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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7UOM

Endogenous dihydrolipoamide acetyltransferase (E2) core of pyruvate dehydrogenase complex from bovine kidney

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
010004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
010005739cellular_componentmitochondrion
010005759cellular_componentmitochondrial matrix
010006006biological_processglucose metabolic process
010006086biological_processpyruvate decarboxylation to acetyl-CoA
010006090biological_processpyruvate metabolic process
010006099biological_processtricarboxylic acid cycle
010009060biological_processaerobic respiration
010016407molecular_functionacetyltransferase activity
010016740molecular_functiontransferase activity
010016746molecular_functionacyltransferase activity
010042802molecular_functionidentical protein binding
010042867biological_processpyruvate catabolic process
010045254cellular_componentpyruvate dehydrogenase complex
020004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
020005739cellular_componentmitochondrion
020005759cellular_componentmitochondrial matrix
020006006biological_processglucose metabolic process
020006086biological_processpyruvate decarboxylation to acetyl-CoA
020006090biological_processpyruvate metabolic process
020006099biological_processtricarboxylic acid cycle
020009060biological_processaerobic respiration
020016407molecular_functionacetyltransferase activity
020016740molecular_functiontransferase activity
020016746molecular_functionacyltransferase activity
020042802molecular_functionidentical protein binding
020042867biological_processpyruvate catabolic process
020045254cellular_componentpyruvate dehydrogenase complex
030004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
030005739cellular_componentmitochondrion
030005759cellular_componentmitochondrial matrix
030006006biological_processglucose metabolic process
030006086biological_processpyruvate decarboxylation to acetyl-CoA
030006090biological_processpyruvate metabolic process
030006099biological_processtricarboxylic acid cycle
030009060biological_processaerobic respiration
030016407molecular_functionacetyltransferase activity
030016740molecular_functiontransferase activity
030016746molecular_functionacyltransferase activity
030042802molecular_functionidentical protein binding
030042867biological_processpyruvate catabolic process
030045254cellular_componentpyruvate dehydrogenase complex
040004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
040005739cellular_componentmitochondrion
040005759cellular_componentmitochondrial matrix
040006006biological_processglucose metabolic process
040006086biological_processpyruvate decarboxylation to acetyl-CoA
040006090biological_processpyruvate metabolic process
040006099biological_processtricarboxylic acid cycle
040009060biological_processaerobic respiration
040016407molecular_functionacetyltransferase activity
040016740molecular_functiontransferase activity
040016746molecular_functionacyltransferase activity
040042802molecular_functionidentical protein binding
040042867biological_processpyruvate catabolic process
040045254cellular_componentpyruvate dehydrogenase complex
050004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
050005739cellular_componentmitochondrion
050005759cellular_componentmitochondrial matrix
050006006biological_processglucose metabolic process
050006086biological_processpyruvate decarboxylation to acetyl-CoA
050006090biological_processpyruvate metabolic process
050006099biological_processtricarboxylic acid cycle
050009060biological_processaerobic respiration
050016407molecular_functionacetyltransferase activity
050016740molecular_functiontransferase activity
050016746molecular_functionacyltransferase activity
050042802molecular_functionidentical protein binding
050042867biological_processpyruvate catabolic process
050045254cellular_componentpyruvate dehydrogenase complex
0z0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
0z0005739cellular_componentmitochondrion
0z0005759cellular_componentmitochondrial matrix
0z0006006biological_processglucose metabolic process
0z0006086biological_processpyruvate decarboxylation to acetyl-CoA
0z0006090biological_processpyruvate metabolic process
0z0006099biological_processtricarboxylic acid cycle
0z0009060biological_processaerobic respiration
0z0016407molecular_functionacetyltransferase activity
0z0016740molecular_functiontransferase activity
0z0016746molecular_functionacyltransferase activity
0z0042802molecular_functionidentical protein binding
0z0042867biological_processpyruvate catabolic process
0z0045254cellular_componentpyruvate dehydrogenase complex
1a0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1a0005739cellular_componentmitochondrion
1a0005759cellular_componentmitochondrial matrix
1a0006006biological_processglucose metabolic process
1a0006086biological_processpyruvate decarboxylation to acetyl-CoA
1a0006090biological_processpyruvate metabolic process
1a0006099biological_processtricarboxylic acid cycle
1a0009060biological_processaerobic respiration
1a0016407molecular_functionacetyltransferase activity
1a0016740molecular_functiontransferase activity
1a0016746molecular_functionacyltransferase activity
1a0042802molecular_functionidentical protein binding
1a0042867biological_processpyruvate catabolic process
1a0045254cellular_componentpyruvate dehydrogenase complex
1b0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1b0005739cellular_componentmitochondrion
1b0005759cellular_componentmitochondrial matrix
