cell shape
i0015629cellular_componentactin cytoskeleton
i0030017cellular_componentsarcomere
i0030049biological_processmuscle filament sliding
i0030336biological_processnegative regulation of cell migration
i0031529biological_processruffle organization
i0032059cellular_componentbleb
i0032587cellular_componentruffle membrane
i0032781biological_processpositive regulation of ATP-dependent activity
i0034614biological_processcellular response to reactive oxygen species
i0042060biological_processwound healing
i0042802molecular_functionidentical protein binding
i0042803molecular_functionprotein homodimerization activity
i0045214biological_processsarcomere organization
i0045785biological_processpositive regulation of cell adhesion
i0046982molecular_functionprotein heterodimerization activity
i0051015molecular_functionactin filament binding
i0051496biological_processpositive regulation of stress fiber assembly
i0055010biological_processventricular cardiac muscle tissue morphogenesis
i0060048biological_processcardiac muscle contraction
i1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
i1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
I0000287molecular_functionmagnesium ion binding
I0001725cellular_componentstress fiber
I0003785molecular_functionactin monomer binding
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005523molecular_functiontropomyosin binding
I0005524molecular_functionATP binding
I0005737cellular_componentcytoplasm
I0005856cellular_componentcytoskeleton
I0005865cellular_componentstriated muscle thin filament
I0005884cellular_componentactin filament
I0010628biological_processpositive regulation of gene expression
I0016787molecular_functionhydrolase activity
I0019904molecular_functionprotein domain specific binding
I0030027cellular_componentlamellipodium
I0030041biological_processactin filament polymerization
I0030175cellular_componentfilopodium
I0030240biological_processskeletal muscle thin filament assembly
I0031013molecular_functiontroponin I binding
I0031432molecular_functiontitin binding
I0031941cellular_componentfilamentous actin
I0032036molecular_functionmyosin heavy chain binding
I0032432cellular_componentactin filament bundle
I0042802molecular_functionidentical protein binding
I0044297cellular_componentcell body
I0048306molecular_functioncalcium-dependent protein binding
I0048741biological_processskeletal muscle fiber development
I0051017biological_processactin filament bundle assembly
I0090131biological_processmesenchyme migration
I0098723cellular_componentskeletal muscle myofibril
I0140660molecular_functioncytoskeletal motor activator activity
j0001725cellular_componentstress fiber
j0003065biological_processpositive regulation of heart rate by epinephrine
j0003779molecular_functionactin binding
j0005200molecular_functionstructural constituent of cytoskeleton
j0005515molecular_functionprotein binding
j0005737cellular_componentcytoplasm
j0005829cellular_componentcytosol
j0005856cellular_componentcytoskeleton
j0005862cellular_componentmuscle thin filament tropomyosin
j0005884cellular_componentactin filament
j0006937biological_processregulation of muscle contraction
j0007010biological_processcytoskeleton organization
j0007015biological_processactin filament organization
j0008016biological_processregulation of heart contraction
j0008092molecular_functioncytoskeletal protein binding
j0008307molecular_functionstructural constituent of muscle
j0008360biological_processregulation of cell shape
j0015629cellular_componentactin cytoskeleton
j0030017cellular_componentsarcomere
j0030049biological_processmuscle filament sliding
j0030336biological_processnegative regulation of cell migration
j0031529biological_processruffle organization
j0032059cellular_componentbleb
j0032587cellular_componentruffle membrane
j0032781biological_processpositive regulation of ATP-dependent activity
j0034614biological_processcellular response to reactive oxygen species
j0042060biological_processwound healing
j0042802molecular_functionidentical protein binding
j0042803molecular_functionprotein homodimerization activity
j0045214biological_processsarcomere organization
j0045785biological_processpositive regulation of cell adhesion
j0046982molecular_functionprotein heterodimerization activity
j0051015molecular_functionactin filament binding
j0051496biological_processpositive regulation of stress fiber assembly
j0055010biological_processventricular cardiac muscle tissue morphogenesis
j0060048biological_processcardiac muscle contraction
