7UGK
Crystal structure of the human queuine salvage enzyme DUF2419, wild-type apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006400 | biological_process | tRNA modification |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0043096 | biological_process | purine nucleobase salvage |
| A | 0043174 | biological_process | nucleoside salvage |
| A | 0106432 | molecular_function | queuosine nucleosidase activity |
| A | 0160254 | biological_process | tRNA queuosine(34) biosynthetic process from salvaged queuosine or its precursors |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006400 | biological_process | tRNA modification |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0043096 | biological_process | purine nucleobase salvage |
| B | 0043174 | biological_process | nucleoside salvage |
| B | 0106432 | molecular_function | queuosine nucleosidase activity |
| B | 0160254 | biological_process | tRNA queuosine(34) biosynthetic process from salvaged queuosine or its precursors |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile or transition state stabilizer","evidences":[{"source":"UniProtKB","id":"D1C7A6","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"36610787","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8DL3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
