7USY
Structure of C. elegans TMC-1 complex with ARRD-6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005272 | molecular_function | sodium channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0007606 | biological_process | sensory perception of chemical stimulus |
| A | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0035725 | biological_process | sodium ion transmembrane transport |
| A | 0043025 | cellular_component | neuronal cell body |
| A | 0050906 | biological_process | detection of stimulus involved in sensory perception |
| A | 0097730 | cellular_component | non-motile cilium |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005272 | molecular_function | sodium channel activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0007606 | biological_process | sensory perception of chemical stimulus |
| B | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0035725 | biological_process | sodium ion transmembrane transport |
| B | 0043025 | cellular_component | neuronal cell body |
| B | 0050906 | biological_process | detection of stimulus involved in sensory perception |
| B | 0097730 | cellular_component | non-motile cilium |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0055074 | biological_process | calcium ion homeostasis |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0055120 | cellular_component | striated muscle dense body |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0005509 | molecular_function | calcium ion binding |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0055074 | biological_process | calcium ion homeostasis |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0055120 | cellular_component | striated muscle dense body |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0060090 | molecular_function | molecular adaptor activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 524 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"36224384","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7USW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 214 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 180 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 62 |
| Details | Region: {"description":"Required for interaction with tmie","evidences":[{"source":"PubMed","id":"36224384","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7USW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Site: {"description":"Required for interaction with calm-1","evidences":[{"source":"PubMed","id":"36224384","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7USW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GalNAc...) asparagine","evidences":[{"source":"PubMed","id":"36224384","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7USW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7USY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
