Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7UGU

Structure of enolase from streptococcus pyogenes

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000015	cellular_component	phosphopyruvate hydratase complex
A	0000287	molecular_function	magnesium ion binding
A	0004634	molecular_function	phosphopyruvate hydratase activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0006096	biological_process	glycolytic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0009986	cellular_component	cell surface
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
B	0000015	cellular_component	phosphopyruvate hydratase complex
B	0000287	molecular_function	magnesium ion binding
B	0004634	molecular_function	phosphopyruvate hydratase activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0006096	biological_process	glycolytic process
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0009986	cellular_component	cell surface
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding
C	0000015	cellular_component	phosphopyruvate hydratase complex
C	0000287	molecular_function	magnesium ion binding
C	0004634	molecular_function	phosphopyruvate hydratase activity
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0006096	biological_process	glycolytic process
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0009986	cellular_component	cell surface
C	0016829	molecular_function	lyase activity
C	0046872	molecular_function	metal ion binding
D	0000015	cellular_component	phosphopyruvate hydratase complex
D	0000287	molecular_function	magnesium ion binding
D	0004634	molecular_function	phosphopyruvate hydratase activity
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0006096	biological_process	glycolytic process
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0009986	cellular_component	cell surface
D	0016829	molecular_function	lyase activity
D	0046872	molecular_function	metal ion binding
E	0000015	cellular_component	phosphopyruvate hydratase complex
E	0000287	molecular_function	magnesium ion binding
E	0004634	molecular_function	phosphopyruvate hydratase activity
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0006096	biological_process	glycolytic process
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0009986	cellular_component	cell surface
E	0016829	molecular_function	lyase activity
E	0046872	molecular_function	metal ion binding
F	0000015	cellular_component	phosphopyruvate hydratase complex
F	0000287	molecular_function	magnesium ion binding
F	0004634	molecular_function	phosphopyruvate hydratase activity
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0006096	biological_process	glycolytic process
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0009986	cellular_component	cell surface
F	0016829	molecular_function	lyase activity
F	0046872	molecular_function	metal ion binding
G	0000015	cellular_component	phosphopyruvate hydratase complex
G	0000287	molecular_function	magnesium ion binding
G	0004634	molecular_function	phosphopyruvate hydratase activity
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0006096	biological_process	glycolytic process
G	0009274	cellular_component	peptidoglycan-based cell wall
G	0009986	cellular_component	cell surface
G	0016829	molecular_function	lyase activity
G	0046872	molecular_function	metal ion binding
H	0000015	cellular_component	phosphopyruvate hydratase complex
H	0000287	molecular_function	magnesium ion binding
H	0004634	molecular_function	phosphopyruvate hydratase activity
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0006096	biological_process	glycolytic process
H	0009274	cellular_component	peptidoglycan-based cell wall
H	0009986	cellular_component	cell surface
H	0016829	molecular_function	lyase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00164
Number of Residues	14
Details	ENOLASE Enolase signature. ILIKvNQIGTLTET

Chain	Residue	Details
G	ILE341-THR354

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton donor => ECO:0000255\|HAMAP-Rule:MF_00318

Chain	Residue	Details
G	GLU205
H	GLU205
E	GLU205
F	GLU205
C	GLU205
D	GLU205
A	GLU205
B	GLU205

site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000255\|HAMAP-Rule:MF_00318

Chain	Residue	Details
G	LYS344
H	LYS344
E	LYS344
F	LYS344
C	LYS344
D	LYS344
A	LYS344
B	LYS344

site_id	SWS_FT_FI3
Number of Residues	56
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00318

Chain	Residue	Details
G	HIS155
H	ASP243
H	GLU292
H	ASP319
H	SER371
H	LYS395
E	HIS155
E	GLU164
E	ASP243
E	GLU292
E	ASP319
G	GLU164
E	SER371
E	LYS395
F	HIS155
F	GLU164
F	ASP243
F	GLU292
F	ASP319
F	SER371
F	LYS395
C	HIS155
G	ASP243
C	GLU164
C	ASP243
C	GLU292
C	ASP319
C	SER371
C	LYS395
D	HIS155
D	GLU164
D	ASP243
D	GLU292
G	GLU292
D	ASP319
D	SER371
D	LYS395
A	HIS155
A	GLU164
A	ASP243
A	GLU292
A	ASP319
A	SER371
A	LYS395
G	ASP319
B	HIS155
B	GLU164
B	ASP243
B	GLU292
B	ASP319
B	SER371
B	LYS395
G	SER371
G	LYS395
H	HIS155
H	GLU164

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: covalent; in inhibited form => ECO:0000255\|HAMAP-Rule:MF_00318

Chain	Residue	Details
G	LYS344
H	LYS344
E	LYS344
F	LYS344
C	LYS344
D	LYS344
A	LYS344
B	LYS344

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)