1b0006006biological_processglucose metabolic process
1b0006086biological_processpyruvate decarboxylation to acetyl-CoA
1b0006090biological_processpyruvate metabolic process
1b0006099biological_processtricarboxylic acid cycle
1b0009060biological_processaerobic respiration
1b0016407molecular_functionacetyltransferase activity
1b0016740molecular_functiontransferase activity
1b0016746molecular_functionacyltransferase activity
1b0042802molecular_functionidentical protein binding
1b0042867biological_processpyruvate catabolic process
1b0045254cellular_componentpyruvate dehydrogenase complex
1c0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1c0005739cellular_componentmitochondrion
1c0005759cellular_componentmitochondrial matrix
1c0006006biological_processglucose metabolic process
1c0006086biological_processpyruvate decarboxylation to acetyl-CoA
1c0006090biological_processpyruvate metabolic process
1c0006099biological_processtricarboxylic acid cycle
1c0009060biological_processaerobic respiration
1c0016407molecular_functionacetyltransferase activity
1c0016740molecular_functiontransferase activity
1c0016746molecular_functionacyltransferase activity
1c0042802molecular_functionidentical protein binding
1c0042867biological_processpyruvate catabolic process
1c0045254cellular_componentpyruvate dehydrogenase complex
1d0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1d0005739cellular_componentmitochondrion
1d0005759cellular_componentmitochondrial matrix
1d0006006biological_processglucose metabolic process
1d0006086biological_processpyruvate decarboxylation to acetyl-CoA
1d0006090biological_processpyruvate metabolic process
1d0006099biological_processtricarboxylic acid cycle
1d0009060biological_processaerobic respiration
1d0016407molecular_functionacetyltransferase activity
1d0016740molecular_functiontransferase activity
1d0016746molecular_functionacyltransferase activity
1d0042802molecular_functionidentical protein binding
1d0042867biological_processpyruvate catabolic process
1d0045254cellular_componentpyruvate dehydrogenase complex
1e0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1e0005739cellular_componentmitochondrion
1e0005759cellular_componentmitochondrial matrix
1e0006006biological_processglucose metabolic process
1e0006086biological_processpyruvate decarboxylation to acetyl-CoA
1e0006090biological_processpyruvate metabolic process
1e0006099biological_processtricarboxylic acid cycle
1e0009060biological_processaerobic respiration
1e0016407molecular_functionacetyltransferase activity
1e0016740molecular_functiontransferase activity
1e0016746molecular_functionacyltransferase activity
1e0042802molecular_functionidentical protein binding
1e0042867biological_processpyruvate catabolic process
1e0045254cellular_componentpyruvate dehydrogenase complex
1f0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1f0005739cellular_componentmitochondrion
1f0005759cellular_componentmitochondrial matrix
1f0006006biological_processglucose metabolic process
1f0006086biological_processpyruvate decarboxylation to acetyl-CoA
1f0006090biological_processpyruvate metabolic process
1f0006099biological_processtricarboxylic acid cycle
1f0009060biological_processaerobic respiration
1f0016407molecular_functionacetyltransferase activity
1f0016740molecular_functiontransferase activity
1f0016746molecular_functionacyltransferase activity
1f0042802molecular_functionidentical protein binding
1f0042867biological_processpyruvate catabolic process
1f0045254cellular_componentpyruvate dehydrogenase complex
1g0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1g0005739cellular_componentmitochondrion
1g0005759cellular_componentmitochondrial matrix
1g0006006biological_processglucose metabolic process
1g0006086biological_processpyruvate decarboxylation to acetyl-CoA
1g0006090biological_processpyruvate metabolic process
1g0006099biological_processtricarboxylic acid cycle
1g0009060biological_processaerobic respiration
1g0016407molecular_functionacetyltransferase activity
1g0016740molecular_functiontransferase activity
1g0016746molecular_functionacyltransferase activity
1g0042802molecular_functionidentical protein binding
1g0042867biological_processpyruvate catabolic process
1g0045254cellular_componentpyruvate dehydrogenase complex
1h0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1h0005739cellular_componentmitochondrion
1h0005759cellular_componentmitochondrial matrix
1h0006006biological_processglucose metabolic process
1h0006086biological_processpyruvate decarboxylation to acetyl-CoA
1h0006090biological_processpyruvate metabolic process
1h0006099biological_processtricarboxylic acid cycle
1h0009060biological_processaerobic respiration
1h0016407molecular_functionacetyltransferase activity
1h0016740molecular_functiontransferase activity
1h0016746molecular_functionacyltransferase activity
1h0042802molecular_functionidentical protein binding
1h0042867biological_processpyruvate catabolic process
1h0045254cellular_componentpyruvate dehydrogenase complex
1i0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1i0005739cellular_componentmitochondrion
1i0005759cellular_componentmitochondrial matrix
1i0006006biological_processglucose metabolic process
1i0006086biological_processpyruvate decarboxylation to acetyl-CoA
1i0006090biological_processpyruvate metabolic process
1i0006099biological_processtricarboxylic acid cycle
1i0009060biological_processaerobic respiration
1i0016407molecular_functionacetyltransferase activity
1i0016740molecular_functiontransferase activity
