7UGK
Crystal structure of the human queuine salvage enzyme DUF2419, wild-type apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003674 | molecular_function | molecular_function |
| A | 0005515 | molecular_function | protein binding |
| A | 0005575 | cellular_component | cellular_component |
| A | 0008150 | biological_process | biological_process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0043174 | biological_process | nucleoside salvage |
| A | 0101030 | biological_process | tRNA-guanine transglycosylation |
| B | 0003674 | molecular_function | molecular_function |
| B | 0005515 | molecular_function | protein binding |
| B | 0005575 | cellular_component | cellular_component |
| B | 0008150 | biological_process | biological_process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0043174 | biological_process | nucleoside salvage |
| B | 0101030 | biological_process | tRNA-guanine transglycosylation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile or transition state stabilizer => ECO:0000250|UniProtKB:D1C7A6 |
| Chain | Residue | Details |
| A | ASP239 | |
| B | ASP239 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:36610787, ECO:0007744|PDB:8DL3 |
| Chain | Residue | Details |
| A | HIS53 | |
| A | PHE237 | |
| A | ASP239 | |
| A | ASP314 | |
| A | TYR315 | |
| A | ASP319 | |
| B | HIS53 | |
| B | PHE237 | |
| B | ASP239 | |
| B | ASP314 | |
| B | TYR315 | |
| B | ASP319 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 |
