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7U7N

IL-27 quaternary receptor signaling complex

Functional Information from GO Data
ChainGOidnamespacecontents
C0004896molecular_functioncytokine receptor activity
C0005125molecular_functioncytokine activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005788cellular_componentendoplasmic reticulum lumen
C0005886cellular_componentplasma membrane
C0006959biological_processhumoral immune response
C0009897cellular_componentexternal side of plasma membrane
C0016020cellular_componentmembrane
C0019221biological_processcytokine-mediated signaling pathway
C0019955molecular_functioncytokine binding
C0032729biological_processpositive regulation of type II interferon production
C0042088biological_processT-helper 1 type immune response
C0042098biological_processT cell proliferation
C0043235cellular_componentreceptor complex
C0045523molecular_functioninterleukin-27 receptor binding
C0046641biological_processpositive regulation of alpha-beta T cell proliferation
D0002230biological_processpositive regulation of defense response to virus by host
D0005102molecular_functionsignaling receptor binding
D0005125molecular_functioncytokine activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005788cellular_componentendoplasmic reticulum lumen
D0005829cellular_componentcytosol
D0006954biological_processinflammatory response
D0007165biological_processsignal transduction
D0009617biological_processresponse to bacterium
D0009986cellular_componentcell surface
D0032729biological_processpositive regulation of type II interferon production
D0042129biological_processregulation of T cell proliferation
D0045087biological_processinnate immune response
D0045523molecular_functioninterleukin-27 receptor binding
D0045625biological_processregulation of T-helper 1 cell differentiation
D0050688biological_processregulation of defense response to virus
D0140459biological_processresponse to Gram-positive bacterium
Functional Information from PROSITE/UniProt
site_idPS01354
Number of Residues41
DetailsHEMATOPO_REC_L_F3 Long hematopoietin receptor, soluble alpha chains family signature. IkPDPPegVrlsplaerq..LqvqWepPgSWpfpei.FsLkYwI
ChainResidueDetails
CILE127-ILE167

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
CASN55
CASN105

site_idSWS_FT_FI2
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11098061
ChainResidueDetails
BASN131
BASN157

site_idSWS_FT_FI3
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11098061, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:20489211
ChainResidueDetails
BASN227

226707

PDB entries from 2024-10-30

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