1i0016746molecular_functionacyltransferase activity
1i0042802molecular_functionidentical protein binding
1i0042867biological_processpyruvate catabolic process
1i0045254cellular_componentpyruvate dehydrogenase complex
1j0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1j0005739cellular_componentmitochondrion
1j0005759cellular_componentmitochondrial matrix
1j0006006biological_processglucose metabolic process
1j0006086biological_processpyruvate decarboxylation to acetyl-CoA
1j0006090biological_processpyruvate metabolic process
1j0006099biological_processtricarboxylic acid cycle
1j0009060biological_processaerobic respiration
1j0016407molecular_functionacetyltransferase activity
1j0016740molecular_functiontransferase activity
1j0016746molecular_functionacyltransferase activity
1j0042802molecular_functionidentical protein binding
1j0042867biological_processpyruvate catabolic process
1j0045254cellular_componentpyruvate dehydrogenase complex
1k0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1k0005739cellular_componentmitochondrion
1k0005759cellular_componentmitochondrial matrix
1k0006006biological_processglucose metabolic process
1k0006086biological_processpyruvate decarboxylation to acetyl-CoA
1k0006090biological_processpyruvate metabolic process
1k0006099biological_processtricarboxylic acid cycle
1k0009060biological_processaerobic respiration
1k0016407molecular_functionacetyltransferase activity
1k0016740molecular_functiontransferase activity
1k0016746molecular_functionacyltransferase activity
1k0042802molecular_functionidentical protein binding
1k0042867biological_processpyruvate catabolic process
1k0045254cellular_componentpyruvate dehydrogenase complex
1l0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1l0005739cellular_componentmitochondrion
1l0005759cellular_componentmitochondrial matrix
1l0006006biological_processglucose metabolic process
1l0006086biological_processpyruvate decarboxylation to acetyl-CoA
1l0006090biological_processpyruvate metabolic process
1l0006099biological_processtricarboxylic acid cycle
1l0009060biological_processaerobic respiration
1l0016407molecular_functionacetyltransferase activity
1l0016740molecular_functiontransferase activity
1l0016746molecular_functionacyltransferase activity
1l0042802molecular_functionidentical protein binding
1l0042867biological_processpyruvate catabolic process
1l0045254cellular_componentpyruvate dehydrogenase complex
1m0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1m0005739cellular_componentmitochondrion
1m0005759cellular_componentmitochondrial matrix
1m0006006biological_processglucose metabolic process
1m0006086biological_processpyruvate decarboxylation to acetyl-CoA
1m0006090biological_processpyruvate metabolic process
1m0006099biological_processtricarboxylic acid cycle
1m0009060biological_processaerobic respiration
1m0016407molecular_functionacetyltransferase activity
1m0016740molecular_functiontransferase activity
1m0016746molecular_functionacyltransferase activity
1m0042802molecular_functionidentical protein binding
1m0042867biological_processpyruvate catabolic process
1m0045254cellular_componentpyruvate dehydrogenase complex
1n0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1n0005739cellular_componentmitochondrion
1n0005759cellular_componentmitochondrial matrix
1n0006006biological_processglucose metabolic process
1n0006086biological_processpyruvate decarboxylation to acetyl-CoA
1n0006090biological_processpyruvate metabolic process
1n0006099biological_processtricarboxylic acid cycle
1n0009060biological_processaerobic respiration
1n0016407molecular_functionacetyltransferase activity
1n0016740molecular_functiontransferase activity
1n0016746molecular_functionacyltransferase activity
1n0042802molecular_functionidentical protein binding
1n0042867biological_processpyruvate catabolic process
1n0045254cellular_componentpyruvate dehydrogenase complex
1o0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1o0005739cellular_componentmitochondrion
1o0005759cellular_componentmitochondrial matrix
1o0006006biological_processglucose metabolic process
1o0006086biological_processpyruvate decarboxylation to acetyl-CoA
1o0006090biological_processpyruvate metabolic process
1o0006099biological_processtricarboxylic acid cycle
1o0009060biological_processaerobic respiration
1o0016407molecular_functionacetyltransferase activity
1o0016740molecular_functiontransferase activity
1o0016746molecular_functionacyltransferase activity
1o0042802molecular_functionidentical protein binding
1o0042867biological_processpyruvate catabolic process
1o0045254cellular_componentpyruvate dehydrogenase complex
1p0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1p0005739cellular_componentmitochondrion
1p0005759cellular_componentmitochondrial matrix
1p0006006biological_processglucose metabolic process
1p0006086biological_processpyruvate decarboxylation to acetyl-CoA
1p0006090biological_processpyruvate metabolic process
1p0006099biological_processtricarboxylic acid cycle
1p0009060biological_processaerobic respiration
1p0016407molecular_functionacetyltransferase activity
1p0016740molecular_functiontransferase activity
1p0016746molecular_functionacyltransferase activity
1p0042802molecular_functionidentical protein binding
1p0042867biological_processpyruvate catabolic process
1p0045254cellular_componentpyruvate dehydrogenase complex
1q0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1q0005739cellular_componentmitochondrion
1q0005759cellular_componentmitochondrial matrix
1q0006006biological_processglucose metabolic process