j1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
j1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
J0000287molecular_functionmagnesium ion binding
J0001725cellular_componentstress fiber
J0003785molecular_functionactin monomer binding
J0005509molecular_functioncalcium ion binding
J0005515molecular_functionprotein binding
J0005523molecular_functiontropomyosin binding
J0005524molecular_functionATP binding
J0005737cellular_componentcytoplasm
J0005856cellular_componentcytoskeleton
J0005865cellular_componentstriated muscle thin filament
J0005884cellular_componentactin filament
J0010628biological_processpositive regulation of gene expression
J0016787molecular_functionhydrolase activity
J0019904molecular_functionprotein domain specific binding
J0030027cellular_componentlamellipodium
J0030041biological_processactin filament polymerization
J0030175cellular_componentfilopodium
J0030240biological_processskeletal muscle thin filament assembly
J0031013molecular_functiontroponin I binding
J0031432molecular_functiontitin binding
J0031941cellular_componentfilamentous actin
J0032036molecular_functionmyosin heavy chain binding
J0032432cellular_componentactin filament bundle
J0042802molecular_functionidentical protein binding
J0044297cellular_componentcell body
J0048306molecular_functioncalcium-dependent protein binding
J0048741biological_processskeletal muscle fiber development
J0051017biological_processactin filament bundle assembly
J0090131biological_processmesenchyme migration
J0098723cellular_componentskeletal muscle myofibril
J0140660molecular_functioncytoskeletal motor activator activity
K0000287molecular_functionmagnesium ion binding
K0001725cellular_componentstress fiber
K0003785molecular_functionactin monomer binding
K0005509molecular_functioncalcium ion binding
K0005515molecular_functionprotein binding
K0005523molecular_functiontropomyosin binding
K0005524molecular_functionATP binding
K0005737cellular_componentcytoplasm
K0005856cellular_componentcytoskeleton
K0005865cellular_componentstriated muscle thin filament
K0005884cellular_componentactin filament
K0010628biological_processpositive regulation of gene expression
K0016787molecular_functionhydrolase activity
K0019904molecular_functionprotein domain specific binding
K0030027cellular_componentlamellipodium
K0030041biological_processactin filament polymerization
K0030175cellular_componentfilopodium
K0030240biological_processskeletal muscle thin filament assembly
K0031013molecular_functiontroponin I binding
K0031432molecular_functiontitin binding
K0031941cellular_componentfilamentous actin
K0032036molecular_functionmyosin heavy chain binding
K0032432cellular_componentactin filament bundle
K0042802molecular_functionidentical protein binding
K0044297cellular_componentcell body
K0048306molecular_functioncalcium-dependent protein binding
K0048741biological_processskeletal muscle fiber development
K0051017biological_processactin filament bundle assembly
K0090131biological_processmesenchyme migration
K0098723cellular_componentskeletal muscle myofibril
K0140660molecular_functioncytoskeletal motor activator activity
L0000287molecular_functionmagnesium ion binding
L0001725cellular_componentstress fiber
L0003785molecular_functionactin monomer binding
L0005509molecular_functioncalcium ion binding
L0005515molecular_functionprotein binding
L0005523molecular_functiontropomyosin binding
L0005524molecular_functionATP binding
L0005737cellular_componentcytoplasm
L0005856cellular_componentcytoskeleton
L0005865cellular_componentstriated muscle thin filament
L0005884cellular_componentactin filament
L0010628biological_processpositive regulation of gene expression
L0016787molecular_functionhydrolase activity
L0019904molecular_functionprotein domain specific binding
L0030027cellular_componentlamellipodium
L0030041biological_processactin filament polymerization
L0030175cellular_componentfilopodium
L0030240biological_processskeletal muscle thin filament assembly
L0031013molecular_functiontroponin I binding
L0031432molecular_functiontitin binding
L0031941cellular_componentfilamentous actin
L0032036molecular_functionmyosin heavy chain binding
L0032432cellular_componentactin filament bundle
L0042802molecular_functionidentical protein binding
L0044297cellular_componentcell body
L0048306molecular_functioncalcium-dependent protein binding
L0048741biological_processskeletal muscle fiber development
L0051017biological_processactin filament bundle assembly
L0090131biological_processmesenchyme migration
