7UN3
Complex of UBE2O with NAP1L1 and ubiquitylated uL2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002181 | biological_process | cytoplasmic translation |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003735 | molecular_function | structural constituent of ribosome |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005840 | cellular_component | ribosome |
| A | 0005925 | cellular_component | focal adhesion |
| A | 0006412 | biological_process | translation |
| A | 0006513 | biological_process | protein monoubiquitination |
| A | 0014069 | cellular_component | postsynaptic density |
| A | 0015934 | cellular_component | large ribosomal subunit |
| A | 0016020 | cellular_component | membrane |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016604 | cellular_component | nuclear body |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019843 | molecular_function | rRNA binding |
| A | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| A | 0022626 | cellular_component | cytosolic ribosome |
| A | 0030513 | biological_process | positive regulation of BMP signaling pathway |
| A | 0042147 | biological_process | retrograde transport, endosome to Golgi |
| A | 0045202 | cellular_component | synapse |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
| A | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
| A | 0070534 | biological_process | protein K63-linked ubiquitination |
| A | 0098794 | cellular_component | postsynapse |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
| B | 0000785 | cellular_component | chromatin |
| B | 0003682 | molecular_function | chromatin binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006260 | biological_process | DNA replication |
| B | 0006334 | biological_process | nucleosome assembly |
| B | 0007399 | biological_process | nervous system development |
| B | 0008284 | biological_process | positive regulation of cell population proliferation |
| B | 0016020 | cellular_component | membrane |
| B | 0042393 | molecular_function | histone binding |
| B | 0042470 | cellular_component | melanosome |
| B | 0050769 | biological_process | positive regulation of neurogenesis |
| B | 0140713 | molecular_function | histone chaperone activity |
| B | 2000179 | biological_process | positive regulation of neural precursor cell proliferation |
| C | 0000785 | cellular_component | chromatin |
| C | 0003682 | molecular_function | chromatin binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006260 | biological_process | DNA replication |
| C | 0006334 | biological_process | nucleosome assembly |
| C | 0007399 | biological_process | nervous system development |
| C | 0008284 | biological_process | positive regulation of cell population proliferation |
| C | 0016020 | cellular_component | membrane |
| C | 0042393 | molecular_function | histone binding |
| C | 0042470 | cellular_component | melanosome |
| C | 0050769 | biological_process | positive regulation of neurogenesis |
| C | 0140713 | molecular_function | histone chaperone activity |
| C | 2000179 | biological_process | positive regulation of neural precursor cell proliferation |
| D | 0002181 | biological_process | cytoplasmic translation |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003735 | molecular_function | structural constituent of ribosome |
| D | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0005840 | cellular_component | ribosome |
| D | 0005925 | cellular_component | focal adhesion |
| D | 0006412 | biological_process | translation |
| D | 0006513 | biological_process | protein monoubiquitination |
| D | 0014069 | cellular_component | postsynaptic density |
| D | 0015934 | cellular_component | large ribosomal subunit |
| D | 0016020 | cellular_component | membrane |
| D | 0016567 | biological_process | protein ubiquitination |
| D | 0016604 | cellular_component | nuclear body |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019843 | molecular_function | rRNA binding |
| D | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| D | 0022626 | cellular_component | cytosolic ribosome |
| D | 0030513 | biological_process | positive regulation of BMP signaling pathway |
| D | 0042147 | biological_process | retrograde transport, endosome to Golgi |
| D | 0045202 | cellular_component | synapse |
| D | 0061630 | molecular_function | ubiquitin protein ligase activity |
| D | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
| D | 0070534 | biological_process | protein K63-linked ubiquitination |
| D | 0098794 | cellular_component | postsynapse |
| D | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330 |
| Chain | Residue | Details |
| B | ALA2 | |
| C | ALA2 | |
| A | ARG-351 | |
| A | ARG-333 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| B | SER10 | |
| B | SER143 | |
| C | SER10 | |
| C | SER143 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | THR62 | |
| C | THR62 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P28656 |
| Chain | Residue | Details |
| B | THR64 | |
| C | THR64 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | SER69 | |
| C | SER69 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| B | LYS116 | |
| C | LYS116 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Cysteine methyl ester => ECO:0000305 |
| Chain | Residue | Details |
| B | CYS388 | |
| A | LYS-77 | |
| C | CYS388 | |
| D | LYS120 | |
| D | LYS227 | |
| D | LYS312 | |
| D | LYS328 | |
| A | LYS-285 | |
| A | LYS-178 | |
| A | LYS-93 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | LIPID: S-farnesyl cysteine => ECO:0000269|PubMed:15308774 |
| Chain | Residue | Details |
| B | CYS388 | |
| C | CYS388 | |
| A | LYS-394 | |
| A | LYS-357 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 |
| Chain | Residue | Details |
| D | LYS27 | |
| A | LYS-378 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127 |
| Chain | Residue | Details |
| D | LYS29 | |
| A | LYS-376 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 |
| Chain | Residue | Details |
| D | LYS33 | |
| A | LYS-372 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106 |
| Chain | Residue | Details |
| D | LYS63 | |
| A | LYS-342 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) |
| Chain | Residue | Details |
| D | VAL76 | |
| A | VAL-329 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | MOD_RES: (3S)-3-hydroxyhistidine => ECO:0000269|PubMed:23103944 |
| Chain | Residue | Details |
| D | HIS294 | |
| A | HIS-111 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 2 |
| Details | ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388 |
| Chain | Residue | Details |
| D | LYS1445 | |
| A | LYS1040 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| D | SER455 | |
| A | SER50 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| D | SER492 | |
| A | SER87 |
| site_id | SWS_FT_FI18 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| D | SER494 | |
| A | SER89 |
| site_id | SWS_FT_FI19 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| D | SER804 | |
| D | SER806 | |
| A | SER399 | |
| A | SER401 |
| site_id | SWS_FT_FI20 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| D | SER846 | |
| A | SER441 |
| site_id | SWS_FT_FI21 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| D | THR893 | |
| D | THR896 | |
| A | THR488 | |
| A | THR491 |
| site_id | SWS_FT_FI22 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| D | SER920 | |
| A | SER515 |
| site_id | SWS_FT_FI23 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| D | SER1241 | |
| A | SER836 |
| site_id | SWS_FT_FI24 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q6ZPJ3 |
| Chain | Residue | Details |
| D | THR1243 | |
| A | THR838 |
| site_id | SWS_FT_FI25 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q6ZPJ3 |
| Chain | Residue | Details |
| D | SER1244 | |
| A | SER839 |
| site_id | SWS_FT_FI26 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| D | SER1301 | |
| A | SER896 |