1q0006086biological_processpyruvate decarboxylation to acetyl-CoA
1q0006090biological_processpyruvate metabolic process
1q0006099biological_processtricarboxylic acid cycle
1q0009060biological_processaerobic respiration
1q0016407molecular_functionacetyltransferase activity
1q0016740molecular_functiontransferase activity
1q0016746molecular_functionacyltransferase activity
1q0042802molecular_functionidentical protein binding
1q0042867biological_processpyruvate catabolic process
1q0045254cellular_componentpyruvate dehydrogenase complex
1r0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1r0005739cellular_componentmitochondrion
1r0005759cellular_componentmitochondrial matrix
1r0006006biological_processglucose metabolic process
1r0006086biological_processpyruvate decarboxylation to acetyl-CoA
1r0006090biological_processpyruvate metabolic process
1r0006099biological_processtricarboxylic acid cycle
1r0009060biological_processaerobic respiration
1r0016407molecular_functionacetyltransferase activity
1r0016740molecular_functiontransferase activity
1r0016746molecular_functionacyltransferase activity
1r0042802molecular_functionidentical protein binding
1r0042867biological_processpyruvate catabolic process
1r0045254cellular_componentpyruvate dehydrogenase complex
1s0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1s0005739cellular_componentmitochondrion
1s0005759cellular_componentmitochondrial matrix
1s0006006biological_processglucose metabolic process
1s0006086biological_processpyruvate decarboxylation to acetyl-CoA
1s0006090biological_processpyruvate metabolic process
1s0006099biological_processtricarboxylic acid cycle
1s0009060biological_processaerobic respiration
1s0016407molecular_functionacetyltransferase activity
1s0016740molecular_functiontransferase activity
1s0016746molecular_functionacyltransferase activity
1s0042802molecular_functionidentical protein binding
1s0042867biological_processpyruvate catabolic process
1s0045254cellular_componentpyruvate dehydrogenase complex
1t0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1t0005739cellular_componentmitochondrion
1t0005759cellular_componentmitochondrial matrix
1t0006006biological_processglucose metabolic process
1t0006086biological_processpyruvate decarboxylation to acetyl-CoA
1t0006090biological_processpyruvate metabolic process
1t0006099biological_processtricarboxylic acid cycle
1t0009060biological_processaerobic respiration
1t0016407molecular_functionacetyltransferase activity
1t0016740molecular_functiontransferase activity
1t0016746molecular_functionacyltransferase activity
1t0042802molecular_functionidentical protein binding
1t0042867biological_processpyruvate catabolic process
1t0045254cellular_componentpyruvate dehydrogenase complex
1u0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1u0005739cellular_componentmitochondrion
1u0005759cellular_componentmitochondrial matrix
1u0006006biological_processglucose metabolic process
1u0006086biological_processpyruvate decarboxylation to acetyl-CoA
1u0006090biological_processpyruvate metabolic process
1u0006099biological_processtricarboxylic acid cycle
1u0009060biological_processaerobic respiration
1u0016407molecular_functionacetyltransferase activity
1u0016740molecular_functiontransferase activity
1u0016746molecular_functionacyltransferase activity
1u0042802molecular_functionidentical protein binding
1u0042867biological_processpyruvate catabolic process
1u0045254cellular_componentpyruvate dehydrogenase complex
1v0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1v0005739cellular_componentmitochondrion
1v0005759cellular_componentmitochondrial matrix
1v0006006biological_processglucose metabolic process
1v0006086biological_processpyruvate decarboxylation to acetyl-CoA
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1v0006099biological_processtricarboxylic acid cycle
1v0009060biological_processaerobic respiration
1v0016407molecular_functionacetyltransferase activity
1v0016740molecular_functiontransferase activity
1v0016746molecular_functionacyltransferase activity
1v0042802molecular_functionidentical protein binding
1v0042867biological_processpyruvate catabolic process
1v0045254cellular_componentpyruvate dehydrogenase complex
1w0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
1w0005739cellular_componentmitochondrion
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1w0006006biological_processglucose metabolic process
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1w0016407molecular_functionacetyltransferase activity
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1w0042867biological_processpyruvate catabolic process
1w0045254cellular_componentpyruvate dehydrogenase complex
1x0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
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1x0005759cellular_componentmitochondrial matrix
1x0006006biological_processglucose metabolic process
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1x0006099biological_processtricarboxylic acid cycle
1x0009060biological_processaerobic respiration
1x0016407molecular_functionacetyltransferase activity
1x0016740molecular_functiontransferase activity
1x0016746molecular_functionacyltransferase activity
1x0042802molecular_functionidentical protein binding
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1z0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
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1z0009060biological_processaerobic respiration
1z0016407molecular_functionacetyltransferase activity
1z0016740molecular_functiontransferase activity