L0098723cellular_componentskeletal muscle myofibril
L0140660molecular_functioncytoskeletal motor activator activity
M0000287molecular_functionmagnesium ion binding
M0001725cellular_componentstress fiber
M0003785molecular_functionactin monomer binding
M0005509molecular_functioncalcium ion binding
M0005515molecular_functionprotein binding
M0005523molecular_functiontropomyosin binding
M0005524molecular_functionATP binding
M0005737cellular_componentcytoplasm
M0005856cellular_componentcytoskeleton
M0005865cellular_componentstriated muscle thin filament
M0005884cellular_componentactin filament
M0010628biological_processpositive regulation of gene expression
M0016787molecular_functionhydrolase activity
M0019904molecular_functionprotein domain specific binding
M0030027cellular_componentlamellipodium
M0030041biological_processactin filament polymerization
M0030175cellular_componentfilopodium
M0030240biological_processskeletal muscle thin filament assembly
M0031013molecular_functiontroponin I binding
M0031432molecular_functiontitin binding
M0031941cellular_componentfilamentous actin
M0032036molecular_functionmyosin heavy chain binding
M0032432cellular_componentactin filament bundle
M0042802molecular_functionidentical protein binding
M0044297cellular_componentcell body
M0048306molecular_functioncalcium-dependent protein binding
M0048741biological_processskeletal muscle fiber development
M0051017biological_processactin filament bundle assembly
M0090131biological_processmesenchyme migration
M0098723cellular_componentskeletal muscle myofibril
M0140660molecular_functioncytoskeletal motor activator activity
N0000287molecular_functionmagnesium ion binding
N0001725cellular_componentstress fiber
N0003785molecular_functionactin monomer binding
N0005509molecular_functioncalcium ion binding
N0005515molecular_functionprotein binding
N0005523molecular_functiontropomyosin binding
N0005524molecular_functionATP binding
N0005737cellular_componentcytoplasm
N0005856cellular_componentcytoskeleton
N0005865cellular_componentstriated muscle thin filament
N0005884cellular_componentactin filament
N0010628biological_processpositive regulation of gene expression
N0016787molecular_functionhydrolase activity
N0019904molecular_functionprotein domain specific binding
N0030027cellular_componentlamellipodium
N0030041biological_processactin filament polymerization
N0030175cellular_componentfilopodium
N0030240biological_processskeletal muscle thin filament assembly
N0031013molecular_functiontroponin I binding
N0031432molecular_functiontitin binding
N0031941cellular_componentfilamentous actin
N0032036molecular_functionmyosin heavy chain binding
N0032432cellular_componentactin filament bundle
N0042802molecular_functionidentical protein binding
N0044297cellular_componentcell body
N0048306molecular_functioncalcium-dependent protein binding
N0048741biological_processskeletal muscle fiber development
N0051017biological_processactin filament bundle assembly
N0090131biological_processmesenchyme migration
N0098723cellular_componentskeletal muscle myofibril
N0140660molecular_functioncytoskeletal motor activator activity
O0000287molecular_functionmagnesium ion binding
O0001725cellular_componentstress fiber
O0003785molecular_functionactin monomer binding
O0005509molecular_functioncalcium ion binding
O0005515molecular_functionprotein binding
O0005523molecular_functiontropomyosin binding
O0005524molecular_functionATP binding
O0005737cellular_componentcytoplasm
O0005856cellular_componentcytoskeleton
O0005865cellular_componentstriated muscle thin filament
O0005884cellular_componentactin filament
O0010628biological_processpositive regulation of gene expression
O0016787molecular_functionhydrolase activity
O0019904molecular_functionprotein domain specific binding
O0030027cellular_componentlamellipodium
O0030041biological_processactin filament polymerization
O0030175cellular_componentfilopodium
O0030240biological_processskeletal muscle thin filament assembly
O0031013molecular_functiontroponin I binding
O0031432molecular_functiontitin binding
O0031941cellular_componentfilamentous actin
O0032036molecular_functionmyosin heavy chain binding
O0032432cellular_componentactin filament bundle
O0042802molecular_functionidentical protein binding
O0044297cellular_componentcell body
O0048306molecular_functioncalcium-dependent protein binding
O0048741biological_processskeletal muscle fiber development
O0051017biological_processactin filament bundle assembly
O0090131biological_processmesenchyme migration
O0098723cellular_componentskeletal muscle myofibril
