7UJY
Estrogen receptor alpha ligand binding domain Y537S mutant in complex with a methylated lasofoxifene derivative that enhances estrogen receptor alpha nuclear resonance time
Replaces: 6VPKFunctional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE |
| Chain | Residue | Details |
| B | GLU353 | |
| D | GLU353 | |
| D | ARG394 | |
| D | HIS524 | |
| B | ARG394 | |
| B | HIS524 | |
| A | GLU353 | |
| A | ARG394 | |
| A | HIS524 | |
| C | GLU353 | |
| C | ARG394 | |
| C | HIS524 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| B | SER537 | |
| A | SER537 | |
| C | SER537 | |
| D | SER537 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| B | CYS447 | |
| A | CYS447 | |
| C | CYS447 | |
| D | CYS447 |