1z0016746molecular_functionacyltransferase activity
1z0042802molecular_functionidentical protein binding
1z0042867biological_processpyruvate catabolic process
1z0045254cellular_componentpyruvate dehydrogenase complex
2a0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
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2a0005759cellular_componentmitochondrial matrix
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2a0006086biological_processpyruvate decarboxylation to acetyl-CoA
2a0006090biological_processpyruvate metabolic process
2a0006099biological_processtricarboxylic acid cycle
2a0009060biological_processaerobic respiration
2a0016407molecular_functionacetyltransferase activity
2a0016740molecular_functiontransferase activity
2a0016746molecular_functionacyltransferase activity
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2a0045254cellular_componentpyruvate dehydrogenase complex
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2b0006099biological_processtricarboxylic acid cycle
2b0009060biological_processaerobic respiration
2b0016407molecular_functionacetyltransferase activity
2b0016740molecular_functiontransferase activity
2b0016746molecular_functionacyltransferase activity
2b0042802molecular_functionidentical protein binding
2b0042867biological_processpyruvate catabolic process
2b0045254cellular_componentpyruvate dehydrogenase complex
2c0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2c0005739cellular_componentmitochondrion
2c0005759cellular_componentmitochondrial matrix
2c0006006biological_processglucose metabolic process
2c0006086biological_processpyruvate decarboxylation to acetyl-CoA
2c0006090biological_processpyruvate metabolic process
2c0006099biological_processtricarboxylic acid cycle
2c0009060biological_processaerobic respiration
2c0016407molecular_functionacetyltransferase activity
2c0016740molecular_functiontransferase activity
2c0016746molecular_functionacyltransferase activity
2c0042802molecular_functionidentical protein binding
2c0042867biological_processpyruvate catabolic process
2c0045254cellular_componentpyruvate dehydrogenase complex
2d0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2d0005739cellular_componentmitochondrion
2d0005759cellular_componentmitochondrial matrix
2d0006006biological_processglucose metabolic process
2d0006086biological_processpyruvate decarboxylation to acetyl-CoA
2d0006090biological_processpyruvate metabolic process
2d0006099biological_processtricarboxylic acid cycle
2d0009060biological_processaerobic respiration
2d0016407molecular_functionacetyltransferase activity
2d0016740molecular_functiontransferase activity
2d0016746molecular_functionacyltransferase activity
2d0042802molecular_functionidentical protein binding
2d0042867biological_processpyruvate catabolic process
2d0045254cellular_componentpyruvate dehydrogenase complex
2e0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2e0005739cellular_componentmitochondrion
2e0005759cellular_componentmitochondrial matrix
2e0006006biological_processglucose metabolic process
2e0006086biological_processpyruvate decarboxylation to acetyl-CoA
2e0006090biological_processpyruvate metabolic process
2e0006099biological_processtricarboxylic acid cycle
2e0009060biological_processaerobic respiration
2e0016407molecular_functionacetyltransferase activity
2e0016740molecular_functiontransferase activity
2e0016746molecular_functionacyltransferase activity
2e0042802molecular_functionidentical protein binding
2e0042867biological_processpyruvate catabolic process
2e0045254cellular_componentpyruvate dehydrogenase complex
2f0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2f0005739cellular_componentmitochondrion
2f0005759cellular_componentmitochondrial matrix
2f0006006biological_processglucose metabolic process
2f0006086biological_processpyruvate decarboxylation to acetyl-CoA
2f0006090biological_processpyruvate metabolic process
2f0006099biological_processtricarboxylic acid cycle
2f0009060biological_processaerobic respiration
2f0016407molecular_functionacetyltransferase activity
2f0016740molecular_functiontransferase activity
2f0016746molecular_functionacyltransferase activity
2f0042802molecular_functionidentical protein binding
2f0042867biological_processpyruvate catabolic process
2f0045254cellular_componentpyruvate dehydrogenase complex
2g0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2g0005739cellular_componentmitochondrion
2g0005759cellular_componentmitochondrial matrix
2g0006006biological_processglucose metabolic process
2g0006086biological_processpyruvate decarboxylation to acetyl-CoA
2g0006090biological_processpyruvate metabolic process
2g0006099biological_processtricarboxylic acid cycle
2g0009060biological_processaerobic respiration
2g0016407molecular_functionacetyltransferase activity
2g0016740molecular_functiontransferase activity
2g0016746molecular_functionacyltransferase activity
2g0042802molecular_functionidentical protein binding
2g0042867biological_processpyruvate catabolic process
2g0045254cellular_componentpyruvate dehydrogenase complex
2h0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2h0005739cellular_componentmitochondrion
2h0005759cellular_componentmitochondrial matrix
2h0006006biological_processglucose metabolic process
2h0006086biological_processpyruvate decarboxylation to acetyl-CoA
2h0006090biological_processpyruvate metabolic process
2h0006099biological_processtricarboxylic acid cycle
2h0009060biological_processaerobic respiration
2h0016407molecular_functionacetyltransferase activity
2h0016740molecular_functiontransferase activity