O0140660molecular_functioncytoskeletal motor activator activity
P0000287molecular_functionmagnesium ion binding
P0001725cellular_componentstress fiber
P0003785molecular_functionactin monomer binding
P0005509molecular_functioncalcium ion binding
P0005515molecular_functionprotein binding
P0005523molecular_functiontropomyosin binding
P0005524molecular_functionATP binding
P0005737cellular_componentcytoplasm
P0005856cellular_componentcytoskeleton
P0005865cellular_componentstriated muscle thin filament
P0005884cellular_componentactin filament
P0010628biological_processpositive regulation of gene expression
P0016787molecular_functionhydrolase activity
P0019904molecular_functionprotein domain specific binding
P0030027cellular_componentlamellipodium
P0030041biological_processactin filament polymerization
P0030175cellular_componentfilopodium
P0030240biological_processskeletal muscle thin filament assembly
P0031013molecular_functiontroponin I binding
P0031432molecular_functiontitin binding
P0031941cellular_componentfilamentous actin
P0032036molecular_functionmyosin heavy chain binding
P0032432cellular_componentactin filament bundle
P0042802molecular_functionidentical protein binding
P0044297cellular_componentcell body
P0048306molecular_functioncalcium-dependent protein binding
P0048741biological_processskeletal muscle fiber development
P0051017biological_processactin filament bundle assembly
P0090131biological_processmesenchyme migration
P0098723cellular_componentskeletal muscle myofibril
P0140660molecular_functioncytoskeletal motor activator activity
Q0000287molecular_functionmagnesium ion binding
Q0001725cellular_componentstress fiber
Q0003785molecular_functionactin monomer binding
Q0005509molecular_functioncalcium ion binding
Q0005515molecular_functionprotein binding
Q0005523molecular_functiontropomyosin binding
Q0005524molecular_functionATP binding
Q0005737cellular_componentcytoplasm
Q0005856cellular_componentcytoskeleton
Q0005865cellular_componentstriated muscle thin filament
Q0005884cellular_componentactin filament
Q0010628biological_processpositive regulation of gene expression
Q0016787molecular_functionhydrolase activity
Q0019904molecular_functionprotein domain specific binding
Q0030027cellular_componentlamellipodium
Q0030041biological_processactin filament polymerization
Q0030175cellular_componentfilopodium
Q0030240biological_processskeletal muscle thin filament assembly
Q0031013molecular_functiontroponin I binding
Q0031432molecular_functiontitin binding
Q0031941cellular_componentfilamentous actin
Q0032036molecular_functionmyosin heavy chain binding
Q0032432cellular_componentactin filament bundle
Q0042802molecular_functionidentical protein binding
Q0044297cellular_componentcell body
Q0048306molecular_functioncalcium-dependent protein binding
Q0048741biological_processskeletal muscle fiber development
Q0051017biological_processactin filament bundle assembly
Q0090131biological_processmesenchyme migration
Q0098723cellular_componentskeletal muscle myofibril
Q0140660molecular_functioncytoskeletal motor activator activity
R0000287molecular_functionmagnesium ion binding
R0001725cellular_componentstress fiber
R0003785molecular_functionactin monomer binding
R0005509molecular_functioncalcium ion binding
R0005515molecular_functionprotein binding
R0005523molecular_functiontropomyosin binding
R0005524molecular_functionATP binding
R0005737cellular_componentcytoplasm
R0005856cellular_componentcytoskeleton
R0005865cellular_componentstriated muscle thin filament
R0005884cellular_componentactin filament
R0010628biological_processpositive regulation of gene expression
R0016787molecular_functionhydrolase activity
R0019904molecular_functionprotein domain specific binding
R0030027cellular_componentlamellipodium
R0030041biological_processactin filament polymerization
R0030175cellular_componentfilopodium
R0030240biological_processskeletal muscle thin filament assembly
R0031013molecular_functiontroponin I binding
R0031432molecular_functiontitin binding
R0031941cellular_componentfilamentous actin
R0032036molecular_functionmyosin heavy chain binding
R0032432cellular_componentactin filament bundle
R0042802molecular_functionidentical protein binding
R0044297cellular_componentcell body
R0048306molecular_functioncalcium-dependent protein binding
R0048741biological_processskeletal muscle fiber development
R0051017biological_processactin filament bundle assembly
R0090131biological_processmesenchyme migration
R0098723cellular_componentskeletal muscle myofibril