2h0016746molecular_functionacyltransferase activity
2h0042802molecular_functionidentical protein binding
2h0042867biological_processpyruvate catabolic process
2h0045254cellular_componentpyruvate dehydrogenase complex
2i0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2i0005739cellular_componentmitochondrion
2i0005759cellular_componentmitochondrial matrix
2i0006006biological_processglucose metabolic process
2i0006086biological_processpyruvate decarboxylation to acetyl-CoA
2i0006090biological_processpyruvate metabolic process
2i0006099biological_processtricarboxylic acid cycle
2i0009060biological_processaerobic respiration
2i0016407molecular_functionacetyltransferase activity
2i0016740molecular_functiontransferase activity
2i0016746molecular_functionacyltransferase activity
2i0042802molecular_functionidentical protein binding
2i0042867biological_processpyruvate catabolic process
2i0045254cellular_componentpyruvate dehydrogenase complex
2j0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2j0005739cellular_componentmitochondrion
2j0005759cellular_componentmitochondrial matrix
2j0006006biological_processglucose metabolic process
2j0006086biological_processpyruvate decarboxylation to acetyl-CoA
2j0006090biological_processpyruvate metabolic process
2j0006099biological_processtricarboxylic acid cycle
2j0009060biological_processaerobic respiration
2j0016407molecular_functionacetyltransferase activity
2j0016740molecular_functiontransferase activity
2j0016746molecular_functionacyltransferase activity
2j0042802molecular_functionidentical protein binding
2j0042867biological_processpyruvate catabolic process
2j0045254cellular_componentpyruvate dehydrogenase complex
2k0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2k0005739cellular_componentmitochondrion
2k0005759cellular_componentmitochondrial matrix
2k0006006biological_processglucose metabolic process
2k0006086biological_processpyruvate decarboxylation to acetyl-CoA
2k0006090biological_processpyruvate metabolic process
2k0006099biological_processtricarboxylic acid cycle
2k0009060biological_processaerobic respiration
2k0016407molecular_functionacetyltransferase activity
2k0016740molecular_functiontransferase activity
2k0016746molecular_functionacyltransferase activity
2k0042802molecular_functionidentical protein binding
2k0042867biological_processpyruvate catabolic process
2k0045254cellular_componentpyruvate dehydrogenase complex
2l0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2l0005739cellular_componentmitochondrion
2l0005759cellular_componentmitochondrial matrix
2l0006006biological_processglucose metabolic process
2l0006086biological_processpyruvate decarboxylation to acetyl-CoA
2l0006090biological_processpyruvate metabolic process
2l0006099biological_processtricarboxylic acid cycle
2l0009060biological_processaerobic respiration
2l0016407molecular_functionacetyltransferase activity
2l0016740molecular_functiontransferase activity
2l0016746molecular_functionacyltransferase activity
2l0042802molecular_functionidentical protein binding
2l0042867biological_processpyruvate catabolic process
2l0045254cellular_componentpyruvate dehydrogenase complex
2m0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2m0005739cellular_componentmitochondrion
2m0005759cellular_componentmitochondrial matrix
2m0006006biological_processglucose metabolic process
2m0006086biological_processpyruvate decarboxylation to acetyl-CoA
2m0006090biological_processpyruvate metabolic process
2m0006099biological_processtricarboxylic acid cycle
2m0009060biological_processaerobic respiration
2m0016407molecular_functionacetyltransferase activity
2m0016740molecular_functiontransferase activity
2m0016746molecular_functionacyltransferase activity
2m0042802molecular_functionidentical protein binding
2m0042867biological_processpyruvate catabolic process
2m0045254cellular_componentpyruvate dehydrogenase complex
2n0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2n0005739cellular_componentmitochondrion
2n0005759cellular_componentmitochondrial matrix
2n0006006biological_processglucose metabolic process
2n0006086biological_processpyruvate decarboxylation to acetyl-CoA
2n0006090biological_processpyruvate metabolic process
2n0006099biological_processtricarboxylic acid cycle
2n0009060biological_processaerobic respiration
2n0016407molecular_functionacetyltransferase activity
2n0016740molecular_functiontransferase activity
2n0016746molecular_functionacyltransferase activity
2n0042802molecular_functionidentical protein binding
2n0042867biological_processpyruvate catabolic process
2n0045254cellular_componentpyruvate dehydrogenase complex
2o0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2o0005739cellular_componentmitochondrion
2o0005759cellular_componentmitochondrial matrix
2o0006006biological_processglucose metabolic process
2o0006086biological_processpyruvate decarboxylation to acetyl-CoA
2o0006090biological_processpyruvate metabolic process
2o0006099biological_processtricarboxylic acid cycle
2o0009060biological_processaerobic respiration
2o0016407molecular_functionacetyltransferase activity
2o0016740molecular_functiontransferase activity
2o0016746molecular_functionacyltransferase activity
2o0042802molecular_functionidentical protein binding
2o0042867biological_processpyruvate catabolic process
2o0045254cellular_componentpyruvate dehydrogenase complex
2p0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2p0005739cellular_componentmitochondrion
2p0005759cellular_componentmitochondrial matrix
2p0006006biological_processglucose metabolic process