R0140660molecular_functioncytoskeletal motor activator activity
U0002086biological_processdiaphragm contraction
U0003009biological_processskeletal muscle contraction
U0005509molecular_functioncalcium ion binding
U0005515molecular_functionprotein binding
U0005829cellular_componentcytosol
U0005861cellular_componenttroponin complex
U0006937biological_processregulation of muscle contraction
U0010038biological_processresponse to metal ion
U0014883biological_processtransition between fast and slow fiber
U0031013molecular_functiontroponin I binding
U0031014molecular_functiontroponin T binding
U0032972biological_processregulation of muscle filament sliding speed
U0042803molecular_functionprotein homodimerization activity
U0043292cellular_componentcontractile muscle fiber
U0043462biological_processregulation of ATP-dependent activity
U0046872molecular_functionmetal ion binding
U0048306molecular_functioncalcium-dependent protein binding
U0051015molecular_functionactin filament binding
U0055010biological_processventricular cardiac muscle tissue morphogenesis
U0060048biological_processcardiac muscle contraction
U1990584cellular_componentcardiac Troponin complex
V0001570biological_processvasculogenesis
V0001980biological_processregulation of systemic arterial blood pressure by ischemic conditions
V0003009biological_processskeletal muscle contraction
V0003779molecular_functionactin binding
V0005515molecular_functionprotein binding
V0005737cellular_componentcytoplasm
V0005829cellular_componentcytosol
V0005861cellular_componenttroponin complex
V0006874biological_processintracellular calcium ion homeostasis
V0006937biological_processregulation of muscle contraction
V0006940biological_processregulation of smooth muscle contraction
V0006941biological_processstriated muscle contraction
V0007507biological_processheart development
V0010882biological_processregulation of cardiac muscle contraction by calcium ion signaling
V0019855molecular_functioncalcium channel inhibitor activity
V0019901molecular_functionprotein kinase binding
V0019904molecular_functionprotein domain specific binding
V0030016cellular_componentmyofibril
V0030017cellular_componentsarcomere
V0030172molecular_functiontroponin C binding
V0031014molecular_functiontroponin T binding
V0032780biological_processnegative regulation of ATP-dependent activity
V0043292cellular_componentcontractile muscle fiber
V0048306molecular_functioncalcium-dependent protein binding
V0051015molecular_functionactin filament binding
V0055010biological_processventricular cardiac muscle tissue morphogenesis
V0060047biological_processheart contraction
V0060048biological_processcardiac muscle contraction
V0097512cellular_componentcardiac myofibril
V1990584cellular_componentcardiac Troponin complex
W0001725cellular_componentstress fiber
W0003065biological_processpositive regulation of heart rate by epinephrine
W0003779molecular_functionactin binding
W0005200molecular_functionstructural constituent of cytoskeleton
W0005515molecular_functionprotein binding
W0005737cellular_componentcytoplasm
W0005829cellular_componentcytosol
W0005856cellular_componentcytoskeleton
W0005862cellular_componentmuscle thin filament tropomyosin
W0005884cellular_componentactin filament
W0006937biological_processregulation of muscle contraction
W0007010biological_processcytoskeleton organization
W0007015biological_processactin filament organization
W0008016biological_processregulation of heart contraction
W0008092molecular_functioncytoskeletal protein binding
W0008307molecular_functionstructural constituent of muscle
W0008360biological_processregulation of cell shape
W0015629cellular_componentactin cytoskeleton
W0030017cellular_componentsarcomere
W0030049biological_processmuscle filament sliding
W0030336biological_processnegative regulation of cell migration
W0031529biological_processruffle organization
W0032059cellular_componentbleb
W0032587cellular_componentruffle membrane
W0032781biological_processpositive regulation of ATP-dependent activity
W0034614biological_processcellular response to reactive oxygen species
W0042060biological_processwound healing
W0042802molecular_functionidentical protein binding
W0042803molecular_functionprotein homodimerization activity
W0045214biological_processsarcomere organization
W0045785biological_processpositive regulation of cell adhesion
W0046982molecular_functionprotein heterodimerization activity
W0051015molecular_functionactin filament binding
W0051496biological_processpositive regulation of stress fiber assembly
W0055010biological_processventricular cardiac muscle tissue morphogenesis
W0060048biological_processcardiac muscle contraction
W1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
W1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
X0003779molecular_functionactin binding
X0005515molecular_functionprotein binding
X0005523molecular_functiontropomyosin binding
X0005829cellular_componentcytosol
X0005861cellular_componenttroponin complex
X0005865cellular_componentstriated muscle thin filament
X0006937biological_processregulation of muscle contraction
X0008016biological_processregulation of heart contraction
X0030017cellular_componentsarcomere
X0030049biological_processmuscle filament sliding
X0030172molecular_functiontroponin C binding
X0031013molecular_functiontroponin I binding
X0032780biological_processnegative regulation of ATP-dependent activity
X0032781biological_processpositive regulation of ATP-dependent activity
X0045214biological_processsarcomere organization
X0051592biological_processresponse to calcium ion
X0055010biological_processventricular cardiac muscle tissue morphogenesis
X0060048biological_processcardiac muscle contraction
X0097512cellular_componentcardiac myofibril
X1990584cellular_componentcardiac Troponin complex
Y0003779molecular_functionactin binding
Y0005515molecular_functionprotein binding
Y0005523molecular_functiontropomyosin binding
Y0005829cellular_componentcytosol
Y0005861cellular_componenttroponin complex
Y0005865cellular_componentstriated muscle thin filament
Y0006937biological_processregulation of muscle contraction
Y0008016biological_processregulation of heart contraction
Y0030017cellular_componentsarcomere
Y0030049biological_processmuscle filament sliding
Y0030172molecular_functiontroponin C binding
Y0031013molecular_functiontroponin I binding
Y0032780biological_processnegative regulation of ATP-dependent activity
Y0032781biological_processpositive regulation of ATP-dependent activity
Y0045214biological_processsarcomere organization
Y0051592biological_processresponse to calcium ion
Y0055010biological_processventricular cardiac muscle tissue morphogenesis
Y0060048biological_processcardiac muscle contraction
Y0097512cellular_componentcardiac myofibril
Y1990584cellular_componentcardiac Troponin complex
Z0001725cellular_componentstress fiber
Z0003065biological_processpositive regulation of heart rate by epinephrine
Z0003779molecular_functionactin binding
Z0005200molecular_functionstructural constituent of cytoskeleton
Z0005515molecular_functionprotein binding
Z0005737cellular_componentcytoplasm
Z0005829cellular_componentcytosol
Z0005856cellular_componentcytoskeleton
Z0005862cellular_componentmuscle thin filament tropomyosin
Z0005884cellular_componentactin filament
Z0006937biological_processregulation of muscle contraction
Z0007010biological_processcytoskeleton organization
Z0007015biological_processactin filament organization
Z0008016biological_processregulation of heart contraction
Z0008092molecular_functioncytoskeletal protein binding
Z0008307molecular_functionstructural constituent of muscle
Z0008360biological_processregulation of cell shape
Z0015629cellular_componentactin cytoskeleton
Z0030017cellular_componentsarcomere
Z0030049biological_processmuscle filament sliding
Z0030336biological_processnegative regulation of cell migration
Z0031529biological_processruffle organization
Z0032059cellular_componentbleb
Z0032587cellular_componentruffle membrane
Z0032781biological_processpositive regulation of ATP-dependent activity
Z0034614biological_processcellular response to reactive oxygen species
Z0042060biological_processwound healing
Z0042802molecular_functionidentical protein binding
Z0042803molecular_functionprotein homodimerization activity
Z0045214biological_processsarcomere organization
Z0045785biological_processpositive regulation of cell adhesion
Z0046982molecular_functionprotein heterodimerization activity
Z0051015molecular_functionactin filament binding
Z0051496biological_processpositive regulation of stress fiber assembly
Z0055010biological_processventricular cardiac muscle tissue morphogenesis
Z0060048biological_processcardiac muscle contraction
Z1904706biological_processnegative regulation of vascular associated smooth muscle cell proliferation
Z1904753biological_processnegative regulation of vascular associated smooth muscle cell migration
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DEDGSGTVDfdEF
ChainResidueDetails
dASP65-PHE77
dASP105-LEU117
dASP141-PHE153