2p0006086biological_processpyruvate decarboxylation to acetyl-CoA
2p0006090biological_processpyruvate metabolic process
2p0006099biological_processtricarboxylic acid cycle
2p0009060biological_processaerobic respiration
2p0016407molecular_functionacetyltransferase activity
2p0016740molecular_functiontransferase activity
2p0016746molecular_functionacyltransferase activity
2p0042802molecular_functionidentical protein binding
2p0042867biological_processpyruvate catabolic process
2p0045254cellular_componentpyruvate dehydrogenase complex
2q0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2q0005739cellular_componentmitochondrion
2q0005759cellular_componentmitochondrial matrix
2q0006006biological_processglucose metabolic process
2q0006086biological_processpyruvate decarboxylation to acetyl-CoA
2q0006090biological_processpyruvate metabolic process
2q0006099biological_processtricarboxylic acid cycle
2q0009060biological_processaerobic respiration
2q0016407molecular_functionacetyltransferase activity
2q0016740molecular_functiontransferase activity
2q0016746molecular_functionacyltransferase activity
2q0042802molecular_functionidentical protein binding
2q0042867biological_processpyruvate catabolic process
2q0045254cellular_componentpyruvate dehydrogenase complex
2r0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2r0005739cellular_componentmitochondrion
2r0005759cellular_componentmitochondrial matrix
2r0006006biological_processglucose metabolic process
2r0006086biological_processpyruvate decarboxylation to acetyl-CoA
2r0006090biological_processpyruvate metabolic process
2r0006099biological_processtricarboxylic acid cycle
2r0009060biological_processaerobic respiration
2r0016407molecular_functionacetyltransferase activity
2r0016740molecular_functiontransferase activity
2r0016746molecular_functionacyltransferase activity
2r0042802molecular_functionidentical protein binding
2r0042867biological_processpyruvate catabolic process
2r0045254cellular_componentpyruvate dehydrogenase complex
2s0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2s0005739cellular_componentmitochondrion
2s0005759cellular_componentmitochondrial matrix
2s0006006biological_processglucose metabolic process
2s0006086biological_processpyruvate decarboxylation to acetyl-CoA
2s0006090biological_processpyruvate metabolic process
2s0006099biological_processtricarboxylic acid cycle
2s0009060biological_processaerobic respiration
2s0016407molecular_functionacetyltransferase activity
2s0016740molecular_functiontransferase activity
2s0016746molecular_functionacyltransferase activity
2s0042802molecular_functionidentical protein binding
2s0042867biological_processpyruvate catabolic process
2s0045254cellular_componentpyruvate dehydrogenase complex
2t0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2t0005739cellular_componentmitochondrion
2t0005759cellular_componentmitochondrial matrix
2t0006006biological_processglucose metabolic process
2t0006086biological_processpyruvate decarboxylation to acetyl-CoA
2t0006090biological_processpyruvate metabolic process
2t0006099biological_processtricarboxylic acid cycle
2t0009060biological_processaerobic respiration
2t0016407molecular_functionacetyltransferase activity
2t0016740molecular_functiontransferase activity
2t0016746molecular_functionacyltransferase activity
2t0042802molecular_functionidentical protein binding
2t0042867biological_processpyruvate catabolic process
2t0045254cellular_componentpyruvate dehydrogenase complex
2u0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2u0005739cellular_componentmitochondrion
2u0005759cellular_componentmitochondrial matrix
2u0006006biological_processglucose metabolic process
2u0006086biological_processpyruvate decarboxylation to acetyl-CoA
2u0006090biological_processpyruvate metabolic process
2u0006099biological_processtricarboxylic acid cycle
2u0009060biological_processaerobic respiration
2u0016407molecular_functionacetyltransferase activity
2u0016740molecular_functiontransferase activity
2u0016746molecular_functionacyltransferase activity
2u0042802molecular_functionidentical protein binding
2u0042867biological_processpyruvate catabolic process
2u0045254cellular_componentpyruvate dehydrogenase complex
2v0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2v0005739cellular_componentmitochondrion
2v0005759cellular_componentmitochondrial matrix
2v0006006biological_processglucose metabolic process
2v0006086biological_processpyruvate decarboxylation to acetyl-CoA
2v0006090biological_processpyruvate metabolic process
2v0006099biological_processtricarboxylic acid cycle
2v0009060biological_processaerobic respiration
2v0016407molecular_functionacetyltransferase activity
2v0016740molecular_functiontransferase activity
2v0016746molecular_functionacyltransferase activity
2v0042802molecular_functionidentical protein binding
2v0042867biological_processpyruvate catabolic process
2v0045254cellular_componentpyruvate dehydrogenase complex
2w0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2w0005739cellular_componentmitochondrion
2w0005759cellular_componentmitochondrial matrix
2w0006006biological_processglucose metabolic process
2w0006086biological_processpyruvate decarboxylation to acetyl-CoA
2w0006090biological_processpyruvate metabolic process
2w0006099biological_processtricarboxylic acid cycle
2w0009060biological_processaerobic respiration
2w0016407molecular_functionacetyltransferase activity
2w0016740molecular_functiontransferase activity
2w0016746molecular_functionacyltransferase activity
2w0042802molecular_functionidentical protein binding