site_idPS00326
Number of Residues9
DetailsTROPOMYOSIN Tropomyosins signature. LKEAEtRAE
ChainResidueDetails
iLEU232-GLU240

site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
ATYR53-GLY63

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WITKqEYDE
ChainResidueDetails
ATRP356-GLU364

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
ChainResidueDetails
ALEU104-ARG116

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues30
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448
ChainResidueDetails
UASP65
UGLU116
UASP141
UASN143
UASP145
UARG147
UGLU152
dASP65
dASP67
dSER69
dTHR71
UASP67
dGLU76
dASP105
dASN107
dASP109
dTYR111
dGLU116
dASP141
dASN143
dASP145
dARG147
USER69
dGLU152
UTHR71
UGLU76
UASP105
UASN107
UASP109
UTYR111

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylmethionine => ECO:0000269|PubMed:3951483
ChainResidueDetails
UMET1
JASP1
KASP1
LASP1
MASP1
NASP1
OASP1
PASP1
QASP1
RASP1
dMET1
eGLU204
fGLU204
iSER45
jSER45
gSER45
hSER45
IASP1

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P19123
ChainResidueDetails
USER98
cSER199
FMET44
FMET47
GMET44
GMET47
HMET44
HMET47
IMET44
IMET47
JMET44
dSER98
JMET47
KMET44
KMET47
LMET44
LMET47
MMET44
MMET47
NMET44
NMET47
OMET44
VSER77
OMET47
PMET44
PMET47
QMET44
QMET47
RMET44
RMET47
VSER166
VSER199
cSER5
cSER6
cSER77
cSER166

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKA and PKD/PRKD1 => ECO:0000269|PubMed:15514163, ECO:0000269|PubMed:2226863, ECO:0000269|PubMed:22972900, ECO:0000269|PubMed:9346285
ChainResidueDetails
VSER23
WSER206
WSER252
WSER271
ZSER186
ZSER206
ZSER252
ZSER271
iSER186
iSER206
iSER252
VSER24
iSER271
jSER186
jSER206
jSER252
jSER271
gSER186
gSER206
gSER252
gSER271
hSER186
cSER23
hSER206
hSER252
hSER271
cSER24
bSER186
bSER206
bSER252
bSER271
WSER186

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0000269|PubMed:22972900
ChainResidueDetails
VTYR26
JHIC73
KHIC73
LHIC73
MHIC73
NHIC73
OHIC73
PHIC73
QHIC73
RHIC73
cTYR26
WTYR261
ZTYR261
iTYR261
jTYR261
gTYR261
hTYR261
IHIC73

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: Phosphothreonine; by STK4/MST1 => ECO:0000269|PubMed:18986304
ChainResidueDetails
VTHR31
JLYS84
KLYS84
LLYS84
MLYS84
NLYS84
OLYS84
PLYS84
QLYS84
RLYS84
VTHR129
cTHR31
cTHR129
iSER283
jSER283
gSER283
hSER283
ILYS84

site_idSWS_FT_FI7
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKC/PRKCE => ECO:0000250|UniProtKB:P48787
ChainResidueDetails
VSER42
JARG177
KARG177
LARG177
MARG177
NARG177
OARG177
PARG177
QARG177
RARG177
VSER44
cSER42
cSER44
EARG177
FARG177
GARG177
HARG177
IARG177

site_idSWS_FT_FI8
Number of Residues4
DetailsMOD_RES: Phosphothreonine; by STK4/MST1 => ECO:0000269|PubMed:18986304, ECO:0000269|PubMed:22972900
ChainResidueDetails
VTHR51
VTHR143
cTHR51
cTHR143

site_idSWS_FT_FI9
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0000269|PubMed:22972900
ChainResidueDetails
VTHR78
VTHR181
cTHR78
cTHR181

site_idSWS_FT_FI10
Number of Residues2
DetailsMOD_RES: Phosphoserine; by PAK3 => ECO:0000269|PubMed:12242269
ChainResidueDetails
VSER150
cSER150

222926

PDB entries from 2024-07-24

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