2w0042867biological_processpyruvate catabolic process
2w0045254cellular_componentpyruvate dehydrogenase complex
2x0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2x0005739cellular_componentmitochondrion
2x0005759cellular_componentmitochondrial matrix
2x0006006biological_processglucose metabolic process
2x0006086biological_processpyruvate decarboxylation to acetyl-CoA
2x0006090biological_processpyruvate metabolic process
2x0006099biological_processtricarboxylic acid cycle
2x0009060biological_processaerobic respiration
2x0016407molecular_functionacetyltransferase activity
2x0016740molecular_functiontransferase activity
2x0016746molecular_functionacyltransferase activity
2x0042802molecular_functionidentical protein binding
2x0042867biological_processpyruvate catabolic process
2x0045254cellular_componentpyruvate dehydrogenase complex
2y0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2y0005739cellular_componentmitochondrion
2y0005759cellular_componentmitochondrial matrix
2y0006006biological_processglucose metabolic process
2y0006086biological_processpyruvate decarboxylation to acetyl-CoA
2y0006090biological_processpyruvate metabolic process
2y0006099biological_processtricarboxylic acid cycle
2y0009060biological_processaerobic respiration
2y0016407molecular_functionacetyltransferase activity
2y0016740molecular_functiontransferase activity
2y0016746molecular_functionacyltransferase activity
2y0042802molecular_functionidentical protein binding
2y0042867biological_processpyruvate catabolic process
2y0045254cellular_componentpyruvate dehydrogenase complex
2z0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
2z0005739cellular_componentmitochondrion
2z0005759cellular_componentmitochondrial matrix
2z0006006biological_processglucose metabolic process
2z0006086biological_processpyruvate decarboxylation to acetyl-CoA
2z0006090biological_processpyruvate metabolic process
2z0006099biological_processtricarboxylic acid cycle
2z0009060biological_processaerobic respiration
2z0016407molecular_functionacetyltransferase activity
2z0016740molecular_functiontransferase activity
2z0016746molecular_functionacyltransferase activity
2z0042802molecular_functionidentical protein binding
2z0042867biological_processpyruvate catabolic process
2z0045254cellular_componentpyruvate dehydrogenase complex
3a0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
3a0005739cellular_componentmitochondrion
3a0005759cellular_componentmitochondrial matrix
3a0006006biological_processglucose metabolic process
3a0006086biological_processpyruvate decarboxylation to acetyl-CoA
3a0006090biological_processpyruvate metabolic process
3a0006099biological_processtricarboxylic acid cycle
3a0009060biological_processaerobic respiration
3a0016407molecular_functionacetyltransferase activity
3a0016740molecular_functiontransferase activity
3a0016746molecular_functionacyltransferase activity
3a0042802molecular_functionidentical protein binding
3a0042867biological_processpyruvate catabolic process
3a0045254cellular_componentpyruvate dehydrogenase complex
3b0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
3b0005739cellular_componentmitochondrion
3b0005759cellular_componentmitochondrial matrix
3b0006006biological_processglucose metabolic process
3b0006086biological_processpyruvate decarboxylation to acetyl-CoA
3b0006090biological_processpyruvate metabolic process
3b0006099biological_processtricarboxylic acid cycle
3b0009060biological_processaerobic respiration
3b0016407molecular_functionacetyltransferase activity
3b0016740molecular_functiontransferase activity
3b0016746molecular_functionacyltransferase activity
3b0042802molecular_functionidentical protein binding
3b0042867biological_processpyruvate catabolic process
3b0045254cellular_componentpyruvate dehydrogenase complex
3c0004742molecular_functiondihydrolipoyllysine-residue acetyltransferase activity
3c0005739cellular_componentmitochondrion
3c0005759cellular_componentmitochondrial matrix
3c0006006biological_processglucose metabolic process
3c0006086biological_processpyruvate decarboxylation to acetyl-CoA
3c0006090biological_processpyruvate metabolic process
3c0006099biological_processtricarboxylic acid cycle
3c0009060biological_processaerobic respiration
3c0016407molecular_functionacetyltransferase activity
3c0016740molecular_functiontransferase activity
3c0016746molecular_functionacyltransferase activity
3c0042802molecular_functionidentical protein binding
3c0042867biological_processpyruvate catabolic process
3c0045254cellular_componentpyruvate dehydrogenase complex
Functional Information from PROSITE/UniProt
site_idPS00178
Number of Residues12
DetailsAA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PalSPtMTMGTV
ChainResidueDetails
01PRO224-VAL235
site_idPS00189
Number of Residues30
DetailsLIPOYL 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. GekInegELIaeVETdKATvgFesveeCyM
ChainResidueDetails
01GLY116-MET145
01GLY243-LEU272
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues120
DetailsActive site: {"evidences":[{"source":"UniProtKB","id":"Q9N0F1","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues300
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"P11181","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues60
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P10515","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues120
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q8BMF4","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

247947

PDB entries from 2026-01-21

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